Frontiers in Pharmacology | Pharmacology of Ion Channels and Channelopathies

Original Research

Published on 06 Jan 2025

pH-induced conformational changes in the selectivity filter of a potassium channel lead to alterations in its selectivity and permeation properties

in Pharmacology of Ion Channels and Channelopathies

Carlos Coll-Díez
Ana Marcela Giudici
Alberto Potenza
José Manuel González-Ros
José Antonio Poveda

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1499383

209 views

Review

Accepted on 31 Dec 2024

The enigmatic SLC26A6 multifunctional anion transporter: Recent advances in structure-function relationship, pathophysiological significance and novel pharmacological a

in Pharmacology of Ion Channels and Channelopathies

Ursula E. Seidler

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1536864

Original Research

Published on 18 Nov 2024

Pharmacological rescue of the G85E CFTR variant by preclinical and approved modulators

in Pharmacology of Ion Channels and Channelopathies

Valeria Tomati
Valeria Capurro
Emanuela Pesce
Cristina Pastorino
Elvira Sondo
Mariateresa Lena
Anna Borrelli
Federico Cresta
Stefano Pantano
Francesca Collini

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1494327

727 views

Original Research

Published on 14 Oct 2024

GABA Type A receptors expressed in triple negative breast cancer cells mediate chloride ion flux

in Pharmacology of Ion Channels and Channelopathies

J Bundy
Y Ahmed
S Weller
J Nguyen
J Shaw
I Mercier
A Suryanarayanan

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1449256

1,034 views

Original Research

Published on 09 Oct 2024

The diversity of AMPA receptor inhibition mechanisms among amidine-containing compounds

in Pharmacology of Ion Channels and Channelopathies

Arseniy S. Zhigulin
Mikhail Y. Dron
Oleg I. Barygin
Denis B. Tikhonov

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1467266

794 views

Review

Published on 19 Sep 2024

The role of TRPV1 in chronic prostatitis: a review

in Pharmacology of Ion Channels and Channelopathies

Zhipeng Jiang
Wen Luo
Zongmin Long
Jie Chen

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1459683

1,255 views

Original Research

Published on 26 Aug 2024

Endocannabinoid regulation of inward rectifier potassium (Kir) channels

in Pharmacology of Ion Channels and Channelopathies

Sultan Mayar
Mariia Borbuliak
Andreas Zoumpoulakis
Tahar Bouceba
Madeleine M. Labonté
Ameneh Ahrari
Niveny Sinniah
Mina Memarpoor-Yazdi
Catherine Vénien-Bryan
D. Peter Tieleman

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1439767

1,295 views
1 citation

Editorial

Published on 20 Aug 2024

Editorial: Reviews in pharmacology of ion channels and channelopathies

in Pharmacology of Ion Channels and Channelopathies

Jinwei Zhang
Jean-Marc Sabatier
Mohamed Chahine
Domenico Tricarico

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1449967

738 views

Review

Published on 30 Jul 2024

Unlocking the therapeutic potential of P2X7 receptor: a comprehensive review of its role in neurodegenerative disorders

in Pharmacology of Ion Channels and Channelopathies

Xiaoming Liu
Yiwen Li
Liting Huang
Yingyan Kuang
Xiaoxiong Wu
Xiangqiong Ma
Beibei Zhao
Jiao Lan

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1450704

2,722 views
2 citations

Original Research

Published on 25 Jul 2024

Unlocking cellular traffic jams: olive oil-mediated rescue of CNG mutant channels

in Pharmacology of Ion Channels and Channelopathies

Angeles Avalos-Hernandez
Karina Juarez-Navarro
Estela Ruiz-Baca
Ivan Meneses-Morales
Edith Espino-Saldaña
Ataulfo Martinez-Torres
Angelica Lopez-Rodriguez

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1408156

1,994 views

Review

Published on 09 Jul 2024

Therapeutic targeting of voltage-gated sodium channel NaV1.7 for cancer metastasis

in Pharmacology of Ion Channels and Channelopathies

Piyasuda Pukkanasut
Renata Jaskula-Sztul
Juan Carlos Gomora
Sadanandan E. Velu

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1416705

2,221 views

Editorial

Published on 02 Jul 2024

Editorial: Intracellular ion channels in health and disease

in Pharmacology of Ion Channels and Channelopathies

Giovanni Zifarelli
Michael Pusch
Tobias Stauber

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1430150

632 views

Mini Review

Published on 01 Jul 2024

The role of potassium ion channels in chronic sinusitis

in Pharmacology of Ion Channels and Channelopathies

Changhui Ding
Senxi Gai
Zhiyong Ma
Lizhuo Yang
Zhijie Fu

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1431330

1,964 views

Original Research

Published on 26 Jun 2024

Eugenol and lidocaine inhibit voltage-gated Na+ channels from dorsal root ganglion neurons with different mechanisms

in Pharmacology of Ion Channels and Channelopathies

Luiz Moreira-Junior
Jose Henrique Leal-Cardoso
Antonio Carlos Cassola
Joao Luis Carvalho-de-Souza

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1354737

1,580 views

Original Research

Published on 26 Jun 2024

Activation of Piezo1 or TRPV2 channels inhibits human ureteral contractions via NO release from the mucosa

in Pharmacology of Ion Channels and Channelopathies

Jianing Liu
Cong Wang
Wenyu Wang
Ning Ding
Jiaxin Liu
Hanwen Liu
Jiliang Wen
Wendong Sun
Shulu Zu
Xiulin Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1410565

2,597 views

Editorial

Published on 18 Jun 2024

Editorial: Ion channels and transporters as drug targets in immune disorders

in Pharmacology of Ion Channels and Channelopathies

Vaibhavkumar S. Gawali
Yogesh B. Narkhede
Sachin Kumar

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1439156

653 views

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Articles

pH-induced conformational changes in the selectivity filter of a potassium channel lead to alterations in its selectivity and permeation properties

The enigmatic SLC26A6 multifunctional anion transporter: Recent advances in structure-function relationship, pathophysiological significance and novel pharmacological a

Pharmacological rescue of the G85E CFTR variant by preclinical and approved modulators

GABA Type A receptors expressed in triple negative breast cancer cells mediate chloride ion flux

The diversity of AMPA receptor inhibition mechanisms among amidine-containing compounds

The role of TRPV1 in chronic prostatitis: a review

Endocannabinoid regulation of inward rectifier potassium (Kir) channels

Editorial: Reviews in pharmacology of ion channels and channelopathies

Unlocking the therapeutic potential of P2X7 receptor: a comprehensive review of its role in neurodegenerative disorders

Unlocking cellular traffic jams: olive oil-mediated rescue of CNG mutant channels

Therapeutic targeting of voltage-gated sodium channel NaV1.7 for cancer metastasis

Editorial: Intracellular ion channels in health and disease

The role of potassium ion channels in chronic sinusitis

Eugenol and lidocaine inhibit voltage-gated Na+ channels from dorsal root ganglion neurons with different mechanisms

Activation of Piezo1 or TRPV2 channels inhibits human ureteral contractions via NO release from the mucosa

Editorial: Ion channels and transporters as drug targets in immune disorders