Review
Published on 29 Apr 2022
Considerations for Improving Metabolism Predictions for In Vitro to In Vivo Extrapolation
in In Vitro Toxicology
Frontiers in Toxicology
doi 10.3389/ftox.2022.894569
- 2,922 views
- 12 citations
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71 articles
Articles
Original Research
Published on 28 Apr 2022
A Case Study on Integrating a New Key Event Into an Existing Adverse Outcome Pathway on Oxidative DNA Damage: Challenges and Approaches in a Data-Rich Area
in In Vitro Toxicology
Frontiers in Toxicology
doi 10.3389/ftox.2022.827328
- 2,504 views
- 2 citations
Original Research
Published on 19 Apr 2022
Application of the Adverse Outcome Pathway Concept to In Vitro Nephrotoxicity Assessment: Kidney Injury due to Receptor-Mediated Endocytosis and Lysosomal Overload as a Case Study
in In Vitro Toxicology
Frontiers in Toxicology
doi 10.3389/ftox.2022.864441
- 8,046 views
- 5 citations
Perspective
Published on 30 Mar 2022
From Qualitative to Quantitative AOP: A Case Study of Neurodegeneration
in In Vitro Toxicology
Frontiers in Toxicology
doi 10.3389/ftox.2022.838729
- 2,640 views
- 2 citations
Original Research
Published on 24 Mar 2022
Integration of Adverse Outcome Pathways, Causal Networks and ‘Omics to Support Chemical Hazard Assessment
in In Vitro Toxicology
Frontiers in Toxicology
doi 10.3389/ftox.2022.786057
- 2,755 views
- 8 citations
Original Research
Published on 07 Mar 2022
Beyond AOPs: A Mechanistic Evaluation of NAMs in DART Testing
in In Vitro Toxicology
Frontiers in Toxicology
doi 10.3389/ftox.2022.838466
- 10,207 views
- 21 citations
Original Research
Published on 07 Mar 2022
Mapping Mechanistic Pathways of Acute Oral Systemic Toxicity Using Chemical Structure and Bioactivity Measurements
in In Vitro Toxicology
Frontiers in Toxicology
doi 10.3389/ftox.2022.824094
- 3,173 views
- 4 citations
Original Research
Published on 07 Mar 2022
From Causal Networks to Adverse Outcome Pathways: A Developmental Neurotoxicity Case Study
in In Vitro Toxicology
Frontiers in Toxicology
doi 10.3389/ftox.2022.815754
- 4,594 views
- 6 citations
Brief Research Report
Published on 28 Feb 2022
Dissecting Drug-Induced Cytotoxicity and Metabolic Dysfunction in Conditionally Immortalized Human Proximal Tubule Cells
in In Vitro Toxicology
Frontiers in Toxicology
doi 10.3389/ftox.2022.842396
- 6,442 views
- 11 citations
Original Research
Published on 16 Feb 2022
Use of Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes to Predict the Cardiotoxicity Potential of Next Generation Nicotine Products
in In Vitro Toxicology
Frontiers in Toxicology
doi 10.3389/ftox.2022.747508
- 4,416 views
- 7 citations
Methods
Published on 03 Feb 2022
Versatile Functional Energy Metabolism Platform Working From Research to Patient: An Integrated View of Cell Bioenergetics
in In Vitro Toxicology
Frontiers in Toxicology
doi 10.3389/ftox.2021.750431
- 2,520 views
Original Research
Published on 02 Feb 2022
Evaluation of Inhalation Exposures and Potential Health Impacts of Ingredient Mixtures Using in vitro to in vivo Extrapolation
in In Vitro Toxicology
Frontiers in Toxicology
doi 10.3389/ftox.2021.787756
- 3,728 views
- 6 citations
Original Research
Published on 19 Jan 2022
Exploration of the DARTable Genome- a Resource Enabling Data-Driven NAMs for Developmental and Reproductive Toxicity Prediction
in In Vitro Toxicology
Frontiers in Toxicology
doi 10.3389/ftox.2021.806311
- 3,732 views
- 5 citations
Original Research
Published on 14 Dec 2021
An Adverse Outcome Pathway for Decreased Lung Function Focusing on Mechanisms of Impaired Mucociliary Clearance Following Inhalation Exposure
in In Vitro Toxicology
Frontiers in Toxicology
doi 10.3389/ftox.2021.750254
- 4,494 views
- 14 citations
Perspective
Published on 04 Nov 2021
Canadian Regulatory Perspective on Next Generation Risk Assessments for Pest Control Products and Industrial Chemicals
in In Vitro Toxicology
Frontiers in Toxicology
doi 10.3389/ftox.2021.748406
- 6,849 views
- 22 citations
Mini Review
Published on 19 Jul 2021
Insect in vitro System for Toxicology Studies — Current and Future Perspectives
in In Vitro Toxicology
Frontiers in Toxicology
doi 10.3389/ftox.2021.671600
- 3,364 views
- 2 citations