Original Research

Published on 15 Dec 2022

TJ-M2010-5, a novel CNS drug candidate, attenuates acute cerebral ischemia-reperfusion injury through the MyD88/NF-κB and ERK pathway

in Neuropharmacology

Zeyang Li
Minghui Zhao
Xiaoqian Zhang
Yiran Lu
Yang Yang
Yalong Xie
Zhimiao Zou
Liang Zhou
Runshi Shang
Limin Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2022.1080438

3,417 views
5 citations

Original Research

Published on 14 Dec 2022

Heightened cocaine-seeking in male rats associates with a distinct transcriptomic profile in the medial prefrontal cortex

in Neuropharmacology

Christina R. Merritt
Ashley E. Smith
Kamil Khanipov
George Golovko
Kelly T. Dineley
Noelle C. Anastasio
Kathryn A. Cunningham

Frontiers in Pharmacology

doi 10.3389/fphar.2022.1022863

2,376 views
4 citations

Mini Review

Published on 14 Dec 2022

APC/C-Cdh1-targeted substrates as potential therapies for Alzheimer’s disease

in Neuropharmacology

Rebeca Lapresa
Jesus Agulla
Juan P. Bolaños
Angeles Almeida

Frontiers in Pharmacology

doi 10.3389/fphar.2022.1086540

3,928 views
4 citations

Original Research

Published on 13 Dec 2022

The mechanisms underlying the actions of Xuefu Zhuyu decoction pretreatment against neurological deficits after ischemic stroke in mice: The mediation of glymphatic function by aquaporin-4 and its anchoring proteins

in Neuropharmacology

Ting Yi
Ping Gao
Meng Hou
Huan Lv
Mengyuan Huang
Shanshan Gao
Jinrong He
Dongdong Yang
Weiyin Chen
Tianmin Zhu

Frontiers in Pharmacology

doi 10.3389/fphar.2022.1053253

3,332 views
10 citations

Original Research

Published on 08 Dec 2022

Gastrodin ameliorates the lipopolysaccharide-induced neuroinflammation in mice by downregulating miR-107-3p

in Neuropharmacology

Jin-Jin Song
Hui Li
Nan Wang
Xiao-Yan Zhou
Yan Liu
Zhen Zhang
Qian Feng
Yu-Ling Chen
Dan Liu
Jia Liang

Frontiers in Pharmacology

doi 10.3389/fphar.2022.1044375

3,972 views
10 citations

Original Research

Published on 06 Dec 2022

The efficacy and safety of epidural morphine/hydromorphone in the treatment of intractable postherpetic neuralgia: A single-center, double-blinded, randomized controlled, prospective, and non-inferiority study

in Neuropharmacology

Sun Yiping
Shen Jiayi
Hei Guang
Ji Yun
Ma Bingjie
Huang Xuehua
Yu Zhiyuan
Ma Pingchuan
Ma Ke

Frontiers in Pharmacology

doi 10.3389/fphar.2022.1051357

2,132 views
2 citations

Mini Review

Published on 06 Dec 2022

Altered states, alkaloids, and catatonia: Monoaminoxidase inhibitors and their role in the history of psychopharmacology

in Neuropharmacology

Octavian Buda
Sorin Hostiuc
Ovidiu Popa-Velea
Steluta Boroghina

Frontiers in Pharmacology

doi 10.3389/fphar.2022.1053534

2,129 views

Original Research

Published on 06 Dec 2022

Discovery of pyrrole derivatives as acetylcholinesterase-sparing butyrylcholinesterase inhibitor

in Neuropharmacology

Shouyuan Sun
Tao Shi
Yan Peng
Honghua Zhang
Linsheng Zhuo
Xue Peng
Qien Li
Manxia Wang
Shuzhi Wang
Zhen Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2022.1043397

1,671 views
1 citation

Editorial

Published on 01 Dec 2022

Editorial: Novel therapeutic approaches for the treatment of ocular disease, Volume II

in Neuropharmacology

Kyriaki Thermos
Stephanie C. Joachim

Frontiers in Pharmacology

doi 10.3389/fphar.2022.1104105

714 views

Editorial

Published on 30 Nov 2022

Editorial: The pharmacotherapy of depression—searching for new mechanisms and drug interactions basic and clinical research

in Neuropharmacology

Katarzyna Stachowicz
Magdalena Sowa-Kućma
Anna Tabecka-Łonczyńska

Frontiers in Pharmacology

doi 10.3389/fphar.2022.1098660

1,036 views

Mini Review

Published on 30 Nov 2022

Selective Vulnerability of the Locus Coeruleus Noradrenergic System and its Role in Modulation of Neuroinflammation, Cognition, and Neurodegeneration

in Neuropharmacology

Andrew K. Evans
Erwin Defensor
Mehrdad Shamloo

Frontiers in Pharmacology

doi 10.3389/fphar.2022.1030609

4,367 views
9 citations

Review

Published on 29 Nov 2022

Noble gas and neuroprotection: From bench to bedside

in Neuropharmacology

Haiying Yin
Zijun Chen
Hailin Zhao
Han Huang
Wenwen Liu

Frontiers in Pharmacology

doi 10.3389/fphar.2022.1028688

4,582 views
12 citations

Review

Published on 28 Nov 2022

New developments and opportunities in drugs being trialed for amyotrophic lateral sclerosis from 2020 to 2022

in Neuropharmacology

JingSi Jiang
Yan Wang
Min Deng

Frontiers in Pharmacology

doi 10.3389/fphar.2022.1054006

21,636 views
40 citations

Original Research

Published on 28 Nov 2022

Adolescent kratom exposure affects cognitive behaviours and brain metabolite profiles in Sprague-Dawley rats

in Neuropharmacology

Aiman Nadhirah Zul Aznal
Nurul Aqmar Mohamad Nor Hazalin
Zurina Hassan
Noorul Hamizah Mat
Nelson Jeng-Yeou Chear
Lay Kek Teh
Mohd Zaki Salleh
Farah Wahida Suhaimi

Frontiers in Pharmacology

doi 10.3389/fphar.2022.1057423

5,703 views
7 citations

Original Research

Published on 24 Nov 2022

Bioinformatics analysis and in vivo validation of ferroptosis-related genes in ischemic stroke

in Neuropharmacology

Chang Liu
Zhixi Li
Hongjie Xi

Frontiers in Pharmacology

doi 10.3389/fphar.2022.940260

10,151 views
14 citations

Review

Published on 24 Nov 2022

Research progress in traditional Chinese medicine in the treatment of Alzheimer’s disease and related dementias

in Neuropharmacology

Wanying Tan
Lingjun Qi
Xiaoyu Hu
Zhenghuai Tan

Frontiers in Pharmacology

doi 10.3389/fphar.2022.921794

5,703 views
18 citations

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Articles

TJ-M2010-5, a novel CNS drug candidate, attenuates acute cerebral ischemia-reperfusion injury through the MyD88/NF-κB and ERK pathway

Heightened cocaine-seeking in male rats associates with a distinct transcriptomic profile in the medial prefrontal cortex

APC/C-Cdh1-targeted substrates as potential therapies for Alzheimer’s disease

The mechanisms underlying the actions of Xuefu Zhuyu decoction pretreatment against neurological deficits after ischemic stroke in mice: The mediation of glymphatic function by aquaporin-4 and its anchoring proteins

Gastrodin ameliorates the lipopolysaccharide-induced neuroinflammation in mice by downregulating miR-107-3p

The efficacy and safety of epidural morphine/hydromorphone in the treatment of intractable postherpetic neuralgia: A single-center, double-blinded, randomized controlled, prospective, and non-inferiority study

Altered states, alkaloids, and catatonia: Monoaminoxidase inhibitors and their role in the history of psychopharmacology

Discovery of pyrrole derivatives as acetylcholinesterase-sparing butyrylcholinesterase inhibitor

Editorial: Novel therapeutic approaches for the treatment of ocular disease, Volume II

Editorial: The pharmacotherapy of depression—searching for new mechanisms and drug interactions basic and clinical research

Selective Vulnerability of the Locus Coeruleus Noradrenergic System and its Role in Modulation of Neuroinflammation, Cognition, and Neurodegeneration

Noble gas and neuroprotection: From bench to bedside

New developments and opportunities in drugs being trialed for amyotrophic lateral sclerosis from 2020 to 2022

Adolescent kratom exposure affects cognitive behaviours and brain metabolite profiles in Sprague-Dawley rats

Bioinformatics analysis and in vivo validation of ferroptosis-related genes in ischemic stroke

Research progress in traditional Chinese medicine in the treatment of Alzheimer’s disease and related dementias