Frontiers in Pharmacology | Predictive Toxicology

Review

Published on 16 Apr 2020

Toxicomicrobiomics: The Human Microbiome vs. Pharmaceutical, Dietary, and Environmental Xenobiotics

in Predictive Toxicology

Nehal Adel Abdelsalam
Ahmed Tarek Ramadan
Marwa Tarek ElRakaiby
Ramy Karam Aziz

Frontiers in Pharmacology

doi 10.3389/fphar.2020.00390

25,421 views
85 citations

Original Research

Published on 31 Mar 2020

Real-Ambient Particulate Matter Exposure-Induced Cardiotoxicity in C57/B6 Mice

in Predictive Toxicology

Lianhua Cui
Limei Shi
Daochuan Li
Xiaobo Li
Xuan Su
Liping Chen
Qixiao Jiang
Menghui Jiang
Jing Luo
Andong Ji

Frontiers in Pharmacology

doi 10.3389/fphar.2020.00199

7,240 views
31 citations

Original Research

Published on 06 Mar 2020

Dose- and Time-Dependent Cytotoxicity of Carteolol in Corneal Endothelial Cells and the Underlying Mechanisms

in Predictive Toxicology

Wen Su
Jun Zhao
Ting-Jun Fan

Frontiers in Pharmacology

doi 10.3389/fphar.2020.00202

5,796 views
12 citations

Original Research

Published on 27 Feb 2020

ZnO Quantum Dots Induced Oxidative Stress and Apoptosis in HeLa and HEK-293T Cell Lines

in Predictive Toxicology

Yanjie Yang
Zhenhua Song
Weixia Wu
Ao Xu
Shuangyu Lv
Shaoping Ji

Frontiers in Pharmacology

doi 10.3389/fphar.2020.00131

5,935 views
44 citations

Original Research

Published on 20 Feb 2020

New Insights About Doxorubicin-Induced Toxicity to Cardiomyoblast-Derived H9C2 Cells and Dexrazoxane Cytoprotective Effect: Contribution of In Vitro1H-NMR Metabonomics

in Predictive Toxicology

Matthieu Dallons
Corentin Schepkens
Aurélie Dupuis
Vanessa Tagliatti
Jean-Marie Colet

Frontiers in Pharmacology

doi 10.3389/fphar.2020.00079

8,027 views
36 citations

Original Research

Published on 14 Feb 2020

Development of Prediction Models for Drug-Induced Cholestasis, Cirrhosis, Hepatitis, and Steatosis Based on Drug and Drug Metabolite Structures

in Predictive Toxicology

Hyun Kil Shin
Myung-Gyun Kang
Daeui Park
Tamina Park
Seokjoo Yoon

Frontiers in Pharmacology

doi 10.3389/fphar.2020.00067

6,191 views
17 citations

Original Research

Published on 31 Jan 2020

Protein Kinase D1 (PKD1) Is a New Functional Non-Genomic Target of Bisphenol A in Breast Cancer Cells

in Predictive Toxicology

Messaouda Merzoug-Larabi
Ilige Youssef
Ai Thu Bui
Christine Legay
Sophia Loiodice
Sophie Lognon
Sylvie Babajko
Jean-Marc Ricort

Frontiers in Pharmacology

doi 10.3389/fphar.2019.01683

3,800 views
6 citations

Original Research

Published on 10 Jan 2020

Doxorubicin Induces Endotheliotoxicity and Mitochondrial Dysfunction via ROS/eNOS/NO Pathway

in Predictive Toxicology

Huan He
Liang Wang
Yang Qiao
Qing Zhou
Hongwei Li
Shuping Chen
Dong Yin
Qing Huang
Ming He

Frontiers in Pharmacology

doi 10.3389/fphar.2019.01531

13,345 views
107 citations

Original Research

Published on 08 Jan 2020

Narrowing the Gap Between In Vitro and In Vivo Genetic Profiles by Deconvoluting Toxicogenomic Data In Silico

in Predictive Toxicology

Yuan Liu
Runyu Jing
Zhining Wen
Menglong Li

Frontiers in Pharmacology

doi 10.3389/fphar.2019.01489

4,239 views
9 citations

Perspective

Published on 10 Dec 2019

In Vitro Research Reproducibility: Keeping Up High Standards

in Predictive Toxicology

Cordula Hirsch
Stefan Schildknecht

Frontiers in Pharmacology

doi 10.3389/fphar.2019.01484

24,599 views
120 citations

Original Research

Published on 29 Nov 2019

Development, Testing, Parameterization, and Calibration of a Human Physiologically Based Pharmacokinetic Model for the Plasticizer, Hexamoll® Diisononyl-Cyclohexane-1, 2-Dicarboxylate Using In Silico, In Vitro, and Human Biomonitoring Data

in Predictive Toxicology

Kevin McNally
Craig Sams
George Loizou

Frontiers in Pharmacology

doi 10.3389/fphar.2019.01394

3,817 views
11 citations

Original Research

Published on 26 Nov 2019

Additive Dose Response Models: Defining Synergy

in Predictive Toxicology

Simone Lederer
Tjeerd M. H. Dijkstra
Tom Heskes

Frontiers in Pharmacology

doi 10.3389/fphar.2019.01384

18,266 views
41 citations

Original Research

Published on 14 Nov 2019

Understanding the Bacterial Response to Mycotoxins: The Transcriptomic Analysis of Deoxynivalenol-Induced Changes in Devosia mutans 17-2-E-8

in Predictive Toxicology

Yousef I. Hassan
Jian Wei He
Dion Lepp
Ting Zhou

Frontiers in Pharmacology

doi 10.3389/fphar.2019.01098

3,639 views
10 citations

Case Report

Published on 08 Nov 2019

Hemolytic Anemia and Reactive Thrombocytosis Associated With Cefoperazone/Sulbactam

in Predictive Toxicology

Ling Zhou
Jianan Bao
Jingjing Ma

Frontiers in Pharmacology

doi 10.3389/fphar.2019.01342

8,238 views
8 citations

Review

Published on 06 Nov 2019

Phthalate-Induced Fetal Leydig Cell Dysfunction Mediates Male Reproductive Tract Anomalies

in Predictive Toxicology

Yiyan Wang
Chaobo Ni
Xiaoheng Li
Zhenkun Lin
Qiqi Zhu
Linxi Li
Ren-Shan Ge

Frontiers in Pharmacology

doi 10.3389/fphar.2019.01309

6,004 views
41 citations

Methods

Published on 06 Nov 2019

Unpredictable Nanoparticle Retention in Commonly Used Plastic Syringes Introduces Dosage Uncertainties That May Compromise the Accuracy of Nanomedicine and Nanotoxicology Studies

in Predictive Toxicology

Uwe Holzwarth
Unai Cossío
Jordi Llop
Wolfgang G. Kreyling

Frontiers in Pharmacology

doi 10.3389/fphar.2019.01293

4,230 views
10 citations