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Articles

Original Research

Published on 14 Jul 2022

A Mathematical Model for On-Target Off-Tumor Effect of CAR-T Cells on Gliomas

in Translational Systems Biology and In Silico Trials

Daniela Silva Santurio
Luciana Rodrigues Carvalho Barros

A Mathematical Model for On-Target Off-Tumor Effect of CAR-T Cells on Gliomas

Frontiers in Systems Biology

doi 10.3389/fsysb.2022.923085

2,658 views
9 citations

Perspective

Published on 20 Jun 2022

Drug Development Digital Twins for Drug Discovery, Testing and Repurposing: A Schema for Requirements and Development

in Translational Systems Biology and In Silico Trials

Gary An
Chase Cockrell

Drug Development Digital Twins for Drug Discovery, Testing and Repurposing: A Schema for Requirements and Development

Frontiers in Systems Biology

doi 10.3389/fsysb.2022.928387

7,059 views
31 citations

Specialty Grand Challenge

Published on 28 Apr 2022

Specialty Grand Challenge: What it Will Take to Cross the Valley of Death: Translational Systems Biology, “True” Precision Medicine, Medical Digital Twins, Artificial Intelligence and In Silico Clinical Trials

in Translational Systems Biology and In Silico Trials

Gary An

Specialty Grand Challenge: What it Will Take to Cross the Valley of Death: Translational Systems Biology, “True” Precision Medicine, Medical Digital Twins, Artificial Intelligence and In Silico Clinical Trials

Frontiers in Systems Biology

doi 10.3389/fsysb.2022.901159

3,051 views
7 citations