Mini Review

Published on 23 May 2024

Insights into the voltage-gated sodium channel, NaV1.8, and its role in visceral pain perception

in Pharmacology of Ion Channels and Channelopathies

J. Westley Heinle
Shannon Dalessio
Piotr Janicki
Ann Ouyang
Kent E. Vrana
Victor Ruiz-Velasco
Matthew D. Coates

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1398409

2,434 views

Editorial

Published on 13 May 2024

Editorial: Advancing therapeutic strategies: exploring ABC transporters and chemicals affecting their expression and function for disease treatment

in Pharmacology of Ion Channels and Channelopathies

Guido Veit
Michinori Matsuo
Tsukasa Okiyoneda

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1423979

589 views

Review

Published on 09 May 2024

Exploring the therapeutic opportunities of potassium channels for the treatment of rheumatoid arthritis

in Pharmacology of Ion Channels and Channelopathies

Nikhil Eknath More
Rahul Mandlik
Sandip Zine
Vaibhavkumar S. Gawali
Angel Pavalu Godad

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1286069

1,945 views

Original Research

Published on 02 May 2024

The road to evolution of ProTx2: how to be a subtype-specific inhibition of human Nav1.7

in Pharmacology of Ion Channels and Channelopathies

Fan Zhao
Yuanyuan Liu
Yiyu Liu
Qi Ye
Hongtao Yang
Mingze Gui
Yongbo Song

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1374183

844 views

Review

Published on 25 Apr 2024

Functional effects of drugs and toxins interacting with NaV1.4

in Pharmacology of Ion Channels and Channelopathies

Xinyi Zou
Zixuan Zhang
Hui Lu
Wei Zhao
Lanying Pan
Yuan Chen

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1378315

5,948 views

Original Research

Published on 25 Apr 2024

Readthrough-induced misincorporated amino acid ratios guide mutant-specific therapeutic approaches for two CFTR nonsense mutations

in Pharmacology of Ion Channels and Channelopathies

Aiswarya Premchandar
Ruiji Ming
Abed Baiad
Dillon F. Da Fonte
Haijin Xu
Denis Faubert
Guido Veit
Gergely L. Lukacs

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1389586

2,119 views
2 citations

Original Research

Published on 11 Apr 2024

Ligand-based virtual-screening identified a novel CFTR ligand which improves the defective cell surface expression of misfolded ABC transporters

in Pharmacology of Ion Channels and Channelopathies

Shogo Taniguchi
Francois Berenger
Yukako Doi
Ayana Mimura
Yoshihiro Yamanishi
Tsukasa Okiyoneda

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1370676

1,325 views

Original Research

Published on 10 Apr 2024

Use of tetraethylammonium (TEA) and Tris loading for blocking TRPM7 channels in intact cells

in Pharmacology of Ion Channels and Channelopathies

Katherine G. Holderby
J. Ashot Kozak

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1341799

2,176 views

Editorial

Published on 10 Apr 2024

Editorial: Structural and functional venomics as a powerful approach for drug discovery and development

in Pharmacology of Ion Channels and Channelopathies

Mohamed A. Abdel-Rahman
Zhijian Cao
Tarek Mohamed Abd El-Aziz
Peter N. Strong
Jean-Marc Sabatier

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1405681

892 views

Review

Published on 09 Apr 2024

Ion transporter cascade, reactive astrogliosis and cerebrovascular diseases

in Pharmacology of Ion Channels and Channelopathies

Md Shamim Rahman
Rabia Islam
Mohammad Iqbal H. Bhuiyan

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1374408

1,754 views
2 citations

Original Research

Published on 04 Apr 2024

Intracellular acidity impedes KCa3.1 activation by Riluzole and SKA-31

in Pharmacology of Ion Channels and Channelopathies

Marco Cozzolino
Gyorgy Panyi

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1380655

1,003 views

Review

Published on 22 Mar 2024

Large conductance voltage-and calcium-activated K+ (BK) channel in health and disease

in Pharmacology of Ion Channels and Channelopathies

Felipe Echeverría
Naileth Gonzalez-Sanabria
Rosangelina Alvarado-Sanchez
Miguel Fernández
Karen Castillo
Ramon Latorre

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1373507

2,301 views
2 citations

Original Research

Published on 07 Mar 2024

CBA (4-chloro-2-(2-chlorophenoxy)acetamido) benzoic acid) inhibits TMEM206 mediated currents and TMEM206 does not contribute to acid-induced cell death in colorectal cancer cells

in Pharmacology of Ion Channels and Channelopathies

Sven Kappel
Korollus Melek
Daniela Ross-Kaschitza
Barbara Hauert
Christian E. Gerber
Martin Lochner
Christine Peinelt

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1369513

1,515 views

Original Research

Published on 19 Feb 2024

Comparing ATPase activity of ATP-binding cassette subfamily C member 4, lamprey CFTR, and human CFTR using an antimony-phosphomolybdate assay

in Pharmacology of Ion Channels and Channelopathies

Guiying Cui
Kerry M. Strickland
Analia J. Vazquez Cegla
Nael A. McCarty

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1363456

1,342 views

Review

Published on 15 Feb 2024

Application of calcium overload-based ion interference therapy in tumor treatment: strategies, outcomes, and prospects

in Pharmacology of Ion Channels and Channelopathies

Shuangjiang Li
Ruicheng Fan
Yuekai Wang
Kunqian He
Jinhe Xu
Hongli Li

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1352377

2,063 views
1 citation

Review

Published on 24 Jan 2024

A journey from molecule to physiology and in silico tools for drug discovery targeting the transient receptor potential vanilloid type 1 (TRPV1) channel

in Pharmacology of Ion Channels and Channelopathies

Cesar A. Amaya-Rodriguez
Karina Carvajal-Zamorano
Daniel Bustos
Melissa Alegría-Arcos
Karen Castillo

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1251061

4,489 views
3 citations

Navigation group

Articles

Insights into the voltage-gated sodium channel, NaV1.8, and its role in visceral pain perception

Editorial: Advancing therapeutic strategies: exploring ABC transporters and chemicals affecting their expression and function for disease treatment

Exploring the therapeutic opportunities of potassium channels for the treatment of rheumatoid arthritis

The road to evolution of ProTx2: how to be a subtype-specific inhibition of human Nav1.7

Functional effects of drugs and toxins interacting with NaV1.4

Readthrough-induced misincorporated amino acid ratios guide mutant-specific therapeutic approaches for two CFTR nonsense mutations

Ligand-based virtual-screening identified a novel CFTR ligand which improves the defective cell surface expression of misfolded ABC transporters

Use of tetraethylammonium (TEA) and Tris loading for blocking TRPM7 channels in intact cells

Editorial: Structural and functional venomics as a powerful approach for drug discovery and development

Ion transporter cascade, reactive astrogliosis and cerebrovascular diseases

Intracellular acidity impedes KCa3.1 activation by Riluzole and SKA-31

Large conductance voltage-and calcium-activated K+ (BK) channel in health and disease

CBA (4-chloro-2-(2-chlorophenoxy)acetamido) benzoic acid) inhibits TMEM206 mediated currents and TMEM206 does not contribute to acid-induced cell death in colorectal cancer cells

Comparing ATPase activity of ATP-binding cassette subfamily C member 4, lamprey CFTR, and human CFTR using an antimony-phosphomolybdate assay

Application of calcium overload-based ion interference therapy in tumor treatment: strategies, outcomes, and prospects

A journey from molecule to physiology and in silico tools for drug discovery targeting the transient receptor potential vanilloid type 1 (TRPV1) channel