Frontiers in Pharmacology | Pharmacogenetics and Pharmacogenomics

Original Research

Accepted on 18 Apr 2025

The impact of CYP2C9, VKORC1, and CYP4F2 polymorphisms on warfarin dose requirement in Saudi patients

in Pharmacogenetics and Pharmacogenomics

Salha Jokhab
MAHA Meshal ALRASHEED
Dana Bakheet
Abdulkareem Almomen
Nouf Alaboud
Farhad Kamali

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1547142

Case Report

Accepted on 15 Apr 2025

The role of endoplasmic reticulum aminopeptidase ERAP2 pathogenic mutation rs1363907 in amoxicillin clavulanate-induced liver injury: A Special Case Report

in Pharmacogenetics and Pharmacogenomics

Ji-Ye Yin
Yan Zhan
Jin-Mao Liao
Ling Ye
Long Zhang
Zheng Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1564124

Original Research

Published on 14 Apr 2025

Global analysis of actionable genomic alterations in thyroid cancer and precision-based pharmacogenomic strategies

in Pharmacogenetics and Pharmacogenomics

Samantha Espinoza-Ferrao
Gabriela Echeverría-Garcés
Sebastián Rivera-Orellana
José Bueno-Miño
Emilia Castellanos-Molina
Melanie Benítez-Núñez
Andrés López-Cortés

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1524623

309 views

Methods

Published on 11 Apr 2025

Bioinformatic challenges for pharmacogenomic study: tools for genomic data analysis

in Pharmacogenetics and Pharmacogenomics

Mariamena Arbitrio
Marianna Milano
Maria Lucibello
Emanuela Altomare
Nicoletta Staropoli
Pierfrancesco Tassone
Pierosandro Tagliaferri
Mario Cannataro
Giuseppe Agapito

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1548991

611 views

Original Research

Accepted on 09 Apr 2025

Genetic Polymorphisms in SLC5A2 are Associated with Clinical Outcomes and Dapagliflozin Response in Heart Failure Patients

in Pharmacogenetics and Pharmacogenomics

Ahmed Essam Abou Warda
Rylie M. Flohr
Rania M. Sarhan
Mohamed Nabil Salem
Heba F. Salem
Ayman N. Moharram
Abdullah S Alanazi
Christelle Lteif
Brian E. Gawronski
Leanne Dumeny

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1539870

136 views

Original Research

Published on 07 Apr 2025

Evaluating the role of astragalus polysaccharide in modulating immune infiltration and enhancing prognostic biomarkers in pediatric acute myeloid leukemia

in Pharmacogenetics and Pharmacogenomics

Min-Hui He
Xian-Hui Zhang
Ji-Hong Zhang
Jie Pan
Chao Yang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1538888

223 views

Original Research

Published on 01 Apr 2025

Pharmacogenetics polygenic response score predicts outcomes in aspirin-treated stroke patients

in Pharmacogenetics and Pharmacogenomics

Rui-Nan Ma
Dong Zhang
Zhi-Zhang Li
Ying Ding
Xiao-Guang Zhang
Jie Xue
Dan-Zhuoma Ci
Yue-Ying Bai
Liang Hu
Dai-Zhan Zhou

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1519383

315 views

Original Research

Accepted on 31 Mar 2025

Unveiling the Heritability of Unexplored Pharmacogenetic Markers in Saudi Population

in Pharmacogenetics and Pharmacogenomics

Mohammad A. Alshabeeb
Deemah Alwadaani
Sireen Abdulrahim Shilbayeh
Fatemah Alherz
Ali Alghubayshi

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1559399

696 views

Correction

Published on 31 Mar 2025

Corrigendum: A pharmacogenetically-guided acenocoumarol dosing algorithm for Chilean patients: a discovery cohort study

in Pharmacogenetics and Pharmacogenomics

Angela Roco
Elena Nieto
Marcelo Suárez
Mario Rojo
Maria Paz Bertoglia
Gabriel Verón
Francisca Tamayo
Annabella Arredondo
Daniela Cruz
Jessica Muñoz

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1588440

226 views

Brief Research Report

Published on 28 Mar 2025

Balance of care activity after EMA recommendation for DPYD gene testing in Galicia

in Pharmacogenetics and Pharmacogenomics

Almudena Gil-Rodríguez
Sheila Recarey-Rama
Ana Rodríguez-Viyuela
Francisco Barros
Angel Carracedo
Olalla Maroñas

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1523536

527 views
1 citation

Editorial

Published on 26 Mar 2025

Editorial: State‐of‐the‐art hypothesis-driven systems pharmacology and artificial intelligence approaches to decipher disease complexity

in Pharmacogenetics and Pharmacogenomics

Cristina Correia
Choong-Yong Ung
Hu Li
James C. Costello

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1593164

381 views

Correction

Published on 26 Mar 2025

Corrigendum: Exploring perceived barriers and attitudes in young adults towards antidepressant pharmacotherapy, including the implementation of pharmacogenetic testing to optimize prescription practices

in Pharmacogenetics and Pharmacogenomics

Bradley Roberts
Zahra Cooper
Georgia Landery
Susanne Stanley
Bernadette T. Majda
Khan R. L. Collins
P. Anthony Akkari
Sean D. Hood
Jennifer Rodger

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1590955

269 views

Original Research

Published on 25 Mar 2025

Multigenetic pharmacogenomics–guided treatment shows greater improvements on motor symptoms compared to usual therapy in Parkinson’s disease: a small real-word prospective cohort study

in Pharmacogenetics and Pharmacogenomics

Yifan Li
Mao Li
Miao Wang
Jiarui Yao
Fengzhu Li
Siyu Chen
Xi Yin
Zhongbao Gao

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1502379

513 views

Review

Published on 20 Mar 2025

Deciphering gene mutations in the efficacy and toxicity of antineoplastic drugs: an oncology pharmacist’s perspective

in Pharmacogenetics and Pharmacogenomics

Yucai Jiang
Guolin Alexander Wen

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1574010

711 views

Original Research

Published on 19 Mar 2025

Impact of CYP3A4 and ABCB1 genetic variants on tacrolimus dosing in Greek kidney transplant recipients

in Pharmacogenetics and Pharmacogenomics

Anna Tsironi
Konstantinos Lazaros
Effrosyni Mendrinou
Marios Papasotiriou
Stavroula Siamoglou
Kyriaki Kydonopoulou
Anne John
Alexandra Gerou
Spyridon Gerou
Bassam R. Ali

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1538432

972 views

Editorial

Published on 17 Mar 2025

Editorial: Multi-omics technology: revealing the pathogenesis of diseases and the mechanism of drug efficacy of major diseases such as nutritional metabolism disorders and mental disorders

in Pharmacogenetics and Pharmacogenomics

Wenzhi Hao
Tianhao Liu
Xiliang Du
Gabriel Tao

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1586223

324 views