Frontiers in Pharmacology | Integrative and Regenerative Pharmacology

Original Research

Published on 30 Nov 2021

ERα-Targeting PROTAC as a Chemical Knockdown Tool to Investigate the Estrogen Receptor Function in Rat Menopausal Arthritis

in Integrative and Regenerative Pharmacology

Li Duan
Xiao Xu
Limei Xu
Caining Wen
Kan Ouyang
Zigang Li
Yujie Liang

Frontiers in Pharmacology

doi 10.3389/fphar.2021.764154

4,035 views
3 citations

Original Research

Published on 25 Nov 2021

Anti-Osteogenic Effect of Danshensu in Ankylosing Spondylitis: An in Vitro Study Based on Integrated Network Pharmacology

in Integrative and Regenerative Pharmacology

Jiaxiao Li
Zexin Chen
Hongbo Liao
Yanting Zhong
Junying Hua
Miaoling Su
Jiahao Li
Jinrong Xu
Liao Cui
Yang Cui

Frontiers in Pharmacology

doi 10.3389/fphar.2021.772190

3,260 views
8 citations

Original Research

Published on 24 Nov 2021

A Core Omnigenic Non-coding Trait Governing Dex-Induced Osteoporotic Effects Identified Without DEXA

in Integrative and Regenerative Pharmacology

Li Lu
Yanzhen Cai
Xiaoling Luo
Zhangting Wang
Sin Hang Fung
Huanhuan Jia
Chi Lam Yu
Wai Yee Chan
Kai Kei Miu
Wende Xiao

Frontiers in Pharmacology

doi 10.3389/fphar.2021.750959

2,560 views
2 citations

Review

Published on 23 Nov 2021

Recent Advances in Pharmacological Intervention of Osteoarthritis: A Biological Aspect

in Integrative and Regenerative Pharmacology

Jinxia Deng
Zhixian Zong
Zhanpeng Su
Haicong Chen
Jianping Huang
Yanru Niu
Huan Zhong
Bo Wei

Frontiers in Pharmacology

doi 10.3389/fphar.2021.772678

6,643 views
11 citations

Original Research

Published on 08 Nov 2021

Biomineralized Composite Liquid Crystal Fiber Scaffold Promotes Bone Regeneration by Enhancement of Osteogenesis and Angiogenesis

in Integrative and Regenerative Pharmacology

Yi Zhan
Bing Deng
Huixian Wu
Changpeng Xu
Ruiying Wang
Wenqiang Li
Zhixiong Pan

Frontiers in Pharmacology

doi 10.3389/fphar.2021.736301

2,928 views
7 citations

Original Research

Published on 04 Nov 2021

(-)-Epigallocatechin-3-gallate Ameliorates Intervertebral Disc Degeneration Through Reprogramming of the Circadian Clock

in Integrative and Regenerative Pharmacology

Liangwei Mei
Yi Zheng
Teng Ma
Bing Xia
Xue Gao
Yiming Hao
Zhuojing Luo
Jinghui Huang

Frontiers in Pharmacology

doi 10.3389/fphar.2021.753548

3,789 views
10 citations

Original Research

Published on 03 Nov 2021

Icariin Alleviates Wear Particle-Induced Periprosthetic Osteolysis via Down-Regulation of the Estrogen Receptor α-mediated NF-κB Signaling Pathway in Macrophages

in Integrative and Regenerative Pharmacology

Fu Guangtao
Wen Zhenkang
Deng Zhantao
Li Mengyuan
Li Qingtian
Ma Yuanchen
Chen Yuanfeng
Zheng Qiujian

Frontiers in Pharmacology

doi 10.3389/fphar.2021.746391

3,427 views
12 citations

Review

Published on 29 Oct 2021

Research Progress of the Role of Anthocyanins on Bone Regeneration

in Integrative and Regenerative Pharmacology

Wei Mao
Guowei Huang
Huan Chen
Liangliang Xu
Shengnan Qin
Aiguo Li

Frontiers in Pharmacology

doi 10.3389/fphar.2021.773660

7,957 views
20 citations

Review

Published on 28 Oct 2021

Bioactive Herbal Extracts of Traditional Chinese Medicine Applied with the Biomaterials: For the Current Applications and Advances in the Musculoskeletal System

in Integrative and Regenerative Pharmacology

Haotao Li
Rongjie Wu
Haiyang Yu
Qiujian Zheng
Yuanfeng Chen

Frontiers in Pharmacology

doi 10.3389/fphar.2021.778041

6,689 views
12 citations

Original Research

Published on 18 Oct 2021

Pyruvate Kinase M2 Mediates Glycolysis Contributes to Psoriasis by Promoting Keratinocyte Proliferation

in Integrative and Regenerative Pharmacology

Yun-zi Liu
Ming-yuan Xu
Xiao-yu Dai
Lang Yan
Lei Li
Rui-zhen Zhu
Li-jun Ren
Ji-qian-zhu Zhang
Xiao-fang Zhang
Jin-feng Li

Frontiers in Pharmacology

doi 10.3389/fphar.2021.765790

6,119 views
37 citations

Original Research

Published on 05 Oct 2021

Kaempferol Ameliorates the Inhibitory Activity of Dexamethasone in the Osteogenesis of MC3T3-E1 Cells by JNK and p38-MAPK Pathways

in Integrative and Regenerative Pharmacology

Baocheng Xie
Zhanwei Zeng
Shiyi Liao
Chenhui Zhou
Longhuo Wu
Daohua Xu

Frontiers in Pharmacology

doi 10.3389/fphar.2021.739326

7,710 views
40 citations

Original Research

Published on 01 Oct 2021

Network Pharmacology-Based Strategy for the Investigation of the Anti-Osteoporosis Effects and Underlying Mechanism of Zhuangguguanjie Formulation

in Integrative and Regenerative Pharmacology

Wang Gong
Xingren Chen
Tianshu Shi
Xiaoyan Shao
Xueying An
Jianghui Qin
Xiang Chen
Qing Jiang
Baosheng Guo

Frontiers in Pharmacology

doi 10.3389/fphar.2021.727808

5,002 views
4 citations

Original Research

Published on 28 Sep 2021

Nox4 Promotes RANKL-Induced Autophagy and Osteoclastogenesis via Activating ROS/PERK/eIF-2α/ATF4 Pathway

in Integrative and Regenerative Pharmacology

Jing Sun
Wugui Chen
Songtao Li
Sizhen Yang
Ying Zhang
Xu Hu
Hao Qiu
Jigong Wu
Shangcheng Xu
Tongwei Chu

Frontiers in Pharmacology

doi 10.3389/fphar.2021.751845

6,761 views
28 citations

Review

Published on 16 Sep 2021

Update on Novel Non-Operative Treatment for Osteoarthritis: Current Status and Future Trends

in Integrative and Regenerative Pharmacology

Tao Chen
Weidong Weng
Yang Liu
Romina H. Aspera-Werz
Andreas K Nüssler
Jianzhong Xu

Frontiers in Pharmacology

doi 10.3389/fphar.2021.755230

12,424 views
21 citations

Original Research

Published on 08 Sep 2021

Nicorandil Inhibits Osteoclast Formation Base on NF-κB and p-38 MAPK Signaling Pathways and Relieves Ovariectomy-Induced Bone Loss

in Integrative and Regenerative Pharmacology

Shenggui Xu
Xiankun Cao
Zhenxing Yu
Wenxin He
Yichuan Pang
Wang Lin
Zhiqian Chen
Weizhong Guo
Xiongwei Lu
Chengshou Lin

Frontiers in Pharmacology

doi 10.3389/fphar.2021.726361

2,894 views
8 citations

Review

Published on 07 Sep 2021

MicroRNA-21: An Emerging Player in Bone Diseases

in Integrative and Regenerative Pharmacology

Chen Chen
Ya-Mei Liu
Bin-Lan Fu
Liang-Liang Xu
Bin Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2021.722804

4,858 views
18 citations