Original Research

Published on 23 Dec 2016

A Novel Sensitive Method to Measure Catechol-O-Methyltransferase Activity Unravels the Presence of This Activity in Extracellular Vesicles Released by Rat Hepatocytes

in Pharmacogenetics and Pharmacogenomics

Enriqueta Casal
Laura Palomo
Diana Cabrera
Juan M. Falcon-Perez

Frontiers in Pharmacology

doi 10.3389/fphar.2016.00501

5,708 views
8 citations

Case Report

Published on 19 Dec 2016

Rivaroxaban-Induced Hemorrhage Associated with ABCB1 Genetic Defect

in Pharmacogenetics and Pharmacogenomics

Kuntheavy Ing Lorenzini
Youssef Daali
Pierre Fontana
Jules Desmeules
Caroline Samer

Frontiers in Pharmacology

doi 10.3389/fphar.2016.00494

7,497 views
54 citations

Original Research

Published on 02 Dec 2016

Pharmacogenomic Study Reveals New Variants of Drug Metabolizing Enzyme and Transporter Genes Associated with Steady-State Plasma Concentrations of Risperidone and 9-Hydroxyrisperidone in Thai Autism Spectrum Disorder Patients

in Pharmacogenetics and Pharmacogenomics

Sadeep Medhasi
Darawan Pinthong
Ekawat Pasomsub
Natchaya Vanwong
Nattawat Ngamsamut
Apichaya Puangpetch
Monpat Chamnanphon
Yaowaluck Hongkaew
Jirawat Pratoomwun
Penkhae Limsila

Frontiers in Pharmacology

doi 10.3389/fphar.2016.00475

5,043 views
17 citations

Review

Published on 01 Dec 2016

Cysteinyl Leukotrienes Pathway Genes, Atopic Asthma and Drug Response: From Population Isolates to Large Genome-Wide Association Studies

in Pharmacogenetics and Pharmacogenomics

Miles D. Thompson
Valerie Capra
Mark T. Clunes
G. E. Rovati
Jana Stankova
Mary C. Maj
David L. Duffy

Frontiers in Pharmacology

doi 10.3389/fphar.2016.00299

9,386 views
30 citations

Review

Published on 25 Nov 2016

Pregnane X Receptor (PXR)-Mediated Gene Repression and Cross-Talk of PXR with Other Nuclear Receptors via Coactivator Interactions

in Pharmacogenetics and Pharmacogenomics

Petr Pavek

Frontiers in Pharmacology

doi 10.3389/fphar.2016.00456

34,854 views
125 citations

Original Research

Published on 24 Nov 2016

Impact of CYP2C19 Variants on Clinical Efficacy of Clopidogrel and 1-Year Clinical Outcomes in Coronary Heart Patients Undergoing Percutaneous Coronary Intervention

in Pharmacogenetics and Pharmacogenomics

Hong Sun
Qiang Qu
Zhen-Fan Chen
Sheng-Lan Tan
Hai-Jun Zhou
Jian Qu
Hui Chen

Frontiers in Pharmacology

doi 10.3389/fphar.2016.00453

4,652 views
17 citations

Original Research

Published on 16 Nov 2016

Age-Dependent Hepatic UDP-Glucuronosyltransferase Gene Expression and Activity in Children

in Pharmacogenetics and Pharmacogenomics

Elizabeth Neumann
Huma Mehboob
Jacqueline Ramírez
Snezana Mirkov
Min Zhang
Wanqing Liu

Frontiers in Pharmacology

doi 10.3389/fphar.2016.00437

8,063 views
38 citations

Original Research

Published on 14 Nov 2016

Introduction of an N-Glycosylation Site into UDP-Glucuronosyltransferase 2B3 Alters Its Sensitivity to Cytochrome P450 3A1-Dependent Modulation

in Pharmacogenetics and Pharmacogenomics

Tatsuro Nakamura
Naho Yamaguchi
Yuu Miyauchi
Tomoki Takeda
Yasushi Yamazoe
Kiyoshi Nagata
Peter I. Mackenzie
Hideyuki Yamada
Yuji Ishii

Frontiers in Pharmacology

doi 10.3389/fphar.2016.00427

3,781 views
11 citations

Perspective

Published on 27 Oct 2016

Pharmacometabolomics Informs Viromics toward Precision Medicine

in Pharmacogenetics and Pharmacogenomics

Angeliki Balasopoulou
George P. Patrinos
Theodora Katsila

Frontiers in Pharmacology

doi 10.3389/fphar.2016.00411

3,794 views
15 citations

Review

Published on 24 Oct 2016

Structure and Protein–Protein Interactions of Human UDP-Glucuronosyltransferases

in Pharmacogenetics and Pharmacogenomics

Ryoichi Fujiwara
Tsuyoshi Yokoi
Miki Nakajima

Frontiers in Pharmacology

doi 10.3389/fphar.2016.00388

12,549 views
53 citations

Review

Published on 21 Oct 2016

Pharmacogenetics and Predictive Testing of Drug Hypersensitivity Reactions

in Pharmacogenetics and Pharmacogenomics

Ruwen Böhm
Ingolf Cascorbi

Frontiers in Pharmacology

doi 10.3389/fphar.2016.00396

12,446 views
31 citations

Original Research

Published on 29 Sep 2016

FCERI and Histamine Metabolism Gene Variability in Selective Responders to NSAIDS

in Pharmacogenetics and Pharmacogenomics

Gemma Amo
José A. Cornejo-García
Jesus M. García-Menaya
Concepcion Cordobes
M. J. Torres
Gara Esguevillas
Cristobalina Mayorga
Carmen Martinez
Natalia Blanca-Lopez
Gabriela Canto

Frontiers in Pharmacology

doi 10.3389/fphar.2016.00353

7,059 views
22 citations

Mini Review

Published on 21 Sep 2016

Pharmacogenomics of Prostaglandin and Leukotriene Receptors

in Pharmacogenetics and Pharmacogenomics

José A. Cornejo-García
James R. Perkins
Raquel Jurado-Escobar
Elena García-Martín
José A. Agúndez
Enrique Viguera
Natalia Pérez-Sánchez
Natalia Blanca-López

Frontiers in Pharmacology

doi 10.3389/fphar.2016.00316

9,502 views
37 citations

Review

Published on 08 Sep 2016

From Metabonomics to Pharmacometabonomics: The Role of Metabolic Profiling in Personalized Medicine

in Pharmacogenetics and Pharmacogenomics

Jeremy R. Everett

Frontiers in Pharmacology

doi 10.3389/fphar.2016.00297

10,666 views
52 citations

Original Research

Published on 29 Aug 2016

Photosensitivity to Triflusal: Formation of a Photoadduct with Ubiquitin Demonstrated by Photophysical and Proteomic Techniques

in Pharmacogenetics and Pharmacogenomics

Edurne Nuin
Dolores Pérez-Sala
Virginie Lhiaubet-Vallet
Inmaculada Andreu
Miguel A. Miranda

Frontiers in Pharmacology

doi 10.3389/fphar.2016.00277

2,986 views
10 citations

Original Research

Published on 26 Aug 2016

Killer Immunoglobulin-Like Receptor Profiles Are not Associated with Risk of Amoxicillin-Clavulanate–Induced Liver Injury in Spanish Patients

in Pharmacogenetics and Pharmacogenomics

Camilla Stephens
Antonia Moreno-Casares
Miguel-Ángel López-Nevot
Miren García-Cortés
Inmaculada Medina-Cáliz
Hacibe Hallal
German Soriano
Eva Roman
Francisco Ruiz-Cabello
Manuel Romero-Gomez

Frontiers in Pharmacology

doi 10.3389/fphar.2016.00280

3,468 views
3 citations

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Articles

A Novel Sensitive Method to Measure Catechol-O-Methyltransferase Activity Unravels the Presence of This Activity in Extracellular Vesicles Released by Rat Hepatocytes

Rivaroxaban-Induced Hemorrhage Associated with ABCB1 Genetic Defect

Pharmacogenomic Study Reveals New Variants of Drug Metabolizing Enzyme and Transporter Genes Associated with Steady-State Plasma Concentrations of Risperidone and 9-Hydroxyrisperidone in Thai Autism Spectrum Disorder Patients

Cysteinyl Leukotrienes Pathway Genes, Atopic Asthma and Drug Response: From Population Isolates to Large Genome-Wide Association Studies

Pregnane X Receptor (PXR)-Mediated Gene Repression and Cross-Talk of PXR with Other Nuclear Receptors via Coactivator Interactions

Impact of CYP2C19 Variants on Clinical Efficacy of Clopidogrel and 1-Year Clinical Outcomes in Coronary Heart Patients Undergoing Percutaneous Coronary Intervention

Age-Dependent Hepatic UDP-Glucuronosyltransferase Gene Expression and Activity in Children

Introduction of an N-Glycosylation Site into UDP-Glucuronosyltransferase 2B3 Alters Its Sensitivity to Cytochrome P450 3A1-Dependent Modulation

Pharmacometabolomics Informs Viromics toward Precision Medicine

Structure and Protein–Protein Interactions of Human UDP-Glucuronosyltransferases

Pharmacogenetics and Predictive Testing of Drug Hypersensitivity Reactions

FCERI and Histamine Metabolism Gene Variability in Selective Responders to NSAIDS

Pharmacogenomics of Prostaglandin and Leukotriene Receptors

From Metabonomics to Pharmacometabonomics: The Role of Metabolic Profiling in Personalized Medicine

Photosensitivity to Triflusal: Formation of a Photoadduct with Ubiquitin Demonstrated by Photophysical and Proteomic Techniques

Killer Immunoglobulin-Like Receptor Profiles Are not Associated with Risk of Amoxicillin-Clavulanate–Induced Liver Injury in Spanish Patients