Technology and Code

Published on 22 Jul 2024

Transforming environmental health datasets from the comparative toxicogenomics database into chord diagrams to visualize molecular mechanisms

in Computational Toxicology and Informatics

Brent Wyatt
Allan Peter Davis
Thomas C. Wiegers
Jolene Wiegers
Sakib Abrar
Daniela Sciaky
Fern Barkalow
Melissa Strong
Carolyn J. Mattingly

Frontiers in Toxicology

doi 10.3389/ftox.2024.1437884

1,082 views
1 citation

Perspective

Published on 19 Jul 2024

Safety of titanium dioxide (E171) as a food additive for humans

in Nanotoxicology

David B. Warheit

Frontiers in Toxicology

doi 10.3389/ftox.2024.1333746

4,247 views

Correction

Published on 19 Jul 2024

Corrigendum: Applying new approach methodologies to assess next-generation tobacco and nicotine products

in In Vitro Toxicology

David Thorne
Damian McHugh
Liam Simms
K. Monica Lee
Hitoshi Fujimoto
Sara Moses
Marianna Gaca

Frontiers in Toxicology

doi 10.3389/ftox.2024.1460271

462 views

Review

Published on 18 Jul 2024

Per- and poly-fluoroalkyl substances (PFAS) effects on lung health: a perspective on the current literature and future recommendations

in Environmental Toxicology

Megan E. Solan
Jin-Ah Park

Frontiers in Toxicology

doi 10.3389/ftox.2024.1423449

3,062 views

Review

Published on 17 Jul 2024

Unleashing the potential of cell painting assays for compound activities and hazards prediction

in In Vitro Toxicology

Floriane Odje
David Meijer
Elena von Coburg
Justin J. J. van der Hooft
Sebastian Dunst
Marnix H. Medema
Andrea Volkamer

Frontiers in Toxicology

doi 10.3389/ftox.2024.1401036

2,033 views
1 citation

Original Research

Published on 15 Jul 2024

Many human pharmaceuticals are weak inhibitors of the cytochrome P450 system in rainbow trout (Oncorhynchus mykiss) liver S9 fractions

in Environmental Toxicology

Tea Pihlaja
Timo Oksanen
Netta Vinkvist
Tiina Sikanen

Frontiers in Toxicology

doi 10.3389/ftox.2024.1406942

938 views
1 citation

Methods

Published on 15 Jul 2024

sendigR: an R package to leverage the value of CDISC SEND datasets for cross-study analysis

in Computational Toxicology and Informatics

K. Snyder
C. M. Sabbir Ahmed
Md Yousuf Ali
S. Butler
Michael DeNieu
W. Houser
B. Paisley
M. Rosentreter
W. Wang
B. Larsen

Frontiers in Toxicology

doi 10.3389/ftox.2024.1392686

977 views
1 citation

Original Research

Published on 10 Jul 2024

Bioactivation of cinnamic alcohol in a reconstructed human epidermis model and evaluation of sensitizing potency of the identified metabolites

in Immunotoxicology

Lorena Ndreu
Josefine Carlsson
David J. Ponting
Ida B. Niklasson
E. Johanna L. Stéen
Lukas McHugh
Niamh M. O’Boyle
Kristina Luthman
Ann-Therese Karlberg
Isabella Karlsson

Frontiers in Toxicology

doi 10.3389/ftox.2024.1398852

2,411 views

Editorial

Published on 02 Jul 2024

Editorial: Next generation chemical risk assessment: integration of advances in toxicology, biology and computation

in Computational Toxicology and Informatics

Kan Shao
Chao Ji
Bernard Gadagbui

Frontiers in Toxicology

doi 10.3389/ftox.2024.1440229

589 views

Original Research

Published on 01 Jul 2024

Evaluation of the immunotoxicity potential of nanomaterials using THP-1 cells

in Nanotoxicology

Asuka Nishida
Yuka Sawada
Rion Arai
Naoki Ishibashi
Miho Suzuo
Akiko Ohno
Takao Ashikaga
Kazutoshi Iijima

Frontiers in Toxicology

doi 10.3389/ftox.2024.1293147

830 views
2 citations

Original Research

Published on 13 Jun 2024

Optimisation of an in vitro human cardiovascular model on-a-chip for toxicological assessment of nicotine delivery products

in In Vitro Toxicology

Fiona Chapman
Luuk de Haan
Linda Gijzen
Wouter Strijker
Edgar Trelles Sticken
Sarah Jean Pour
Roman Wieczorek
Florian Haberstroh
Sandra Otte
Thomas Nahde

Frontiers in Toxicology

doi 10.3389/ftox.2024.1395670

1,982 views

Review

Published on 13 Jun 2024

Applying new approach methodologies to assess next-generation tobacco and nicotine products

in In Vitro Toxicology

David Thorne
Damian McHugh
Liam Simms
K. Monica Lee
Hitoshi Fujimoto
Sara Moses
Marianna Gaca

Frontiers in Toxicology

doi 10.3389/ftox.2024.1376118

2,473 views

Policy and Practice Reviews

Published on 12 Jun 2024

Assessing human carcinogenicity risk of agrochemicals without the rodent cancer bioassay

in Regulatory Toxicology

Amber Goetz
Natalia Ryan
Alaina Sauve-Ciencewicki
Caleb C. Lord
Gina M. Hilton
Douglas C. Wolf

Frontiers in Toxicology

doi 10.3389/ftox.2024.1394361

1,609 views

Editorial

Published on 07 Jun 2024

Editorial: Linking environmental exposure to toxicants and chronic disease

in Developmental and Reproductive Toxicology

David R. Wallace
Aleksandra Buha Đorđević

Frontiers in Toxicology

doi 10.3389/ftox.2024.1430316

680 views

Original Research

Published on 05 Jun 2024

Exposure to PFAS chemicals induces sex-dependent alterations in key rate-limiting steps of lipid metabolism in liver steatosis

in Environmental Toxicology

Archana Hari
Mohamed Diwan M. AbdulHameed
Michele R. Balik-Meisner
Deepak Mav
Dhiral P. Phadke
Elizabeth H. Scholl
Ruchir R. Shah
Warren Casey
Scott S. Auerbach
Anders Wallqvist

Frontiers in Toxicology

doi 10.3389/ftox.2024.1390196

2,042 views
1 citation

Systematic Review

Published on 30 May 2024

Does pyrethroid exposure lower human semen quality? a systematic review and meta-analysis

in Developmental and Reproductive Toxicology

Roland Eghoghosoa Akhigbe
Precious Adeoye Oyedokun
Tunmise Maryanne Akhigbe
Suliat Adenike
Ayoola Abimbola Oladipo
Jennifer Rose Hughes

Frontiers in Toxicology

doi 10.3389/ftox.2024.1395010

1,038 views
1 citation

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Articles

Transforming environmental health datasets from the comparative toxicogenomics database into chord diagrams to visualize molecular mechanisms

Safety of titanium dioxide (E171) as a food additive for humans

Corrigendum: Applying new approach methodologies to assess next-generation tobacco and nicotine products

Per- and poly-fluoroalkyl substances (PFAS) effects on lung health: a perspective on the current literature and future recommendations

Unleashing the potential of cell painting assays for compound activities and hazards prediction

Many human pharmaceuticals are weak inhibitors of the cytochrome P450 system in rainbow trout (Oncorhynchus mykiss) liver S9 fractions

sendigR: an R package to leverage the value of CDISC SEND datasets for cross-study analysis

Bioactivation of cinnamic alcohol in a reconstructed human epidermis model and evaluation of sensitizing potency of the identified metabolites

Editorial: Next generation chemical risk assessment: integration of advances in toxicology, biology and computation

Evaluation of the immunotoxicity potential of nanomaterials using THP-1 cells

Optimisation of an in vitro human cardiovascular model on-a-chip for toxicological assessment of nicotine delivery products

Applying new approach methodologies to assess next-generation tobacco and nicotine products

Assessing human carcinogenicity risk of agrochemicals without the rodent cancer bioassay

Editorial: Linking environmental exposure to toxicants and chronic disease

Exposure to PFAS chemicals induces sex-dependent alterations in key rate-limiting steps of lipid metabolism in liver steatosis

Does pyrethroid exposure lower human semen quality? a systematic review and meta-analysis