Frontiers in Pharmacology | Translational Pharmacology

Original Research

Published on 18 Oct 2024

Proteomic study of medicinal mushroom extracts reveals antitumor mechanisms in an advanced colon cancer animal model via ribosomal biogenesis, translation, and metabolic pathways

in Translational Pharmacology

Boris Jakopovic
Anita Horvatić
Jurica Baranasic
Iris Car
Nada Oršolić
Ivan Jakopovich
Mirela Sedić
Sandra Kraljević Pavelić

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1475102

2,221 views

Original Research

Published on 17 Oct 2024

Drug selection for inner ear therapy

in Translational Pharmacology

Alec N. Salt
Jeremy G. Turner

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1452927

1,435 views
1 citation

Original Research

Published on 09 Oct 2024

Formulation development, characterization, and evaluation of sorafenib-loaded PLGA–chitosan nanoparticles

in Translational Pharmacology

Abdul Mateen
Abad Khan
Ismail Khan
Lateef Ahmad
Amjad Khan
Abdul Salam

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1465363

1,222 views

Original Research

Published on 07 Oct 2024

Diacerein reduces inflammasome activation and SARS-CoV-2 virus replication: a proof-of-concept translational study

in Translational Pharmacology

Helison R. P. Carmo
Alejandro Rossel Castillo
Isabella Bonilha
Erica I. L. Gomes
Joaquim Barreto
Filipe A. Moura
Gustavo Gastão Davanzo
Lauar de Brito Monteiro
Stéfanie Primon Muraro
Gabriela Fabiano de Souza

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1402032

2,458 views
1 citation

Review

Published on 01 Oct 2024

The versatile multi-functional substance NMN: its unique characteristics, metabolic properties, pharmacodynamic effects, clinical trials, and diverse applications

in Translational Pharmacology

Bin Yu
Xiaotong Jing
Lina Jia
Maoru Wang
Liying Liu
Songyuge Ping
Yu Wang
Min Yang

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1436597

7,273 views
1 citation

Review

Published on 25 Sep 2024

Hydrogel-based formulations for urothelial cancer therapy

in Translational Pharmacology

Mingyang Chang
Changliang Chi
Zuozhu Zheng
Ming Zhang
Jianing Lv
Xiaoqing Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1478394

1,560 views

Editorial

Published on 20 Sep 2024

Editorial: Molecular targets in oncological and hematological disease management: innovations in precision medicine

in Translational Pharmacology

Adrian Bogdan Tigu
Gregory Wiedman
Stefan Eugen Szedlacsek

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1494396

571 views

Original Research

Published on 20 Sep 2024

A quantitative systems pharmacology (QSP) platform for preclinical to clinical translation of in-vivo CRISPR-Cas therapy

in Translational Pharmacology

Devam A. Desai
Stephan Schmidt
Rodrigo Cristofoletti

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1454785

3,423 views
1 citation

Original Research

Published on 19 Sep 2024

Optimizing tacrolimus dosing in Hispanic renal transplant patients: insights from real-world data

in Translational Pharmacology

Athanasios Chamzas
Eglis Tellez
Andrew SyBing
Jogarao V. S. Gobburu
Mathangi Gopalakrishnan

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1443988

952 views

Original Research

Published on 04 Sep 2024

Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) may reduce the risk of developing cancer-related lymphedema following axillary lymph node dissection (ALND)

in Translational Pharmacology

Stav Brown
Audree B. Tadros
Giacomo Montagna
Tajah Bell
Fionnuala Crowley
Emily J. Gallagher
Joseph H. Dayan

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1457363

5,210 views

Original Research

Published on 02 Sep 2024

Unveiling novel serum biomarkers in intrahepatic cholangiocarcinoma: a pilot proteomic exploration

in Translational Pharmacology

Lavinia Patricia Mocan
Cristiana Grapa
Rareș Crăciun
Ioana Ecaterina Pralea
Alina Uifălean
Andreea Maria Soporan
Ximena Maria Mureșan
Maria Iacobescu
Nadim Al Hajjar
Carmen Mihaela Mihu

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1440985

1,945 views
1 citation

Original Research

Published on 30 Aug 2024

The epigenetic signatures of opioid addiction and physical dependence are prevented by D-cysteine ethyl ester and betaine

in Translational Pharmacology

Jennifer McDonough
Naveen K. Singhal
Paulina M. Getsy
Katherine Knies
Zackery T. Knauss
Devin Mueller
James N. Bates
Derek S. Damron
Stephen J. Lewis

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1416701

1,559 views
2 citations

Review

Published on 28 Aug 2024

Advances in research on potential therapeutic approaches for Niemann-Pick C1 disease

in Translational Pharmacology

Caifeng Zhang
Keke Su
Xu Jiang
Yuping Tian
Ke Li

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1465872

2,328 views
1 citation

Clinical Trial

Published on 22 Aug 2024

Pharmacokinetics and safety profiles of beinaglutide injection, a recombinant human GLP-1, in adults with overweight/obesity: results from a phase I clinical trial

in Translational Pharmacology

Pingping Lin
Chengqian Li
Yanping Liu
Feifei Sun
Tsung-Han Hsieh
Lin Zhang
Yaping Ma
Xiaomeng Gao
Qing Yu
Yu Cao

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1433587

1,792 views

Original Research

Published on 20 Aug 2024

In vitro evidence of antioxidant and anti-inflammatory effects of a new nutraceutical formulation explains benefits in a clinical setting of COPD patients

in Translational Pharmacology

Valentina Lazzara
Paola Pinto
Serena Di Vincenzo
Maria Ferraro
Filippo Catalano
Pietro Provinzano
Elisabetta Pace
Maria Rosaria Bonsignore

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1439835

1,508 views
1 citation

Original Research

Published on 16 Aug 2024

The GLP-1 receptor agonist exendin-4 reduces taurine and glycine in nucleus accumbens of male rats, an effect tentatively involving the nucleus tractus solitarius

in Translational Pharmacology

Christian E. Edvardsson
Jesper Vestlund
Mia Ericson
Elisabet Jerlhag

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1439203

1,860 views
1 citation