Original Research

Published on 07 Mar 2022

Gut Microbiota-Mediated Elevated Production of Secondary Bile Acids in Chronic Unpredictable Mild Stress

in Translational Pharmacology

Yuchen Qu
Cunjin Su
Qinhong Zhao
Aiming Shi
Fenglun Zhao
Liuxing Tang
Delai Xu
Zheng Xiang
Yang Wang
Yueyuan Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2022.837543

5,054 views
22 citations

Original Research

Published on 07 Mar 2022

Lipidated Calcitonin Gene-Related Peptide (CGRP) Peptide Antagonists Retain CGRP Receptor Activity and Attenuate CGRP Action In Vivo

in Translational Pharmacology

Aqfan Jamaluddin
Chia-Lin Chuang
Elyse T. Williams
Andrew Siow
Sung Hyun Yang
Paul W. R. Harris
Jakeb S. S. M. Petersen
Rebekah L. Bower
Shanan Chand
Margaret A. Brimble

Frontiers in Pharmacology

doi 10.3389/fphar.2022.832589

4,464 views
9 citations

Original Research

Published on 07 Mar 2022

Efficacy and Safety of Neostigmine Adjunctive Therapy in Patients With Sepsis or Septic Shock: A Randomized Controlled Trial

in Translational Pharmacology

Mona M. El-Tamalawy
Moetaza M. Soliman
Amany F. Omara
Amal Rashad
Osama M. Ibrahim
Mamdouh M. El-Shishtawy

Frontiers in Pharmacology

doi 10.3389/fphar.2022.855764

2,862 views
1 citation

Original Research

Published on 04 Mar 2022

Beneficial Metabolic Effects of Praliciguat, a Soluble Guanylate Cyclase Stimulator, in a Mouse Diet-Induced Obesity Model

in Translational Pharmacology

Chad D. Schwartzkopf
John R. Hadcock
Guang Liu
Peter Germano
Julien Roux
Courtney M. Shea
Emmanuel S. Buys
Juli E. Jones

Frontiers in Pharmacology

doi 10.3389/fphar.2022.852080

3,184 views
2 citations

Original Research

Published on 04 Mar 2022

FGF4, A New Potential Regulator in Gestational Diabetes Mellitus

in Translational Pharmacology

Miaojuan Fan
Tongtong Pan
Wei Jin
Jian Sun
Shujun Zhang
Yali Du
Xinwei Chen
Qiong Chen
Wenxin Xu
Siew Woh Choo

Frontiers in Pharmacology

doi 10.3389/fphar.2022.827617

3,747 views
5 citations

Original Research

Published on 04 Mar 2022

Pharmacokinetics, Pharmacodynamics, Safety, Tolerability, and Immunogenicity of the QX002N anti-IL-17 Monoclonal Antibody: A Phase I, Randomized, Double-Blind, Single Ascending Dose Study in Healthy Chinese Volunteers

in Translational Pharmacology

Min Wu
Hong Zhang
Qianqian Li
Hong Chen
Min Fang
Lizhi Yang
Yanhua Ding

Frontiers in Pharmacology

doi 10.3389/fphar.2021.794054

3,082 views
2 citations

Editorial

Published on 02 Mar 2022

Editorial: Intranasal Drug Delivery: Challenges and Opportunities

in Translational Pharmacology

Ana Fortuna
Katharina Schindowski
Fabio Sonvico

Frontiers in Pharmacology

doi 10.3389/fphar.2022.868986

8,701 views
9 citations

Correction

Published on 25 Feb 2022

Corrigendum: TNF-α in Uveitis: From Bench to Clinic

in Translational Pharmacology

Qi Jiang
Zhaohuai Li
Tianyu Tao
Runping Duan
Xianggui Wang
Wenru Su

Frontiers in Pharmacology

doi 10.3389/fphar.2022.817235

1,736 views
2 citations

Original Research

Published on 22 Feb 2022

Development of a Definition for Medical Affairs Using the Jandhyala Method for Observing Consensus Opinion Among Medical Affairs Pharmaceutical Physicians

in Translational Pharmacology

Ravi Jandhyala

Frontiers in Pharmacology

doi 10.3389/fphar.2022.842431

3,813 views
7 citations

Original Research

Published on 22 Feb 2022

Carotid Intraplaque Neovascularization and Future Vascular Events in Patients With Asymptomatic Carotid Stenosis

in Translational Pharmacology

Liuping Cui
Yingqi Xing
Lijuan Wang
Kangding Liu
Hongxiu Chen
Cong Li
Ying Chen

Frontiers in Pharmacology

doi 10.3389/fphar.2022.804810

2,443 views
13 citations

Original Research

Published on 21 Feb 2022

Discovery of Novel and Highly Potent Inhibitors of SARS CoV-2 Papain-Like Protease Through Structure-Based Pharmacophore Modeling, Virtual Screening, Molecular Docking, Molecular Dynamics Simulations, and Biological Evaluation

in Translational Pharmacology

Xiaoyan Tian
Quanfeng Zhao
Xiaohong Chen
Zhe Peng
Xiaodan Tan
Qin Wang
Lin Chen
Yang Yang

Frontiers in Pharmacology

doi 10.3389/fphar.2022.817715

3,626 views
9 citations

Mini Review

Published on 21 Feb 2022

Molecular Docking as a Therapeutic Approach for Targeting Cancer Stem Cell Metabolic Processes

in Translational Pharmacology

Babak Arjmand
Shayesteh Kokabi Hamidpour
Sepideh Alavi-Moghadam
Hanieh Yavari
Ainaz Shahbazbadr
Mostafa Rezaei Tavirani
Kambiz Gilany
Bagher Larijani

Frontiers in Pharmacology

doi 10.3389/fphar.2022.768556

14,520 views
27 citations

Original Research

Published on 21 Feb 2022

The Bioflavonoids Rutin and Rutin Succinate Neutralize the Toxins of B. jararaca Venom and Inhibit its Lethality

in Translational Pharmacology

Ana Teresa Azevedo Sachetto
Jackson Gabriel Miyamoto
Alexandre Keiji Tashima
Ana Olívia de Souza
Marcelo Larami Santoro

Frontiers in Pharmacology

doi 10.3389/fphar.2022.828269

6,296 views
5 citations

Review

Published on 18 Feb 2022

Tocilizumab and COVID-19: Timing of Administration and Efficacy

in Translational Pharmacology

Emna Abidi
Wasim S. El Nekidy
Eman Alefishat
Nadeem Rahman
Georg A. Petroianu
Rania El-Lababidi
Jihad Mallat

Frontiers in Pharmacology

doi 10.3389/fphar.2022.825749

9,521 views
38 citations

Original Research

Published on 15 Feb 2022

Chronic Administration of Cannabinoid Receptor 2 Agonist (JWH-133) Increases Ectopic Ovarian Tumor Growth and Endocannabinoids (Anandamide and 2-Arachidonoyl Glycerol) Levels in Immunocompromised SCID Female Mice

in Translational Pharmacology

Henry L. Blanton
Melissa C. McHann
Haley De Selle
Canice Lei Dancel
Jose-Luis Redondo
Deborah Molehin
Nadezhda A. German
Scott Trasti
Kevin Pruitt
Isabel Castro-Piedras

Frontiers in Pharmacology

doi 10.3389/fphar.2022.823132

3,218 views
3 citations

Original Research

Published on 14 Feb 2022

SPHK Inhibitors and Zoledronic Acid Suppress Osteoclastogenesis and Wear Particle-Induced Osteolysis

in Translational Pharmacology

Minghui Gu
Baiqi Pan
Weishen Chen
Hai Xu
Xiaoyu Wu
Xuantao Hu
Linli Zheng
Yongyu Ye
Qing Meng
Guoyan Xian

Frontiers in Pharmacology

doi 10.3389/fphar.2021.794429

3,369 views
4 citations

Navigation group

Articles

Gut Microbiota-Mediated Elevated Production of Secondary Bile Acids in Chronic Unpredictable Mild Stress

Lipidated Calcitonin Gene-Related Peptide (CGRP) Peptide Antagonists Retain CGRP Receptor Activity and Attenuate CGRP Action In Vivo

Efficacy and Safety of Neostigmine Adjunctive Therapy in Patients With Sepsis or Septic Shock: A Randomized Controlled Trial

Beneficial Metabolic Effects of Praliciguat, a Soluble Guanylate Cyclase Stimulator, in a Mouse Diet-Induced Obesity Model

FGF4, A New Potential Regulator in Gestational Diabetes Mellitus

Pharmacokinetics, Pharmacodynamics, Safety, Tolerability, and Immunogenicity of the QX002N anti-IL-17 Monoclonal Antibody: A Phase I, Randomized, Double-Blind, Single Ascending Dose Study in Healthy Chinese Volunteers

Editorial: Intranasal Drug Delivery: Challenges and Opportunities

Corrigendum: TNF-α in Uveitis: From Bench to Clinic

Development of a Definition for Medical Affairs Using the Jandhyala Method for Observing Consensus Opinion Among Medical Affairs Pharmaceutical Physicians

Carotid Intraplaque Neovascularization and Future Vascular Events in Patients With Asymptomatic Carotid Stenosis

Discovery of Novel and Highly Potent Inhibitors of SARS CoV-2 Papain-Like Protease Through Structure-Based Pharmacophore Modeling, Virtual Screening, Molecular Docking, Molecular Dynamics Simulations, and Biological Evaluation

Molecular Docking as a Therapeutic Approach for Targeting Cancer Stem Cell Metabolic Processes

The Bioflavonoids Rutin and Rutin Succinate Neutralize the Toxins of B. jararaca Venom and Inhibit its Lethality

Tocilizumab and COVID-19: Timing of Administration and Efficacy

Chronic Administration of Cannabinoid Receptor 2 Agonist (JWH-133) Increases Ectopic Ovarian Tumor Growth and Endocannabinoids (Anandamide and 2-Arachidonoyl Glycerol) Levels in Immunocompromised SCID Female Mice

SPHK Inhibitors and Zoledronic Acid Suppress Osteoclastogenesis and Wear Particle-Induced Osteolysis