Original Research

Accepted on 13 Nov 2024

Network pharmacology, experimental validation and pharmacokinetics integrated strategy to reveal pharmacological mechanism of Goutengsan on methamphetamine dependence

in Translational Pharmacology

Han-cheng Li
Jie-Yu Li
Xing-Chen Wang
Ming Zeng
Yang-Kai Wu
Yi-Ling Chen
Cai-Hua Kong
Ke-Lin Chen
Jie-Ru Wu
Zhi-Xian Mo

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1480562

Original Research

Published on 13 Nov 2024

Inhibition of CISD2 enhances sensitivity to doxorubicin in diffuse large B-cell lymphoma by regulating ferroptosis and ferritinophagy

in Translational Pharmacology

Chaofeng Zhang
Siting Zhan
Yanjun He
Zhiqun Pan
Zhongyi You
Xiongpeng Zhu
Qi Lin

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1482354

128 views

Mini Review

Accepted on 11 Nov 2024

Modeling Development of Breast Cancer: from Tumor Microenvironment to Preclinical Applications

in Translational Pharmacology

Ruizhi Tang
Xi-Qiu Liu

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1466017

Original Research

Published on 11 Nov 2024

Treatment of chronic osteomyelitis with gradient release of DGEA and vancomycin hydrogel-microsphere system and its mechanism

in Translational Pharmacology

Yuhao Zheng
Yue Wang
Fan Sheng
Shu Wang
Ying Zhou
Xiaoxu Li
Ning Li
Wenling Song
Zhiming Song

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1499742

150 views

Original Research

Published on 07 Nov 2024

Elusive elapids: biogeographic venom variation in Indian kraits and its repercussion on snakebite therapy

in Translational Pharmacology

U. Rashmi
Siddharth Bhatia
Muralidhar Nayak
Suyog Khochare
Kartik Sunagar

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1443073

799 views

Original Research

Accepted on 06 Nov 2024

Supplementation of dipeptide alanine-glutamine ameliorates retinal neurodegeneration in an STZ-induced rat model

in Translational Pharmacology

Qian Chen
Yuhan Zhang
Mingyan Wei
Xin Wang
Yuan Xu
Rongrong zong
Xiang Lin
ShiYing Li
Wensheng Chen
Zuguo Liu

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1490443

Original Research

Published on 29 Oct 2024

Biogenically synthesized gold nanocarrier ameliorated antiproliferative and apoptotic efficacy of doxorubicin against lung cancer

in Translational Pharmacology

Yazeed Albulaihed
Prakriti Mishra
Mohd Saeed
Nadiyah M. Alabdallah
Tarig Ginawi
Irfan Ahmad Ansari

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1438237

321 views

Original Research

Published on 24 Oct 2024

pH-sensitive supramolecular self-assembled peptide hydrogel for the treatment of esophageal cancer

in Translational Pharmacology

Gaobing Ye
Shiyao Luo
Hajra Zafar
Honglei Ge
Binbin Liu
Nan Wang
Yu Jin
Miao Wang
Xu Chen
Xiaoming Ye

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1453422

324 views

Review

Published on 23 Oct 2024

Composition of lipid nanoparticles for targeted delivery: application to mRNA therapeutics

in Translational Pharmacology

Olga Vasileva
Olga Zaborova
Bogdan Shmykov
Roman Ivanov
Vasiliy Reshetnikov

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1466337

1,238 views

Review

Published on 22 Oct 2024

New insights into the roles of lactylation in cancer

in Translational Pharmacology

Yajun Zhu
Wenhui Liu
Zhiying Luo
Feiyan Xiao
Bao Sun

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1412672

494 views

Original Research

Published on 18 Oct 2024

Proteomic study of medicinal mushroom extracts reveals antitumor mechanisms in an advanced colon cancer animal model via ribosomal biogenesis, translation, and metabolic pathways

in Translational Pharmacology

Boris Jakopovic
Anita Horvatić
Jurica Baranasic
Iris Car
Nada Oršolić
Ivan Jakopovich
Mirela Sedić
Sandra Kraljević Pavelić

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1475102

1,018 views

Original Research

Published on 17 Oct 2024

Drug selection for inner ear therapy

in Translational Pharmacology

Alec N. Salt
Jeremy G. Turner

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1452927

512 views

Original Research

Published on 09 Oct 2024

Formulation development, characterization, and evaluation of sorafenib-loaded PLGA–chitosan nanoparticles

in Translational Pharmacology

Abdul Mateen
Abad Khan
Ismail Khan
Lateef Ahmad
Amjad Khan
Abdul Salam

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1465363

494 views

Original Research

Published on 07 Oct 2024

Diacerein reduces inflammasome activation and SARS-CoV-2 virus replication: a proof-of-concept translational study

in Translational Pharmacology

Helison R. P. Carmo
Alejandro Rossel Castillo
Isabella Bonilha
Erica I. L. Gomes
Joaquim Barreto
Filipe A. Moura
Gustavo Gastão Davanzo
Lauar de Brito Monteiro
Stéfanie Primon Muraro
Gabriela Fabiano de Souza

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1402032

996 views

Review

Published on 01 Oct 2024

The versatile multi-functional substance NMN: its unique characteristics, metabolic properties, pharmacodynamic effects, clinical trials, and diverse applications

in Translational Pharmacology

Bin Yu
Xiaotong Jing
Lina Jia
Maoru Wang
Liying Liu
Songyuge Ping
Yu Wang
Min Yang

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1436597

1,317 views

Review

Published on 25 Sep 2024

Hydrogel-based formulations for urothelial cancer therapy

in Translational Pharmacology

Mingyang Chang
Changliang Chi
Zuozhu Zheng
Ming Zhang
Jianing Lv
Xiaoqing Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1478394

693 views

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Articles

Network pharmacology, experimental validation and pharmacokinetics integrated strategy to reveal pharmacological mechanism of Goutengsan on methamphetamine dependence

Inhibition of CISD2 enhances sensitivity to doxorubicin in diffuse large B-cell lymphoma by regulating ferroptosis and ferritinophagy

Modeling Development of Breast Cancer: from Tumor Microenvironment to Preclinical Applications

Treatment of chronic osteomyelitis with gradient release of DGEA and vancomycin hydrogel-microsphere system and its mechanism

Elusive elapids: biogeographic venom variation in Indian kraits and its repercussion on snakebite therapy

Supplementation of dipeptide alanine-glutamine ameliorates retinal neurodegeneration in an STZ-induced rat model

Biogenically synthesized gold nanocarrier ameliorated antiproliferative and apoptotic efficacy of doxorubicin against lung cancer

pH-sensitive supramolecular self-assembled peptide hydrogel for the treatment of esophageal cancer

Composition of lipid nanoparticles for targeted delivery: application to mRNA therapeutics

New insights into the roles of lactylation in cancer

Proteomic study of medicinal mushroom extracts reveals antitumor mechanisms in an advanced colon cancer animal model via ribosomal biogenesis, translation, and metabolic pathways

Drug selection for inner ear therapy

Formulation development, characterization, and evaluation of sorafenib-loaded PLGA–chitosan nanoparticles

Diacerein reduces inflammasome activation and SARS-CoV-2 virus replication: a proof-of-concept translational study

The versatile multi-functional substance NMN: its unique characteristics, metabolic properties, pharmacodynamic effects, clinical trials, and diverse applications

Hydrogel-based formulations for urothelial cancer therapy