Original Research

Published on 20 Jun 2023

Using quantitative systems pharmacology modeling to optimize combination therapy of anti-PD-L1 checkpoint inhibitor and T cell engager

in Translational Pharmacology

Samira Anbari
Hanwen Wang
Yu Zhang
Jun Wang
Minu Pilvankar
Masoud Nickaeen
Steven Hansel
Aleksander S. Popel

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1163432

4,871 views
18 citations

Review

Published on 14 Jun 2023

In vitro percutaneous penetration test overview

in Translational Pharmacology

Sheeva Shahinfar
Howard Maibach

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1102433

2,579 views
1 citation

Original Research

Published on 14 Jun 2023

Network pharmacology-based approach to explore the underlying mechanism of sinomenine on sepsis-induced myocardial injury in rats

in Translational Pharmacology

Linggang Sun
Zhiyun Chen
Yunjie Ni
Zhengfei He

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1138858

2,723 views
3 citations

Original Research

Published on 13 Jun 2023

Prevalence and risk factors of upper gastrointestinal symptoms in community pharmacies in Spain: a cross-sectional study

in Translational Pharmacology

María Puig-Moltó
Blanca Lumbreras
Elsa López-Pintor

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1162370

1,689 views
2 citations

Clinical Trial

Published on 09 Jun 2023

Pharmacokinetic interaction of voriconazole and clarithromycin in Pakistani healthy male volunteers: a single dose, randomized, crossover, open-label study

in Translational Pharmacology

Mehwish Mushtaq
Kshaf Fatima
Aneeqa Ahmad
Osama Mohamed Ibrahim
Muhammad Faheem
Yasar Shah

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1134803

3,428 views
2 citations

Case Report

Published on 08 Jun 2023

Case Report: Off-label treatment of idiopathic hypereosinophilic syndrome with Omalizumab

in Translational Pharmacology

Zhiyu Zhang
Yingxin Sun
Su-Ning Chen

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1095737

2,453 views
1 citation

Review

Published on 06 Jun 2023

PARP-1: a critical regulator in radioprotection and radiotherapy-mechanisms, challenges, and therapeutic opportunities

in Translational Pharmacology

Wen-Hao Li
Fei Wang
Gui-Yuan Song
Qing-Hua Yu
Rui-Peng Du
Ping Xu

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1198948

5,429 views
6 citations

Correction

Published on 01 Jun 2023

Corrigendum: Pharmacokinetics and bioequivalence study of esomeprazole magnesium enteric-coated tablets 20 mg in healthy Chinese subjects under fasting and fed conditions

in Translational Pharmacology

Ying Ding
Nannan Chu
Linling Que
Kai Huang
Yuanxing Chen
Wei Qin
Zhenzhong Qian
Yunfei Shi
Zhen Xu
Qing He

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1217008

1,038 views

Original Research

Published on 01 Jun 2023

Mechanistic evaluation of the inhibitory effect of four SGLT-2 inhibitors on SGLT 1 and SGLT 2 using physiologically based pharmacokinetic (PBPK) modeling approaches

in Translational Pharmacology

Yu Zhang
Panpan Xie
Yamei Li
Zhixing Chen
Aixin Shi

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1142003

4,979 views
4 citations

Case Report

Published on 30 May 2023

The dilemma of antibiotic susceptibility and clinical decision-making in a multi-drug-resistant Pseudomonas aeruginosa bloodstream infection

in Translational Pharmacology

Long Chen
Xingyi Qu
Jingqian Su
Haijun Yao
Qiang Yuan
Yu Wang
Nanyang Li
Gang Wu
Xiaofen Liu
Jin Hu

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1183332

1,865 views

Original Research

Published on 22 May 2023

Estimation of dihydroartemisinin in human plasma using a highly sensitive LTQ Orbitrap mass spectrometer with Xcalibur software

in Translational Pharmacology

Tareq Abu-Izneid
Muhammad Abbas
David G. Watson
Yasar Shah
Sayyed I. Shah
Fazli Khuda

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1157604

1,654 views
2 citations

Opinion

Published on 04 May 2023

P-glycoprotein efflux transporter: a key to pharmacokinetic modeling for methadone clearance in fetuses

in Translational Pharmacology

Harvey Ho
En Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1182571

1,376 views
1 citation

Original Research

Published on 03 May 2023

Oral vinorelbine and continuous low doses of cyclophosphamide in pediatric rhabdomyosarcoma: a real-world study

in Translational Pharmacology

Yingxia Lan
Liuhong Wu
Ye Hong
Xiaofei Sun
Juan Wang
Junting Huang
Feifei Sun
Jia Zhu
Zijun Zhen
Yizhuo Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1132219

3,199 views
1 citation

Clinical Trial

Published on 28 Apr 2023

Pharmacokinetics and bioequivalence study of esomeprazole magnesium enteric-coated tablets 20 mg in healthy Chinese subjects under fasting and fed conditions

in Translational Pharmacology

Ying Ding
Nannan Chu
Linling Que
Kai Huang
Yuanxing Chen
Wei Qin
Zhenzhong Qian
Yunfei Shi
Zhen Xu
Qing He

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1169103

7,237 views

Review

Published on 25 Apr 2023

Revolutionizing drug development: harnessing the potential of organ-on-chip technology for disease modeling and drug discovery

in Translational Pharmacology

Naina Sunildutt
Pratibha Parihar
Abdul Rahim Chethikkattuveli Salih
Sang Ho Lee
Kyung Hyun Choi

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1139229

9,010 views
25 citations

Original Research

Published on 20 Apr 2023

Metformin acts as a dual glucose regulator in mouse brain

in Translational Pharmacology

Bo-Yeong Jin
Hyun-Ju Kim
Mi-Jeong Oh
Na-Hee Ha
Yong Taek Jeong
Sang-Hyun Choi
Jun-Seok Lee
Nam Hoon Kim
Dong-Hoon Kim

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1108660

2,467 views
2 citations

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Articles

Using quantitative systems pharmacology modeling to optimize combination therapy of anti-PD-L1 checkpoint inhibitor and T cell engager

In vitro percutaneous penetration test overview

Network pharmacology-based approach to explore the underlying mechanism of sinomenine on sepsis-induced myocardial injury in rats

Prevalence and risk factors of upper gastrointestinal symptoms in community pharmacies in Spain: a cross-sectional study

Pharmacokinetic interaction of voriconazole and clarithromycin in Pakistani healthy male volunteers: a single dose, randomized, crossover, open-label study

Case Report: Off-label treatment of idiopathic hypereosinophilic syndrome with Omalizumab

PARP-1: a critical regulator in radioprotection and radiotherapy-mechanisms, challenges, and therapeutic opportunities

Corrigendum: Pharmacokinetics and bioequivalence study of esomeprazole magnesium enteric-coated tablets 20 mg in healthy Chinese subjects under fasting and fed conditions

Mechanistic evaluation of the inhibitory effect of four SGLT-2 inhibitors on SGLT 1 and SGLT 2 using physiologically based pharmacokinetic (PBPK) modeling approaches

The dilemma of antibiotic susceptibility and clinical decision-making in a multi-drug-resistant Pseudomonas aeruginosa bloodstream infection

Estimation of dihydroartemisinin in human plasma using a highly sensitive LTQ Orbitrap mass spectrometer with Xcalibur software

P-glycoprotein efflux transporter: a key to pharmacokinetic modeling for methadone clearance in fetuses

Oral vinorelbine and continuous low doses of cyclophosphamide in pediatric rhabdomyosarcoma: a real-world study

Pharmacokinetics and bioequivalence study of esomeprazole magnesium enteric-coated tablets 20 mg in healthy Chinese subjects under fasting and fed conditions

Revolutionizing drug development: harnessing the potential of organ-on-chip technology for disease modeling and drug discovery

Metformin acts as a dual glucose regulator in mouse brain