Frontiers in Pharmacology | Pharmacogenetics and Pharmacogenomics

Original Research

Accepted on 13 Jan 2025

Deciphering the Heterogeneity and Plasticity of the Tumor Microenvironment in Liver Cancer Provides Insights for Prognosis

in Pharmacogenetics and Pharmacogenomics

Yihao Sun
Guojuan Shi
Jian Yang
Chun-Zhong Zhou
Chuhan Peng
Yu-Hong Luo
Ying Pan
Rui-Qi Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1495280

Review

Accepted on 13 Jan 2025

Uncovering the role of microRNAs in esophageal cancer: from pathogenesis to clinical applications

in Pharmacogenetics and Pharmacogenomics

Zhenglin He
Yishuo Ji
Yutong Yuan
Tianfang Liang
Chenglin Liu
Yiping Jiao
Yimeng Chen
Yiming Yang
Liang Han
Yue Hu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1532558

Original Research

Published on 07 Jan 2025

Pharmacogenetic and pharmacokinetic factors for dexmedetomidine-associated hemodynamic instability in pediatric patients

in Pharmacogenetics and Pharmacogenomics

Yanping Guan
Bilian Li
Yiyu Zhang
Hao Luo
Xueding Wang
Xue Bai
Zhuoling Zheng
Yaying Huang
Wei Wei
Min Huang

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1515523

184 views

Editorial

Published on 03 Jan 2025

Editorial: Insights in pharmacogenetics and pharmacogenomics: 2023

in Pharmacogenetics and Pharmacogenomics

José A. G. Agúndez
Elena García-Martín

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1540478

125 views

Original Research

Published on 03 Jan 2025

Exploring perceived barriers and attitudes in young adults towards antidepressant pharmacotherapy, including the implementation of pharmacogenetic testing to optimize prescription practices

in Pharmacogenetics and Pharmacogenomics

Bradley Roberts
Zahra Cooper
Georgia Landery
Susanne Stanley
Bernadette T. Majda
Khan R. L. Collins
P. Anthony Akkari
Sean D. Hood
Jennifer Rodger

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1526101

271 views

Original Research

Accepted on 23 Dec 2024

Allele and genotype frequencies of variants in P450 cytochromes, transports and DNA repair enzymes in the Dominican Republic population

in Pharmacogenetics and Pharmacogenomics

Elizabeth Pérez-Duval
Berniza Calderón
Marlen Izquierdo
José Alfredo Herrera Isidrón
Elizabeth Reyes Reyes
Alejandro Herrera
Manuel Soto
Alba Beltré
Idania Rodeiro

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1494482

Original Research

Published on 20 Dec 2024

Integration of pharmacogenetic data in epic genomic module drives clinical decision support alerts

in Pharmacogenetics and Pharmacogenomics

Kimberly J. Newsom
Bradley Hall
Katherine A. Martinez
Scott Nelson
Petr Starostik
Khoa Nguyen

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1458095

908 views

Review

Published on 20 Dec 2024

Pharmacogenomics for neurodegenerative disorders - a focused review

in Pharmacogenetics and Pharmacogenomics

S. Rehan Ahmad
Md. Zeyaullah
Mohammad Suhail Khan
Abdullah M. AlShahrani
Abdelrhman A. Galaleldin Altijani
Haroon Ali
Adam Dawria
Ali Mohieldin
Mohammad Shane Alam
Awad Osman Abdalla Mohamed

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1478964

876 views

Case Report

Published on 19 Dec 2024

Severe liver injury induced by minocycline in hepatitis B patient: a Case Report

in Pharmacogenetics and Pharmacogenomics

Ran Wang
Yun Li
Xue Xia

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1516217

536 views

Review

Published on 16 Dec 2024

Pediatric flecainide pharmacogenomics: a roadmap to delivering precision-based care to pediatrics arrhythmias

in Pharmacogenetics and Pharmacogenomics

Ronald Palmen
Mollie Walton
Jonathan Wagner

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1477485

386 views

Original Research

Accepted on 12 Dec 2024

Better understanding the phenotypic effects of drugs through shared targets in genetic disease networks

in Pharmacogenetics and Pharmacogenomics

Elena Díaz Santiago
Aurelio Moya Garcia
Jesús Pérez-García
Raquel Yahyaoui
Christine Orengo
Florencio Pazos
James Richard Perkins
Juan A Ranea

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1470931

Original Research

Accepted on 12 Dec 2024

Leveraging AI to Automate Detection and Quantification of Extrachromosomal DNA (ecDNA) to Decode Drug Responses

in Pharmacogenetics and Pharmacogenomics

Kohen Goble
Aarav Mehta
Damien Guilbaud
Jacob Fessler
Jingting Chen
William Nenad
Oliver Cope
Darby Cheng
William Dennis
Nithya Gurumurthy

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1516621

Original Research

Published on 11 Dec 2024

Paromomycin targets HDAC1-mediated SUMOylation and IGF1R translocation in glioblastoma

in Pharmacogenetics and Pharmacogenomics

Zhong Min
Yuejie Guo
Luo Ning

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1490878

399 views

Brief Research Report

Published on 05 Dec 2024

Clinical implications of a gain-of-function genetic polymorphism in DPYD (rs4294451) in colorectal cancer patients treated with fluoropyrimidines

in Pharmacogenetics and Pharmacogenomics

Elena De Mattia
Jerry Polesel
Lucia Scarabel
Erika Cecchin

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1516375

662 views

Original Research

Published on 04 Dec 2024

AH-6809 mediated regulation of lung adenocarcinoma metastasis through NLRP7 and prognostic analysis of key metastasis-related genes

in Pharmacogenetics and Pharmacogenomics

Xu Feng
Wei Wu
Feifei Liu

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1486265

752 views

Original Research

Published on 03 Dec 2024

Pharmacogenomic profiling of the South Korean population: Insights and implications for personalized medicine

in Pharmacogenetics and Pharmacogenomics

Mi Seon Youn
Se Hwan Ahn
Ju Han Kim

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1476765

854 views

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Articles

Deciphering the Heterogeneity and Plasticity of the Tumor Microenvironment in Liver Cancer Provides Insights for Prognosis

Uncovering the role of microRNAs in esophageal cancer: from pathogenesis to clinical applications

Pharmacogenetic and pharmacokinetic factors for dexmedetomidine-associated hemodynamic instability in pediatric patients

Editorial: Insights in pharmacogenetics and pharmacogenomics: 2023

Exploring perceived barriers and attitudes in young adults towards antidepressant pharmacotherapy, including the implementation of pharmacogenetic testing to optimize prescription practices

Allele and genotype frequencies of variants in P450 cytochromes, transports and DNA repair enzymes in the Dominican Republic population

Integration of pharmacogenetic data in epic genomic module drives clinical decision support alerts

Pharmacogenomics for neurodegenerative disorders - a focused review

Severe liver injury induced by minocycline in hepatitis B patient: a Case Report

Pediatric flecainide pharmacogenomics: a roadmap to delivering precision-based care to pediatrics arrhythmias

Better understanding the phenotypic effects of drugs through shared targets in genetic disease networks

Leveraging AI to Automate Detection and Quantification of Extrachromosomal DNA (ecDNA) to Decode Drug Responses

Paromomycin targets HDAC1-mediated SUMOylation and IGF1R translocation in glioblastoma

Clinical implications of a gain-of-function genetic polymorphism in DPYD (rs4294451) in colorectal cancer patients treated with fluoropyrimidines

AH-6809 mediated regulation of lung adenocarcinoma metastasis through NLRP7 and prognostic analysis of key metastasis-related genes

Pharmacogenomic profiling of the South Korean population: Insights and implications for personalized medicine