Brief Research Report

Published on 16 Jun 2021

ABCB1 and ABCG2 Together Limit the Distribution of ABCB1/ABCG2 Substrates to the Human Retina and the ABCG2 Single Nucleotide Polymorphism Q141K (c.421C> A) May Lead to Increased Drug Exposure

in Pharmacogenetics and Pharmacogenomics

Myriam El Biali
Rudolf Karch
Cécile Philippe
Helmuth Haslacher
Nicolas Tournier
Marcus Hacker
Markus Zeitlinger
Doreen Schmidl
Oliver Langer
Martin Bauer

Frontiers in Pharmacology

doi 10.3389/fphar.2021.698966

3,114 views
6 citations

Correction

Published on 10 Jun 2021

Corrigendum: Cinical, Metabolic, and Genetic Analysis and Follow-Up of Eight Patients With HIBCH Mutations Presenting With Leigh/Leigh-Like Syndrome

in Pharmacogenetics and Pharmacogenomics

Junling Wang
Zhimei Liu
Manting Xu
Xiaodi Han
Changhong Ren
Xinying Yang
Chunhua Zhang
Fang Fang

Frontiers in Pharmacology

doi 10.3389/fphar.2021.686933

1,291 views

Original Research

Published on 09 Jun 2021

Role of Common Genetic Variants for Drug-Resistance to Specific Anti-Seizure Medications

in Pharmacogenetics and Pharmacogenomics

Stefan Wolking
Ciarán Campbell
Caragh Stapleton
Mark McCormack
Norman Delanty
Chantal Depondt
Michael R. Johnson
Bobby P. C. Koeleman
Roland Krause
Wolfram S. Kunz

Frontiers in Pharmacology

doi 10.3389/fphar.2021.688386

7,283 views
11 citations

Review

Published on 09 Jun 2021

From Genome to Drugs: New Approaches in Antimicrobial Discovery

in Pharmacogenetics and Pharmacogenomics

Federico Serral
Florencia A. Castello
Ezequiel J. Sosa
Agustín M. Pardo
Miranda Clara Palumbo
Carlos Modenutti
María Mercedes Palomino
Alberto Lazarowski
Jerónimo Auzmendi
Pablo Ivan P. Ramos

Frontiers in Pharmacology

doi 10.3389/fphar.2021.647060

11,679 views
27 citations

Original Research

Published on 07 Jun 2021

Comparative Analysis for the Performance of Long-Read-Based Structural Variation Detection Pipelines in Tandem Repeat Regions

in Pharmacogenetics and Pharmacogenomics

Mingkun Guo
Shihai Li
Yifan Zhou
Menglong Li
Zhining Wen

Frontiers in Pharmacology

doi 10.3389/fphar.2021.658072

2,650 views
3 citations

Original Research

Published on 03 Jun 2021

Theragnosis for Duchenne Muscular Dystrophy

in Pharmacogenetics and Pharmacogenomics

Leonela Luce
Micaela Carcione
Chiara Mazzanti
Paula I. Buonfiglio
Viviana Dalamón
Lilia Mesa
Alberto Dubrovsky
José Corderí
Florencia Giliberto

Frontiers in Pharmacology

doi 10.3389/fphar.2021.648390

5,272 views
6 citations

Case Report

Published on 28 May 2021

Case Report of Novel Genetic Variant in KCNT1 Channel and Pharmacological Treatment With Quinidine. Precision Medicine in Refractory Epilepsy

in Pharmacogenetics and Pharmacogenomics

M. C. Kravetz
M. S. Viola
J. Prenz
M. Curi
G. F. Bramuglia
S. Tenembaum

Frontiers in Pharmacology

doi 10.3389/fphar.2021.648519

4,184 views
6 citations

Original Research

Published on 26 May 2021

HLA Risk Alleles in Aromatic Antiepileptic Drug-Induced Maculopapular Exanthema

in Pharmacogenetics and Pharmacogenomics

Yi-Wu Shi
Jie Wang
Fu-Li Min
Wen-Jun Bian
Bi-Jun Mao
Yong Mao
Bing Qin
Bing-Mei Li
Yang-Mei Ou
Yun-Qi Hou

Frontiers in Pharmacology

doi 10.3389/fphar.2021.671572

5,206 views
9 citations

Original Research

Published on 21 May 2021

Effects of Genetic Polymorphism in CYP2D6, CYP2C19, and the Organic Cation Transporter OCT1 on Amitriptyline Pharmacokinetics in Healthy Volunteers and Depressive Disorder Patients

in Pharmacogenetics and Pharmacogenomics

Johannes Matthaei
Jürgen Brockmöller
Werner Steimer
Konstanze Pischa
Stefan Leucht
Maria Kullmann
Ole Jensen
Typhaine Ouethy
Mladen Vassilev Tzvetkov
Muhammad Rafehi

Frontiers in Pharmacology

doi 10.3389/fphar.2021.688950

8,158 views
17 citations

Original Research

Published on 21 May 2021

MicroRNA-33b is a Potential Non-Invasive Biomarker for Response to Atorvastatin Treatment in Chilean Subjects With Hypercholesterolemia: A Pilot Study

in Pharmacogenetics and Pharmacogenomics

Carmen Gloria Ubilla
Yalena Prado
Jeremy Angulo
Ignacio Obreque
Isis Paez
Nicolás Saavedra
Kathleen Saavedra
Tomás Zambrano
Luis A. Salazar

Frontiers in Pharmacology

doi 10.3389/fphar.2021.674252

2,453 views
6 citations

Original Research

Published on 19 May 2021

Pharmacogenetic Associations Between Atazanavir/UGT1A1*28 and Efavirenz/rs3745274 (CYP2B6) Account for Specific Adverse Reactions in Chilean Patients Undergoing Antiretroviral Therapy

in Pharmacogenetics and Pharmacogenomics

Daniela Poblete
Fernando Bernal
Gabriel Llull
Sebastian Archiles
Patricia Vasquez
Leonardo Chanqueo
Nicole Soto
María A. Lavanderos
Luis A. Quiñones
Nelson M. Varela

Frontiers in Pharmacology

doi 10.3389/fphar.2021.660965

4,497 views
6 citations

Original Research

Published on 18 May 2021

Association Between Genetic Polymorphisms of Metabolic Enzymes and Azathioprine-Induced Myelosuppression in 1,419 Chinese Patients: A Retrospective Study

in Pharmacogenetics and Pharmacogenomics

Zhao-Yang Chen
Yang-Hui Zhu
Ling-Yan Zhou
Wei-Qiao Shi
Zhou Qin
Bin Wu
Yu Yan
Yu-Wen Pei
Ning-Ning Chao
Rui Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2021.672769

4,399 views
15 citations

Original Research

Published on 07 May 2021

CYP2D6 in the Brain: Potential Impact on Adverse Drug Reactions in the Central Nervous System—Results From the ADRED Study

in Pharmacogenetics and Pharmacogenomics

Katja S. Just
Harald Dormann
Mathias Freitag
Marlen Schurig
Miriam Böhme
Michael Steffens
Catharina Scholl
Thomas Seufferlein
Ingo Graeff
Matthias Schwab

Frontiers in Pharmacology

doi 10.3389/fphar.2021.624104

15,246 views
11 citations

Original Research

Published on 07 May 2021

Effects of a Common Eight Base Pairs Duplication at the Exon 7-Intron 7 Junction on Splicing, Expression, and Function of OCT1

in Pharmacogenetics and Pharmacogenomics

Sarah Römer
Marleen J. Meyer
Kathrin Klein
Lennart V. Schneider
Johannes Matthaei
Ana Tzvetkova
Joanna Łapczuk-Romańska
Jochen Gaedcke
Marek Droździk
Jürgen Brockmöller

Frontiers in Pharmacology

doi 10.3389/fphar.2021.661480

2,780 views
2 citations

Review

Published on 30 Apr 2021

Extracellular Vesicles: A Novel Tool Facilitating Personalized Medicine and Pharmacogenomics in Oncology

in Pharmacogenetics and Pharmacogenomics

Katja Goričar
Vita Dolžan
Metka Lenassi

Frontiers in Pharmacology

doi 10.3389/fphar.2021.671298

5,663 views
21 citations

Original Research

Published on 30 Apr 2021

Genetic Variants in Cytosolic Phospholipase A2 Associated With Nonsteroidal Anti-Inflammatory Drug–Induced Acute Urticaria/Angioedema

in Pharmacogenetics and Pharmacogenomics

Raquel Jurado-Escobar
Inmaculada Doña
José Triano-Cornejo
James R. Perkins
Natalia Pérez-Sánchez
Almudena Testera-Montes
Marina Labella
Joan Bartra
José J. Laguna
Miguel Estravís

Frontiers in Pharmacology

doi 10.3389/fphar.2021.667824

3,192 views
10 citations

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Articles

ABCB1 and ABCG2 Together Limit the Distribution of ABCB1/ABCG2 Substrates to the Human Retina and the ABCG2 Single Nucleotide Polymorphism Q141K (c.421C> A) May Lead to Increased Drug Exposure

Corrigendum: Cinical, Metabolic, and Genetic Analysis and Follow-Up of Eight Patients With HIBCH Mutations Presenting With Leigh/Leigh-Like Syndrome

Role of Common Genetic Variants for Drug-Resistance to Specific Anti-Seizure Medications

From Genome to Drugs: New Approaches in Antimicrobial Discovery

Comparative Analysis for the Performance of Long-Read-Based Structural Variation Detection Pipelines in Tandem Repeat Regions

Theragnosis for Duchenne Muscular Dystrophy

Case Report of Novel Genetic Variant in KCNT1 Channel and Pharmacological Treatment With Quinidine. Precision Medicine in Refractory Epilepsy

HLA Risk Alleles in Aromatic Antiepileptic Drug-Induced Maculopapular Exanthema

Effects of Genetic Polymorphism in CYP2D6, CYP2C19, and the Organic Cation Transporter OCT1 on Amitriptyline Pharmacokinetics in Healthy Volunteers and Depressive Disorder Patients

MicroRNA-33b is a Potential Non-Invasive Biomarker for Response to Atorvastatin Treatment in Chilean Subjects With Hypercholesterolemia: A Pilot Study

Pharmacogenetic Associations Between Atazanavir/UGT1A1*28 and Efavirenz/rs3745274 (CYP2B6) Account for Specific Adverse Reactions in Chilean Patients Undergoing Antiretroviral Therapy

Association Between Genetic Polymorphisms of Metabolic Enzymes and Azathioprine-Induced Myelosuppression in 1,419 Chinese Patients: A Retrospective Study

CYP2D6 in the Brain: Potential Impact on Adverse Drug Reactions in the Central Nervous System—Results From the ADRED Study

Effects of a Common Eight Base Pairs Duplication at the Exon 7-Intron 7 Junction on Splicing, Expression, and Function of OCT1

Extracellular Vesicles: A Novel Tool Facilitating Personalized Medicine and Pharmacogenomics in Oncology

Genetic Variants in Cytosolic Phospholipase A2 Associated With Nonsteroidal Anti-Inflammatory Drug–Induced Acute Urticaria/Angioedema