Original Research

Published on 19 Jan 2023

A CYPome-wide study reveals new potential players in the pathogenesis of Parkinson’s disease

in Pharmacogenetics and Pharmacogenomics

Philip Hartz
Tobias Fehlmann
Gudrun Wagenpfeil
Marcus Michael Unger
Rita Bernhardt

Frontiers in Pharmacology

doi 10.3389/fphar.2022.1094265

4,508 views
8 citations

Clinical Trial

Published on 18 Jan 2023

Personalized antiplatelet therapy guided by clopidogrel pharmacogenomics in acute ischemic stroke and transient ischemic attack: A prospective, randomized controlled trial

in Pharmacogenetics and Pharmacogenomics

Xiaoguang Zhang
Shanshan Jiang
Jie Xue
Ying Ding
Jingyu Gu
Liang Hu
Xushen Xu
Zhizhang Li
Yuming Kong
Youmei Li

Frontiers in Pharmacology

doi 10.3389/fphar.2022.931405

3,982 views
7 citations

Original Research

Published on 12 Jan 2023

Comprehensive in vitro and in silico assessments of metabolic capabilities of 24 genomic variants of CYP2C19 using two different substrates

in Pharmacogenetics and Pharmacogenomics

Myung-Eui Seo
Byung-Joo Min
Nayoon Heo
Kye Hwa Lee
Ju Han Kim

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1055991

2,072 views
1 citation

Original Research

Published on 09 Jan 2023

Genome-wide analyses of platinum-induced ototoxicity in childhood cancer patients: Results of GO-CAT and United Kingdom MAGIC consortia

in Pharmacogenetics and Pharmacogenomics

Evelien G. E. Hurkmans
Marije J. Klumpers
Cinzia Dello Russo
Ward De Witte
Henk-Jan Guchelaar
Hans Gelderblom
Anne-Marie Cleton-Jansen
Sita H. Vermeulen
Suzanne Kaal
Winette T. A. van der Graaf

Frontiers in Pharmacology

doi 10.3389/fphar.2022.980309

2,893 views
1 citation

Original Research

Published on 22 Dec 2022

Methylome-wide association study of different responses to risperidone in schizophrenia

in Pharmacogenetics and Pharmacogenomics

Huihui Du
Jingsong Ma
Wei Zhou
Mo Li
Cong Huai
Lu Shen
Hao Wu
Xianglong Zhao
Na Zhang
Songyin Gao

Frontiers in Pharmacology

doi 10.3389/fphar.2022.1078464

2,652 views
1 citation

Review

Published on 21 Dec 2022

Triplex-forming oligonucleotides as an anti-gene technique for cancer therapy

in Pharmacogenetics and Pharmacogenomics

Chun Li
Zunzhen Zhou
Chao Ren
Yi Deng
Feng Peng
Qiongfen Wang
Hong Zhang
Yuan Jiang

Frontiers in Pharmacology

doi 10.3389/fphar.2022.1007723

6,303 views
15 citations

Original Research

Published on 13 Dec 2022

Identification and drug metabolic characterization of four new CYP2C9 variants CYP2C972-75 in the Chinese Han population

in Pharmacogenetics and Pharmacogenomics

Fang-Ling Zhao
Qing Zhang
Shuang-Hu Wang
Yun Hong
Shan Zhou
Quan Zhou
Pei-Wu Geng
Qing-Feng Luo
Jie-Fu Yang
Hao Chen

Frontiers in Pharmacology

doi 10.3389/fphar.2022.1007268

2,992 views
5 citations

Review

Published on 05 Dec 2022

Targeting cancer-related inflammation with non-steroidal anti-inflammatory drugs: Perspectives in pharmacogenomics

in Pharmacogenetics and Pharmacogenomics

Hongjin Lai
Yi Liu
Juan Wu
Jie Cai
Hui Jie
Yuyang Xu
Senyi Deng

Frontiers in Pharmacology

doi 10.3389/fphar.2022.1078766

4,966 views
11 citations

Clinical Trial

Published on 05 Dec 2022

Effects of CYP3A4*22 and CYP3A5 on clinical outcome in patients treated with ticagrelor for ST-segment elevation myocardial infarction: POPular Genetics sub-study

in Pharmacogenetics and Pharmacogenomics

Jaouad Azzahhafi
Thomas O. Bergmeijer
Wout W. A. van den Broek
Dean R. P. P. Chan Pin Yin
Senna Rayhi
Joyce Peper
Willem L. Bor
Daniel M. F. Claassens
Ron H. N. van Schaik
Jurriën M. ten Berg

Frontiers in Pharmacology

doi 10.3389/fphar.2022.1032995

2,014 views
2 citations

Original Research

Published on 25 Nov 2022

Associations of HLA-A and HLA-B with vancomycin-induced drug reaction with eosinophilia and systemic symptoms in the Han-Chinese population

in Pharmacogenetics and Pharmacogenomics

Chuang-Wei Wang
Wei-Chen Lin
Wei-Ti Chen
Chun-Bing Chen
Chun-Wei Lu
Hsin-Han Hou
Rosaline Chung-Yee Hui
Jennifer Wu
Chih-Jung Chang
Ya-Ching Chang

Frontiers in Pharmacology

doi 10.3389/fphar.2022.954596

3,295 views
6 citations

Original Research

Published on 24 Nov 2022

Eight pharmacokinetic genetic variants are not associated with the risk of bleeding from direct oral anticoagulants in non-valvular atrial fibrillation patients

in Pharmacogenetics and Pharmacogenomics

Alessandra M. Campos-Staffico
Michael P. Dorsch
Geoffrey D. Barnes
Hao-Jie Zhu
Nita A. Limdi
Jasmine A. Luzum

Frontiers in Pharmacology

doi 10.3389/fphar.2022.1007113

3,628 views
8 citations

Original Research

Published on 21 Nov 2022

Genotyping for HLA risk alleles versus patch tests to diagnose anti-seizure medication induced cutaneous adverse drug reactions

in Pharmacogenetics and Pharmacogenomics

Lisanne E. N. Manson
Patricia C. Y. Chan
Stefan Böhringer
Henk-Jan Guchelaar

Frontiers in Pharmacology

doi 10.3389/fphar.2022.1061419

2,643 views
2 citations

Original Research

Published on 17 Nov 2022

Identification of SNPs associated with methotrexate treatment outcomes in patients with early rheumatoid arthritis

in Pharmacogenetics and Pharmacogenomics

Shrikant S. Kolan
Gaoyang Li
Franco Grimolizzi
Joe Sexton
Guro Goll
Tore K. Kvien
Nina Paulshus Sundlisæter
Manuela Zucknick
Siri Lillegraven
Espen A. Haavardsholm

Frontiers in Pharmacology

doi 10.3389/fphar.2022.1075603

3,330 views
3 citations

Mini Review

Published on 15 Nov 2022

Global perspectives on CYP2D6 associations with primaquine metabolism and Plasmodium vivax radical cure

in Pharmacogenetics and Pharmacogenomics

Jasmine M. Olvany
Scott M. Williams
Peter A. Zimmerman

Frontiers in Pharmacology

doi 10.3389/fphar.2022.752314

2,375 views
2 citations

Editorial

Published on 11 Nov 2022

Editorial: Translation and implementation of pharmacogenomic testing in daily clinical practice: Considering current challenges and future needs

in Pharmacogenetics and Pharmacogenomics

Wojciech Miltyk
George P. Patrinos
Celine Verstuyft
Marieke Coenen
Alireza Tafazoli

Frontiers in Pharmacology

doi 10.3389/fphar.2022.1053027

1,664 views

Editorial

Published on 11 Nov 2022

Editorial: Pharmacogenomics in neglected populations

in Pharmacogenetics and Pharmacogenomics

Mariana R. Botton
Jorge Duconge
Fernanda Rodrigues-Soares

Frontiers in Pharmacology

doi 10.3389/fphar.2022.1081117

1,713 views
2 citations

Navigation group

Articles

A CYPome-wide study reveals new potential players in the pathogenesis of Parkinson’s disease

Personalized antiplatelet therapy guided by clopidogrel pharmacogenomics in acute ischemic stroke and transient ischemic attack: A prospective, randomized controlled trial

Comprehensive in vitro and in silico assessments of metabolic capabilities of 24 genomic variants of CYP2C19 using two different substrates

Genome-wide analyses of platinum-induced ototoxicity in childhood cancer patients: Results of GO-CAT and United Kingdom MAGIC consortia

Methylome-wide association study of different responses to risperidone in schizophrenia

Triplex-forming oligonucleotides as an anti-gene technique for cancer therapy

Identification and drug metabolic characterization of four new CYP2C9 variants CYP2C972-75 in the Chinese Han population

Targeting cancer-related inflammation with non-steroidal anti-inflammatory drugs: Perspectives in pharmacogenomics

Effects of CYP3A4*22 and CYP3A5 on clinical outcome in patients treated with ticagrelor for ST-segment elevation myocardial infarction: POPular Genetics sub-study

Associations of HLA-A and HLA-B with vancomycin-induced drug reaction with eosinophilia and systemic symptoms in the Han-Chinese population

Eight pharmacokinetic genetic variants are not associated with the risk of bleeding from direct oral anticoagulants in non-valvular atrial fibrillation patients

Genotyping for HLA risk alleles versus patch tests to diagnose anti-seizure medication induced cutaneous adverse drug reactions

Identification of SNPs associated with methotrexate treatment outcomes in patients with early rheumatoid arthritis

Global perspectives on CYP2D6 associations with primaquine metabolism and Plasmodium vivax radical cure

Editorial: Translation and implementation of pharmacogenomic testing in daily clinical practice: Considering current challenges and future needs

Editorial: Pharmacogenomics in neglected populations

Navigation group

Articles

A CYPome-wide study reveals new potential players in the pathogenesis of Parkinson’s disease

Personalized antiplatelet therapy guided by clopidogrel pharmacogenomics in acute ischemic stroke and transient ischemic attack: A prospective, randomized controlled trial

Comprehensive in vitro and in silico assessments of metabolic capabilities of 24 genomic variants of CYP2C19 using two different substrates

Genome-wide analyses of platinum-induced ototoxicity in childhood cancer patients: Results of GO-CAT and United Kingdom MAGIC consortia

Methylome-wide association study of different responses to risperidone in schizophrenia

Triplex-forming oligonucleotides as an anti-gene technique for cancer therapy

Identification and drug metabolic characterization of four new CYP2C9 variants CYP2C9*72-*75 in the Chinese Han population

Targeting cancer-related inflammation with non-steroidal anti-inflammatory drugs: Perspectives in pharmacogenomics

Effects of CYP3A4*22 and CYP3A5 on clinical outcome in patients treated with ticagrelor for ST-segment elevation myocardial infarction: POPular Genetics sub-study

Associations of HLA-A and HLA-B with vancomycin-induced drug reaction with eosinophilia and systemic symptoms in the Han-Chinese population

Eight pharmacokinetic genetic variants are not associated with the risk of bleeding from direct oral anticoagulants in non-valvular atrial fibrillation patients

Genotyping for HLA risk alleles versus patch tests to diagnose anti-seizure medication induced cutaneous adverse drug reactions

Identification of SNPs associated with methotrexate treatment outcomes in patients with early rheumatoid arthritis

Global perspectives on CYP2D6 associations with primaquine metabolism and Plasmodium vivax radical cure

Editorial: Translation and implementation of pharmacogenomic testing in daily clinical practice: Considering current challenges and future needs

Editorial: Pharmacogenomics in neglected populations

Identification and drug metabolic characterization of four new CYP2C9 variants CYP2C972-75 in the Chinese Han population