Perspective

Published on 11 Feb 2015

Dynamics of receptor-operated Ca2+ currents through TRPC channels controlled via the PI(4,5)P2-PLC signaling pathway

in Pharmacology of Ion Channels and Channelopathies

Masayuki X. Mori
Kyohei Itsuki
Hideharu Hase
Seishiro Sawamura
Tatsuki Kurokawa
Yasuo Mori
Ryuji Inoue

Frontiers in Pharmacology

doi 10.3389/fphar.2015.00022

7,760 views
23 citations

Review

Published on 10 Feb 2015

Voltage sensitive phosphatases: emerging kinship to protein tyrosine phosphatases from structure-function research

in Pharmacology of Ion Channels and Channelopathies

Kirstin Hobiger
Thomas Friedrich

Frontiers in Pharmacology

doi 10.3389/fphar.2015.00020

7,383 views
10 citations

Methods

Published on 02 Sep 2014

Early identification of hERG liability in drug discovery programs by automated patch clamp

in Pharmacology of Ion Channels and Channelopathies

Timm Danker
Clemens Möller

Frontiers in Pharmacology

doi 10.3389/fphar.2014.00203

27,478 views
89 citations

Editorial

Published on 03 Jul 2014

CaMKII comes of age in cardiac health and disease

in Pharmacology of Ion Channels and Channelopathies

Eleonora Grandi
Andrew G. Edwards
Anthony W. Herren
Donald M. Bers

Frontiers in Pharmacology

doi 10.3389/fphar.2014.00154

4,346 views
8 citations

Review

Published on 17 Jun 2014

Ca2+ current facilitation is CaMKII-dependent and has arrhythmogenic consequences

in Pharmacology of Ion Channels and Channelopathies

Donald M. Bers
Stefano Morotti

Frontiers in Pharmacology

doi 10.3389/fphar.2014.00144

9,942 views
52 citations

Review

Published on 16 May 2014

Toward a hierarchy of mechanisms in CaMKII-mediated arrhythmia

in Pharmacology of Ion Channels and Channelopathies

Kevin P. Vincent
Andrew D. McCulloch
Andrew G. Edwards

Frontiers in Pharmacology

doi 10.3389/fphar.2014.00110

7,498 views
16 citations

Review

Published on 08 May 2014

CaMKII regulation of cardiac ryanodine receptors and inositol triphosphate receptors

in Pharmacology of Ion Channels and Channelopathies

Emmanuel Camors
Héctor H. Valdivia

Frontiers in Pharmacology

doi 10.3389/fphar.2014.00101

11,274 views
58 citations

Review

Published on 06 May 2014

CaMKII-dependent responses to ischemia and reperfusion challenges in the heart

in Pharmacology of Ion Channels and Channelopathies

James R. Bell
Martin Vila-Petroff
Lea M. D. Delbridge

Frontiers in Pharmacology

doi 10.3389/fphar.2014.00096

7,673 views
37 citations

Review

Published on 01 May 2014

CaMKII and stress mix it up in mitochondria

in Pharmacology of Ion Channels and Channelopathies

Mei-ling A. Joiner
Olha M. Koval

Frontiers in Pharmacology

doi 10.3389/fphar.2014.00067

7,831 views
17 citations

Review

Published on 03 Apr 2014

Biophysics, pathophysiology, and pharmacology of ion channel gating pores

in Pharmacology of Ion Channels and Channelopathies

Adrien Moreau
Pascal Gosselin-Badaroudine
Mohamed Chahine

Frontiers in Pharmacology

doi 10.3389/fphar.2014.00053

16,130 views
78 citations

Review

Published on 03 Apr 2014

Modeling CaMKII-mediated regulation of L-type Ca2+ channels and ryanodine receptors in the heart

in Pharmacology of Ion Channels and Channelopathies

Joseph L Greenstein
Panagiota T Foteinou
Yasmin L Hashambhoy-Ramsay
Raimond L Winslow

Frontiers in Pharmacology

doi 10.3389/fphar.2014.00060

5,396 views
12 citations

Review

Published on 02 Apr 2014

Mechanisms of CaMKII Activation in the Heart

in Pharmacology of Ion Channels and Channelopathies

Jeffrey R Erickson

Frontiers in Pharmacology

doi 10.3389/fphar.2014.00059

20,576 views
115 citations

Mini Review

Published on 01 Apr 2014

Numerical Modeling Calcium and CaMKII Effects in the SA Node

in Pharmacology of Ion Channels and Channelopathies

Yael Yaniv
VICTOR A MALTSEV

Frontiers in Pharmacology

doi 10.3389/fphar.2014.00058

5,453 views
12 citations

Review

Published on 18 Mar 2014

CaMKII in sinoatrial node physiology and dysfunction

in Pharmacology of Ion Channels and Channelopathies

Yuejin Wu
Mark E Anderson

Frontiers in Pharmacology

doi 10.3389/fphar.2014.00048

9,471 views
45 citations

Review

Published on 12 Mar 2014

Integrated mechanisms of CaMKII-dependent ventricular remodeling

in Pharmacology of Ion Channels and Channelopathies

Michael M Kreusser
Johannes Backs

Frontiers in Pharmacology

doi 10.3389/fphar.2014.00036

14,218 views
81 citations

Original Research

Published on 11 Mar 2014

Identification of both GABAA receptors and voltage-activated Na+ channels as molecular targets of anticonvulsant α-asarone

in Pharmacology of Ion Channels and Channelopathies

Ze-Jun Wang
Simmon Rock Levinson
Liqin Sun
Thomas Heinbockel

Frontiers in Pharmacology

doi 10.3389/fphar.2014.00040

7,204 views
35 citations

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Articles

Dynamics of receptor-operated Ca2+ currents through TRPC channels controlled via the PI(4,5)P2-PLC signaling pathway

Voltage sensitive phosphatases: emerging kinship to protein tyrosine phosphatases from structure-function research

Early identification of hERG liability in drug discovery programs by automated patch clamp

CaMKII comes of age in cardiac health and disease

Ca2+ current facilitation is CaMKII-dependent and has arrhythmogenic consequences

Toward a hierarchy of mechanisms in CaMKII-mediated arrhythmia

CaMKII regulation of cardiac ryanodine receptors and inositol triphosphate receptors

CaMKII-dependent responses to ischemia and reperfusion challenges in the heart

CaMKII and stress mix it up in mitochondria

Biophysics, pathophysiology, and pharmacology of ion channel gating pores

Modeling CaMKII-mediated regulation of L-type Ca2+ channels and ryanodine receptors in the heart

Mechanisms of CaMKII Activation in the Heart

Numerical Modeling Calcium and CaMKII Effects in the SA Node

CaMKII in sinoatrial node physiology and dysfunction

Integrated mechanisms of CaMKII-dependent ventricular remodeling

Identification of both GABAA receptors and voltage-activated Na+ channels as molecular targets of anticonvulsant α-asarone