Review

Published on 16 Aug 2021

Targeting the Wnt/β-Catenin Signaling Pathway as a Potential Therapeutic Strategy in Renal Tubulointerstitial Fibrosis

in Renal Pharmacology

Shan-Shan Li
Qian Sun
Meng-Ru Hua
Ping Suo
Jia-Rong Chen
Xiao-Yong Yu
Ying-Yong Zhao

Frontiers in Pharmacology

doi 10.3389/fphar.2021.719880

9,959 views
76 citations

Systematic Review

Published on 03 Aug 2021

Effectiveness of Drug Treatments for Lowering Uric Acid on Renal Function in Patients With Chronic Kidney Disease and Hyperuricemia: A Network Meta-Analysis of Randomized Controlled Trials

in Renal Pharmacology

Xiang Liu
Yuxuan Qiu
Duohui Li
Jiaxing Tan
Xiuping Liang
Wei Qin

Frontiers in Pharmacology

doi 10.3389/fphar.2021.690557

7,444 views
14 citations

Original Research

Published on 29 Jul 2021

Glomerular Damage in Trichloroethylene-Sensitized Mice: Targeting Cathepsin L-Induced Hyperactive mTOR Signaling

in Renal Pharmacology

Feng Wang
Yuying Dai
Meng Huang
Chenchen Zhang
Liping Huang
Hui Wang
Liangping Ye
Qifeng Wu
Xuejun Zhang
Qixing Zhu

Frontiers in Pharmacology

doi 10.3389/fphar.2021.639878

2,755 views
7 citations

Editorial

Published on 26 Jul 2021

Editorial: Premature Aging and Senescence in Renal Fibrosis

in Renal Pharmacology

Rohan Samarakoon
Paul J. Higgins

Frontiers in Pharmacology

doi 10.3389/fphar.2021.734892

3,302 views
1 citation

Original Research

Published on 26 Jul 2021

Modified Huangqi Chifeng Decoction Attenuates Proteinuria by Reducing Podocyte Injury in a Rat Model of Immunoglobulin a Nephropathy

in Renal Pharmacology

Meiying Chang
Bin Yang
Liusheng Li
Yuan Si
Mingming Zhao
Wei Hao
Jinning Zhao
Yu Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2021.714584

3,829 views
11 citations

Original Research

Published on 26 Jul 2021

Efficacy of AST-120 for Patients With Chronic Kidney Disease: A Network Meta-Analysis of Randomized Controlled Trials

in Renal Pharmacology

Pei-Yu Su
Ya-Han Lee
Li-Na Kuo
Yen-Cheng Chen
Chiehfeng Chen
Yi-No Kang
Elizabeth H. Chang

Frontiers in Pharmacology

doi 10.3389/fphar.2021.676345

9,835 views
17 citations

Systematic Review

Published on 20 Jul 2021

The Impact of Angiotensin-Converting Enzyme Inhibitors or Angiotensin II Receptor Blockers on Clinical Outcomes of Acute Kidney Disease Patients: A Systematic Review and Meta-Analysis

in Renal Pharmacology

Jui-Yi Chen
I-Jung Tsai
Heng-Chih Pan
Hung-Wei Liao
Javier A. Neyra
Vin-Cent Wu
Jeff S. Chueh

Frontiers in Pharmacology

doi 10.3389/fphar.2021.665250

14,190 views
20 citations

Systematic Review

Published on 19 Jul 2021

Canagliflozin for Prevention of Cardiovascular and Renal Outcomes in type2 Diabetes: A Systematic Review and Meta-analysis of Randomized Controlled Trials

in Renal Pharmacology

Lei Tian
Yuzi Cai
Huijuan Zheng
Sinan Ai
Mengqi Zhou
Qian Luo
Jingyi Tang
Weijing Liu
Yaoxian Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2021.691878

5,080 views
10 citations

Original Research

Published on 15 Jul 2021

Total Flavones of Abelmoschus manihot Ameliorates Podocyte Pyroptosis and Injury in High Glucose Conditions by Targeting METTL3-Dependent m6A Modification-Mediated NLRP3-Inflammasome Activation and PTEN/PI3K/Akt Signaling

in Renal Pharmacology

Bu-Hui Liu
Yue Tu
Guang-Xia Ni
Jin Yan
Liang Yue
Zi-Lin Li
Jing-Jing Wu
Yu-Ting Cao
Zi-Yue Wan
Wei Sun

Frontiers in Pharmacology

doi 10.3389/fphar.2021.667644

16,439 views
77 citations

Systematic Review

Published on 14 Jul 2021

Function of Uric Acid Transporters and Their Inhibitors in Hyperuricaemia

in Renal Pharmacology

Hao-lu Sun
Yi-wan Wu
He-ge Bian
Hui Yang
Heng Wang
Xiao-ming Meng
Juan Jin

Frontiers in Pharmacology

doi 10.3389/fphar.2021.667753

22,326 views
42 citations

Editorial

Published on 08 Jul 2021

Editorial: Combating Diabetes and Diabetic Kidney Disease

in Renal Pharmacology

Swayam Prakash Srivastava
Keizo Kanasaki
Julie E. Goodwin

Frontiers in Pharmacology

doi 10.3389/fphar.2021.716029

2,405 views
5 citations

Systematic Review

Published on 02 Jul 2021

Safe and Effective Treatment for Anemic Patients With Chronic Kidney Disease: An Updated Systematic Review and Meta-Analysis on Roxadustat

in Renal Pharmacology

Mei Tang
Changyu Zhu
Ting Yan
Yanglin Zhou
Qin Lv
Junlan Chuan

Frontiers in Pharmacology

doi 10.3389/fphar.2021.658079

8,610 views
16 citations

Brief Research Report

Published on 02 Jul 2021

Remdesivir Inhibits Tubulointerstitial Fibrosis in Obstructed Kidneys

in Renal Pharmacology

Lin Xu
Bo Tan
Di Huang
Meijie Yuan
Tingting Li
Ming Wu
Chaoyang Ye

Frontiers in Pharmacology

doi 10.3389/fphar.2021.626510

5,091 views
16 citations

Original Research

Published on 24 Jun 2021

The Non-Steroidal Mineralocorticoid Receptor Antagonist KBP-5074 Limits Albuminuria and has Improved Therapeutic Index Compared With Eplerenone in a Rat Model With Mineralocorticoid-Induced Renal Injury

in Renal Pharmacology

Frédéric Jaisser
Xiaojuan Tan
Shuangshuang Chi
Jinrong Liu
Ping Wang
Mark Bush
Vincent Benn
Y. Fred Yang
Jay Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2021.604928

4,858 views
15 citations

Original Research

Published on 24 Jun 2021

Nephroprotective Effects of Tetramethylpyrazine Nitrone TBN in Diabetic Kidney Disease

in Renal Pharmacology

Mei Jing
Yun Cen
Fangfang Gao
Ting Wang
Jinxin Jiang
Qianqian Jian
Liangmiao Wu
Baojian Guo
Fangcheng Luo
Gaoxiao Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2021.680336

4,641 views
15 citations

Original Research

Published on 22 Jun 2021

Acute Kidney Injury is Aggravated in Aged Mice by the Exacerbation of Proinflammatory Processes

in Renal Pharmacology

Laura Marquez-Exposito
Lucia Tejedor-Santamaria
Laura Santos-Sanchez
Floris A. Valentijn
Elena Cantero-Navarro
Sandra Rayego-Mateos
Raul R. Rodrigues-Diez
Antonio Tejera-Muñoz
Vanessa Marchant
Ana B. Sanz

Frontiers in Pharmacology

doi 10.3389/fphar.2021.662020

12,076 views
23 citations

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Articles

Targeting the Wnt/β-Catenin Signaling Pathway as a Potential Therapeutic Strategy in Renal Tubulointerstitial Fibrosis

Effectiveness of Drug Treatments for Lowering Uric Acid on Renal Function in Patients With Chronic Kidney Disease and Hyperuricemia: A Network Meta-Analysis of Randomized Controlled Trials

Glomerular Damage in Trichloroethylene-Sensitized Mice: Targeting Cathepsin L-Induced Hyperactive mTOR Signaling

Editorial: Premature Aging and Senescence in Renal Fibrosis

Modified Huangqi Chifeng Decoction Attenuates Proteinuria by Reducing Podocyte Injury in a Rat Model of Immunoglobulin a Nephropathy

Efficacy of AST-120 for Patients With Chronic Kidney Disease: A Network Meta-Analysis of Randomized Controlled Trials

The Impact of Angiotensin-Converting Enzyme Inhibitors or Angiotensin II Receptor Blockers on Clinical Outcomes of Acute Kidney Disease Patients: A Systematic Review and Meta-Analysis

Canagliflozin for Prevention of Cardiovascular and Renal Outcomes in type2 Diabetes: A Systematic Review and Meta-analysis of Randomized Controlled Trials

Total Flavones of Abelmoschus manihot Ameliorates Podocyte Pyroptosis and Injury in High Glucose Conditions by Targeting METTL3-Dependent m6A Modification-Mediated NLRP3-Inflammasome Activation and PTEN/PI3K/Akt Signaling

Function of Uric Acid Transporters and Their Inhibitors in Hyperuricaemia

Editorial: Combating Diabetes and Diabetic Kidney Disease

Safe and Effective Treatment for Anemic Patients With Chronic Kidney Disease: An Updated Systematic Review and Meta-Analysis on Roxadustat

Remdesivir Inhibits Tubulointerstitial Fibrosis in Obstructed Kidneys

The Non-Steroidal Mineralocorticoid Receptor Antagonist KBP-5074 Limits Albuminuria and has Improved Therapeutic Index Compared With Eplerenone in a Rat Model With Mineralocorticoid-Induced Renal Injury

Nephroprotective Effects of Tetramethylpyrazine Nitrone TBN in Diabetic Kidney Disease

Acute Kidney Injury is Aggravated in Aged Mice by the Exacerbation of Proinflammatory Processes