Frontiers in Pharmacology | Neuropharmacology

Original Research

Published on 09 Apr 2025

Interpreting the clinical significance of multiple large-scale mitochondrial DNA deletions (MLSMD) in skeletal muscle tissue in the diagnostic evaluation of primary mitochondrial disease

in Neuropharmacology

Jing Wang
James T. Peterson
Joaquim Diego D. Santos
Ada J. S. Chan
Maria Alejandra Diaz-Miranda
Imon Rahaman
Jean Flickinger
Amy Goldstein
Emily Bogush
Elizabeth M. McCormick

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1507493

289 views

Systematic Review

Accepted on 08 Apr 2025

Re-evaluation of the Efficacy and Safety of Anti-Aβ Monoclonal Antibodies (Lecanemab/Donanemab) in the Treatment of Early Alzheimer's Disease

in Neuropharmacology

Haoyang Wang
Junying Pan
Mingming Zhang
Zende Tan

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1599048

Original Research

Accepted on 08 Apr 2025

Therapeutic Potential of a Rhein-Loaded Self-Nano Emulsifying Drug Delivery System in Ameliorating LPS-Induced Depression: Mechanistic Insights and Behavioral Outcomes

in Neuropharmacology

Sachin More
Md Abdur Rashid
Prashant Kumar Tiwari
Rohini Kharwade
Yahya Alhamhoom
Turky Omar Asar
Mohammed Kaleem
Nilesh Mahajan
Ajay Pise
Kishor Danao

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1577080

Original Research

Accepted on 08 Apr 2025

Suicidal Thoughts and Behaviors Associated with Fluoroquinolone Antibiotics: A Real-World Pharmacovigilance Analysis

in Neuropharmacology

Lijuang Yang
Congqin Chen
Lingqing Ding
Tingting Lu
Xiwen Li
Jie Xiao

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1556159

Original Research

Published on 08 Apr 2025

Computational drug repurposing in Parkinson’s disease: Omaveloxolone and cyproheptadine as promising therapeutic candidates

in Neuropharmacology

Xin Guo
Jie Wang
Hongyang Fan
Wanying Tao
Zijing Ren
Xingyue Li
Suyu Liu
Peiyang Zhou
Yingzhu Chen

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1539032

420 views

Original Research

Published on 08 Apr 2025

Protective effects of 4-HBd on blood–brain barrier integrity in MCAO/R model rats based on brain pharmacokinetic characteristics

in Neuropharmacology

Jin Feng
Qian Yang
Ming Chen
Yan Wang
Dan Luo
Dongxiong Hu
Jianjun Cheng
Xuelan Song
Xiaonan Zhou
Qingting Meng

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1528839

149 views

Original Research

Published on 08 Apr 2025

Brosimine B and the biphasic dose-response: insights into hormesis and retinal neuroprotection

in Neuropharmacology

Susanne Suely Santos Fonseca
Natacha M. S. Port’s
Gisele Priscila Soares Aguiar
Eliã P. Botelho
Nádia M. G. Couto
Wandson Braamcamp Souza Pinheiro
André Salim Khayat
Elizabeth S. Yamada
Edmar T. Costa
Chubert Bernardo C. Sena

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1558726

151 views

Editorial

Published on 08 Apr 2025

Editorial: Neuropharmacological intervention for severe mental illness and suicide prevention

in Neuropharmacology

Ewa Litwa
Stefano Comai
Agnieszka Zelek-Molik

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1599083

129 views

Original Research

Accepted on 07 Apr 2025

GluN2B influences the progression of status epilepticus by modulating calcium ion homeostasis through its interaction with CaMKIIα

in Neuropharmacology

Lin Zhang
Youshi Meng
Chaoning Liu
Lei Wei
Yuling Lu
Shouhuan Zheng
Donghua Zou
Yuan Wu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1550879

Original Research

Accepted on 07 Apr 2025

Lateral habenula astroglia modulate the potentiating antidepressant-like effects of bright light stimulation in intractable depression

in Neuropharmacology

Sarah Delcourte
Amel Bouloufa
Renaud Rovera
Elie Brunet
Hiep D Le
April E Williams
Satchidananda Panda
Rihab Azmani
Olivier Raineteau
Ouria Dkhissi-Benyahya

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1592909

Original Research

Accepted on 07 Apr 2025

Plasticity of ventral tegmental area disturbance during abstinence after repeated amphetamine exposure: restoration by selective activation of group II metabotropic glutamate receptors

in Neuropharmacology

Ornella Valenti
Katarzyna Anna Rekawek
Sophie Wieser
Petra Scholze
Stefan Boehm

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1534101

Original Research

Published on 07 Apr 2025

Global research trends in biomarkers, therapeutic targets, and drugs for amyotrophic lateral sclerosis: a bibliometric and visualization analysis

in Neuropharmacology

Na Guo
Weicheng Huang
Jianliang Huang
Ying Liu
Kai Zhu
Wei Gao

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1588968

259 views

Systematic Review

Published on 07 Apr 2025

Neuroprotective effect and possible mechanism of edaravone in rat models of spinal cord injury: a systematic review and network meta-analysis

in Neuropharmacology

Long-yun Zhou
Xiao-bo Wang
Xu-qing Chen
Ran Li
Bin-bin Yu
Meng-xiao Pan
Lu Fang
Jian Li
Xue-jun Cui
Min Yao

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1538879

164 views

Systematic Review

Accepted on 03 Apr 2025

Tailoring Dual Antiplatelet Therapy for Stroke Prevention: A Meta-Analysis of Timing, Duration, and Stroke Subtypes

in Neuropharmacology

NAIF M. ALHAWITI
Sherouk Fouda
Naser D. Alotaibi
Hassan A. Madkhali
Fahad K. Alsharef
Ashraf El-Metwally
Jamal M Alhawiti

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1516402

Review

Published on 03 Apr 2025

Engineered nanoparticles for the treatment of Alzheimer’s disease

in Neuropharmacology

Jia Jia
Shuang Zhao
Jinghan Zhao
Yun Gao

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1510798

302 views

Review

Published on 03 Apr 2025

Natural products protect against spinal cord injury by inhibiting ferroptosis: a literature review

in Neuropharmacology

Wei She
Junxiao Su
Wenji Ma
Guohai Ma
Jianfu Li
Hui Zhang
Cheng Qiu
Xingyong Li

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1557133

293 views