Original Research

Published on 05 Dec 2023

Evaluation of variable new antigen receptors (vNARs) as a novel cathepsin S (CTSS) targeting strategy

in Pharmacology of Anti-Cancer Drugs

P. Smyth
L. Ferguson
J. F. Burrows
R. E. Burden
S. R. Tracey
Ú. M. Herron
M. Kovaleva
R. Williams
A. J. Porter
D. B. Longley

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1296567

1,714 views
1 citation

Original Research

Published on 30 Nov 2023

Design, synthesis, and evaluation of 4-(3-(3,5-dimethylisoxazol-4-yl)benzyl)phthalazin-1(2H)-one derivatives: potent BRD4 inhibitors with anti-breast cancer activity

in Pharmacology of Anti-Cancer Drugs

Yingpeng Li
Xinhong Chu
Yu Yin
Hongkun Li
Hui Fu
Xinchi Feng
Yanru Deng
Jun Ge

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1289003

1,624 views
3 citations

Original Research

Published on 27 Nov 2023

Association between antihypertensive drugs and oral cancer: a drug target Mendelian randomization study

in Pharmacology of Anti-Cancer Drugs

Junfeng Guo
Rongxing Liu
Fangfang Sheng
Qiuxiang Wu
Rufu Xu
Haitao He
Gang Zhang
Junjie Huang
Zhe Zhang
Rong Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1294297

3,945 views
4 citations

Original Research

Published on 23 Nov 2023

Multi-level characteristics recognition of cancer core therapeutic targets and drug screening for a broader patient population

in Pharmacology of Anti-Cancer Drugs

Yangguang Su
Ying Wang
Zhuo Qu
Jiaxin Liu
Xuekun Ren
Denan Zhang
Xiujie Chen

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1280099

1,310 views

Systematic Review

Published on 22 Nov 2023

Comparing efficacy of first-line treatment of metastatic castration resistant prostate cancer: a network meta-analysis of randomized controlled trials

in Pharmacology of Anti-Cancer Drugs

Yang Liu
Xianzhong Deng
Zhi Wen
Jing Huang
Chongjian Wang
Caixia Chen
Erhao Bao
Jiahao Wang
Xuesong Yang

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1290990

2,248 views
1 citation

Review

Published on 21 Nov 2023

Genome-wide CRISPR/Cas9 screening for drug resistance in tumors

in Pharmacology of Anti-Cancer Drugs

Zhongyan Zhang
Hailiang Wang
Qian Yan
Jinwei Cui
Yubin Chen
Shiye Ruan
Jiayu Yang
Zelong Wu
Mingqian Han
Shanzhou Huang

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1284610

5,653 views
3 citations

Original Research

Published on 20 Nov 2023

Integrating bulk and single-cell RNA sequencing data reveals epithelial-mesenchymal transition molecular subtype and signature to predict prognosis, immunotherapy efficacy, and drug candidates in low-grade gliomas

in Pharmacology of Anti-Cancer Drugs

Chengcheng Wang
Zheng He

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1276466

2,291 views
4 citations

Original Research

Published on 20 Nov 2023

Development and validation of a disulfidptosis-related scoring system to predict clinical outcome and immunotherapy response in acute myeloid leukemia by integrated analysis of single-cell and bulk RNA-sequencing

in Pharmacology of Anti-Cancer Drugs

Fangmin Zhong
Junyao Jiang
Fang-Yi Yao
Jing Liu
Xu Shuai
Xin-Lu Wang
Bo Huang
Xiaozhong Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1272701

2,346 views
1 citation

Review

Published on 17 Nov 2023

A review on the mechanisms underlying the antitumor effects of natural products by targeting the endoplasmic reticulum stress apoptosis pathway

in Pharmacology of Anti-Cancer Drugs

Jie-Xiang Zhang
Wei-Chen Yuan
Cheng-Gang Li
Hai-Yan Zhang
Shu-Yan Han
Xiao-Hong Li

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1293130

2,629 views
3 citations

Original Research

Published on 17 Nov 2023

Insights on epithelial cells at the single-cell level in hepatocellular carcinoma prognosis and response to chemotherapy

in Pharmacology of Anti-Cancer Drugs

Wenqian Qi
Qian Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1292831

1,955 views
4 citations

Case Report

Published on 16 Nov 2023

Case report: Olverembatinib monotherapy: the chemotherapy-free regimen for an elderly patient with relapsed Ph-positive acute lymphoblastic leukemia

in Pharmacology of Anti-Cancer Drugs

Jianghua Ding
Wen Li

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1320641

1,414 views

Original Research

Published on 15 Nov 2023

Cellular crosstalk of macrophages and therapeutic implications in non-small cell lung cancer revealed by integrative inference of single-cell transcriptomics

in Pharmacology of Anti-Cancer Drugs

Lei Wu
Wenying Xia
Yiting Hua
Kun Fan
Yanfei Lu
Min Wang
Yuexinzi Jin
Wei Zhang
Shiyang Pan

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1295442

2,693 views
3 citations

Original Research

Published on 15 Nov 2023

The association between aspirin use and immune-related adverse events in specific cancer patients receiving ICIs therapy: analysis of the FAERS database

in Pharmacology of Anti-Cancer Drugs

Huaju Yang
Zheran Liu
Ruidan Li
Rendong Huang
Xingchen Peng

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1259628

3,546 views
3 citations

Original Research

Published on 15 Nov 2023

Construction of EMT related prognostic signature for kidney renal clear cell carcinoma, through integrating bulk and single-cell gene expression profiles

in Pharmacology of Anti-Cancer Drugs

Qi Huang
Feiyu Li
Li Liu
Rui Xu
Tao Yang
Xiaoyun Ma
Hongmei Zhang
Yan Zhou
Yongxiang Shao
Qiaofeng Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1302142

1,964 views
1 citation

Original Research

Published on 15 Nov 2023

Integrated investigation and experimental validation of PPARG as an oncogenic driver: implications for prognostic assessment and therapeutic targeting in hepatocellular carcinoma

in Pharmacology of Anti-Cancer Drugs

Yunsheng Ran
Chujiao Hu
Junzhao Wan
Qian Kang
Ruixian Zhou
Ping Liu
Dan Ma
Jianta Wang
Lei Tang

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1298341

1,673 views
1 citation

Case Report

Published on 14 Nov 2023

Stevens–Johnson syndrome induced by toripalimab in a previously EGFR-TKI-treated advanced lung adenocarcinoma patient harboring EGFR mutations 19 del/T790M/C797S in trans and cis: a case report

in Pharmacology of Anti-Cancer Drugs

Yang Chen
Hanhan Hong
Shujun Bao
Hao Tang

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1131703

2,185 views
1 citation

Navigation group

Articles

Evaluation of variable new antigen receptors (vNARs) as a novel cathepsin S (CTSS) targeting strategy

Design, synthesis, and evaluation of 4-(3-(3,5-dimethylisoxazol-4-yl)benzyl)phthalazin-1(2H)-one derivatives: potent BRD4 inhibitors with anti-breast cancer activity

Association between antihypertensive drugs and oral cancer: a drug target Mendelian randomization study

Multi-level characteristics recognition of cancer core therapeutic targets and drug screening for a broader patient population

Comparing efficacy of first-line treatment of metastatic castration resistant prostate cancer: a network meta-analysis of randomized controlled trials

Genome-wide CRISPR/Cas9 screening for drug resistance in tumors

Integrating bulk and single-cell RNA sequencing data reveals epithelial-mesenchymal transition molecular subtype and signature to predict prognosis, immunotherapy efficacy, and drug candidates in low-grade gliomas

Development and validation of a disulfidptosis-related scoring system to predict clinical outcome and immunotherapy response in acute myeloid leukemia by integrated analysis of single-cell and bulk RNA-sequencing

A review on the mechanisms underlying the antitumor effects of natural products by targeting the endoplasmic reticulum stress apoptosis pathway

Insights on epithelial cells at the single-cell level in hepatocellular carcinoma prognosis and response to chemotherapy

Case report: Olverembatinib monotherapy: the chemotherapy-free regimen for an elderly patient with relapsed Ph-positive acute lymphoblastic leukemia

Cellular crosstalk of macrophages and therapeutic implications in non-small cell lung cancer revealed by integrative inference of single-cell transcriptomics

The association between aspirin use and immune-related adverse events in specific cancer patients receiving ICIs therapy: analysis of the FAERS database

Construction of EMT related prognostic signature for kidney renal clear cell carcinoma, through integrating bulk and single-cell gene expression profiles

Integrated investigation and experimental validation of PPARG as an oncogenic driver: implications for prognostic assessment and therapeutic targeting in hepatocellular carcinoma

Stevens–Johnson syndrome induced by toripalimab in a previously EGFR-TKI-treated advanced lung adenocarcinoma patient harboring EGFR mutations 19 del/T790M/C797S in trans and cis: a case report