Original Research

Published on 16 Dec 2021

Mechanisms Underlying Gastrodin Alleviating Vincristine-Induced Peripheral Neuropathic Pain

in Pharmacology of Ion Channels and Channelopathies

Xiangyu Wang
Boxuan Zhang
Xuedong Li
Xingang Liu
Songsong Wang
Yuan Xie
Jialing Pi
Zhiyuan Yang
Jincan Li
Qingzhong Jia

Frontiers in Pharmacology

doi 10.3389/fphar.2021.744663

3,810 views
12 citations

Original Research

Published on 08 Dec 2021

Inhibition of the Nav1.7 Channel in the Trigeminal Ganglion Relieves Pulpitis Inflammatory Pain

in Pharmacology of Ion Channels and Channelopathies

Minjee Kwon
Il Young Jung
Myeounghoon Cha
Bae Hwan Lee

Frontiers in Pharmacology

doi 10.3389/fphar.2021.759730

3,287 views
6 citations

Original Research

Published on 08 Dec 2021

Unique Pharmacological Properties of α-Conotoxin OmIA at α7 nAChRs

in Pharmacology of Ion Channels and Channelopathies

Thao N.T. Ho
Nikita Abraham
Richard J. Lewis

Frontiers in Pharmacology

doi 10.3389/fphar.2021.803397

1,976 views
5 citations

Original Research

Published on 08 Dec 2021

The Na+/Ca2+ Exchanger 3 Is Functionally Coupled With the NaV1.6 Voltage-Gated Channel and Promotes an Endoplasmic Reticulum Ca2+ Refilling in a Transgenic Model of Alzheimer’s Disease

in Pharmacology of Ion Channels and Channelopathies

Ilaria Piccialli
Roselia Ciccone
Agnese Secondo
Francesca Boscia
Valentina Tedeschi
Valeria de Rosa
Pasquale Cepparulo
Lucio Annunziato
Anna Pannaccione

Frontiers in Pharmacology

doi 10.3389/fphar.2021.775271

3,902 views
9 citations

Original Research

Published on 07 Dec 2021

Screening for Activity Against AMPA Receptors Among Anticonvulsants—Focus on Phenytoin

in Pharmacology of Ion Channels and Channelopathies

M. Y. Dron
A. S. Zhigulin
D. B. Tikhonov
O. I. Barygin

Frontiers in Pharmacology

doi 10.3389/fphar.2021.775040

3,805 views
3 citations

Original Research

Published on 06 Dec 2021

A Novel Spider Toxin Inhibits Fast Inactivation of the Nav1.9 Channel by Binding to Domain III and Domain IV Voltage Sensors

in Pharmacology of Ion Channels and Channelopathies

Shuijiao Peng
Minzhi Chen
Zhen Xiao
Xin Xiao
Sen Luo
Songping Liang
Xi Zhou
Zhonghua Liu

Frontiers in Pharmacology

doi 10.3389/fphar.2021.778534

3,254 views
3 citations

Original Research

Published on 02 Dec 2021

The L1624Q Variant in SCN1A Causes Familial Epilepsy Through a Mixed Gain and Loss of Channel Function

in Pharmacology of Ion Channels and Channelopathies

Laura B. Jones
Colin H. Peters
Richard E. Rosch
Maxine Owers
Elaine Hughes
Deb K. Pal
Peter C. Ruben

Frontiers in Pharmacology

doi 10.3389/fphar.2021.788192

3,338 views
4 citations

Original Research

Published on 01 Dec 2021

The Human SCN10AG1662S Point Mutation Established in Mice Impacts on Mechanical, Heat, and Cool Sensitivity

in Pharmacology of Ion Channels and Channelopathies

Celeste Chidiac
Yaping Xue
Maria del Mar Muniz Moreno
Ameer Abu Bakr Rasheed
Romain Lorentz
Marie-Christine Birling
Claire Gaveriaux-Ruff
Yann Herault

Frontiers in Pharmacology

doi 10.3389/fphar.2021.780132

3,609 views
5 citations

Original Research

Published on 01 Dec 2021

Toxic Peptide From Palythoa caribaeorum Acting on the TRPV1 Channel Prevents Pentylenetetrazol-Induced Epilepsy in Zebrafish Larvae

in Pharmacology of Ion Channels and Channelopathies

Xiufen Wang
Qiwen Liao
Hanbin Chen
Guiyi Gong
Shirley Weng In Siu
Qian Chen
Hiotong Kam
Carolina Oi Lam Ung
Kwok-Kuen Cheung
Gandhi Rádis-Baptista

Frontiers in Pharmacology

doi 10.3389/fphar.2021.763089

4,144 views
3 citations

Original Research

Published on 25 Nov 2021

Synergistic Effect of Proteinase Activity by Purification and Identification of Toxic Protease From Nemopilema nomurai

in Pharmacology of Ion Channels and Channelopathies

Chunlin Yu
Rongfeng Li
Xiujing Yin
Huahua Yu
Pengcheng Li

Frontiers in Pharmacology

doi 10.3389/fphar.2021.791847

2,279 views
5 citations

Original Research

Published on 19 Nov 2021

Loss-of-Function Piezo1 Mutations Display Altered Stability Driven by Ubiquitination and Proteasomal Degradation

in Pharmacology of Ion Channels and Channelopathies

Zijing Zhou
Jinyuan Vero Li
Boris Martinac
Charles D. Cox

Frontiers in Pharmacology

doi 10.3389/fphar.2021.766416

4,267 views
8 citations

Original Research

Published on 19 Nov 2021

Molecular Pathology of Sodium Channel Beta-Subunit Variants

in Pharmacology of Ion Channels and Channelopathies

Paweorn Angsutararux
Wandi Zhu
Taylor L. Voelker
Jonathan R. Silva

Frontiers in Pharmacology

doi 10.3389/fphar.2021.761275

3,274 views
19 citations

Original Research

Published on 17 Nov 2021

Pathogenic in-Frame Variants in SCN8A: Expanding the Genetic Landscape of SCN8A-Associated Disease

in Pharmacology of Ion Channels and Channelopathies

Jennifer C. Wong
Kameryn M. Butler
Lindsey Shapiro
Jacquelyn T. Thelin
Kari A. Mattison
Kathryn B. Garber
Paula C. Goldenberg
Shobana Kubendran
G. Bradley Schaefer
Andrew Escayg

Frontiers in Pharmacology

doi 10.3389/fphar.2021.748415

2,962 views
1 citation

Correction

Published on 17 Nov 2021

Corrigendum: Convergence of Multiple Stimuli to a Single Gate in TREK1 and TRAAK Potassium Channels

in Pharmacology of Ion Channels and Channelopathies

Frank S. Choveau
Ismail Ben Soussia
Delphine Bichet
Franck C. Chatelain
Sylvain Feliciangeli
Florian Lesage

Frontiers in Pharmacology

doi 10.3389/fphar.2021.795920

916 views
1 citation

Review

Published on 10 Nov 2021

Ion Channel Dysfunction and Neuroinflammation in Migraine and Depression

in Pharmacology of Ion Channels and Channelopathies

Emine Eren-Koçak
Turgay Dalkara

Frontiers in Pharmacology

doi 10.3389/fphar.2021.777607

8,093 views
20 citations

Original Research

Published on 04 Nov 2021

Intersegment Contacts of Potentially Damaging Variants of Cardiac Sodium Channel

in Pharmacology of Ion Channels and Channelopathies

Vyacheslav S. Korkosh
Anastasia K. Zaytseva
Anna A. Kostareva
Boris S. Zhorov

Frontiers in Pharmacology

doi 10.3389/fphar.2021.756415

2,878 views
3 citations

Navigation group

Articles

Mechanisms Underlying Gastrodin Alleviating Vincristine-Induced Peripheral Neuropathic Pain

Inhibition of the Nav1.7 Channel in the Trigeminal Ganglion Relieves Pulpitis Inflammatory Pain

Unique Pharmacological Properties of α-Conotoxin OmIA at α7 nAChRs

The Na+/Ca2+ Exchanger 3 Is Functionally Coupled With the NaV1.6 Voltage-Gated Channel and Promotes an Endoplasmic Reticulum Ca2+ Refilling in a Transgenic Model of Alzheimer’s Disease

Screening for Activity Against AMPA Receptors Among Anticonvulsants—Focus on Phenytoin

A Novel Spider Toxin Inhibits Fast Inactivation of the Nav1.9 Channel by Binding to Domain III and Domain IV Voltage Sensors

The L1624Q Variant in SCN1A Causes Familial Epilepsy Through a Mixed Gain and Loss of Channel Function

The Human SCN10AG1662S Point Mutation Established in Mice Impacts on Mechanical, Heat, and Cool Sensitivity

Toxic Peptide From Palythoa caribaeorum Acting on the TRPV1 Channel Prevents Pentylenetetrazol-Induced Epilepsy in Zebrafish Larvae

Synergistic Effect of Proteinase Activity by Purification and Identification of Toxic Protease From Nemopilema nomurai

Loss-of-Function Piezo1 Mutations Display Altered Stability Driven by Ubiquitination and Proteasomal Degradation

Molecular Pathology of Sodium Channel Beta-Subunit Variants

Pathogenic in-Frame Variants in SCN8A: Expanding the Genetic Landscape of SCN8A-Associated Disease

Corrigendum: Convergence of Multiple Stimuli to a Single Gate in TREK1 and TRAAK Potassium Channels

Ion Channel Dysfunction and Neuroinflammation in Migraine and Depression

Intersegment Contacts of Potentially Damaging Variants of Cardiac Sodium Channel