Frontiers in Pharmacology | Inflammation Pharmacology

Original Research

Published on 17 Jan 2025

VASN knockout induces myocardial fibrosis in mice by downregulating non-collagen fibers and promoting inflammation

in Inflammation Pharmacology

Junming Sun
Siwei Yin
Qiurui Li
Jun Zhang
Xiaoping Guo
Na Yu
Bing Hu
Yiqiang Ouyang
Qiaojuan Huang
Min He

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1500617

106 views

Original Research

Published on 16 Jan 2025

Protective effect and mechanism of Sufentanil on acute lung injury in septic mice

in Inflammation Pharmacology

Hongqiao Hou
Bowen Jiang
Aiqing Zhu
Junjun Hou
Zhe Qu
Ruping Liu
Aiqun Li

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1514602

192 views

Original Research

Published on 14 Jan 2025

MLL-AF4 upregulates 5-lipoxygenase expression in t(4;11) leukemia cells via the ALOX5 core promoter

in Inflammation Pharmacology

Marius Hyprath
Maximilian Molitor
Ilona Schweighöfer
Rolf Marschalek
Dieter Steinhilber

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1520507

259 views

Original Research

Accepted on 13 Jan 2025

Efficacy and safety profile of biotechnological agents and Janus kinases inhibitors in VEXAS syndrome: data from the international AIDA Network VEXAS registry

in Inflammation Pharmacology

Antonio Vitale
Valeria Caggiano
Flavia Leone
Andrea Hinojosa-Azaola
Eduardo Martin-Nares
Guillermo Arturo Guaracha-Basañez
Jiram Torres-Ruiz
Perla Ayumi Kawakami-Campos
Pravin Hissaria
Alicia Callisto

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1462254

Original Research

Accepted on 13 Jan 2025

Roles of Retinoic Acid-Related Orphan Receptor α in High Glucose-Induced Cardiac Fibroblasts Proliferation

in Inflammation Pharmacology

Wenqing San
Qianyou Zhou
Danning Shen
Danyi Cao
Yun Chen
Guoliang Meng

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1539690

Original Research

Accepted on 13 Jan 2025

Cannabinoid receptor 2 selective agonist ameliorates adjuvant-induced arthritis by modulating the balance between Treg and Th17 cells

in Inflammation Pharmacology

Na Tian
Cui Yang
Yu Du
Miao Chen
Bin Li
Dan Li
Sheng-Ming Dai

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1532518

Review

Published on 13 Jan 2025

Resveratrol-driven macrophage polarization: unveiling mechanisms and therapeutic potential

in Inflammation Pharmacology

Panting Wang
Zixi Li
Yixuan Song
Bowei Zhang
Chaofeng Fan

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1516609

181 views

Original Research

Accepted on 10 Jan 2025

Zinc Regulates Microglial Polarization and Inflammation through IKBα after Spinal Cord Injury and Promotes Neuronal Repair and Motor Function Recovery in Mice

in Inflammation Pharmacology

Daoyong Li
Mingyu Bai
Zhanpeng Guo
Yang Cui
Xifan Mei
Tian He
Zhaoliang Shen

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1510372

Original Research

Accepted on 09 Jan 2025

Hydrogen-oxygen Mixture Inhalation as an Adjunctive Treatment to Home-based Exercise in Older Patients with Knee Osteoarthritis: An Open-label, Blinded-endpoint, Randomized Controlled Trial

in Inflammation Pharmacology

Chenhui Wang
Mengwei Yan
Yuru Li
Lei Han
Hongqian Wang
Shufeng Jia
Xingchen Liu
Yang Liu
Fan Wu
Baoguo Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1505922

Original Research

Published on 09 Jan 2025

Duvelisib is a novel NFAT inhibitor that mitigates adalimumab-induced immunogenicity

in Inflammation Pharmacology

Aboli Bhingarkar
Yuyin Wang
Keito Hoshitsuki
Katherine Marie Eichinger
Sanjay Rathod
Yin Zhu
He Lyu
Andrew T. McNutt
Larry W. Moreland
Lee McDermott

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1397995

319 views

Original Research

Published on 09 Jan 2025

Association of early aspirin use with 90-day mortality in patients with sepsis: an PSM analysis of the MIMIC-IV database

in Inflammation Pharmacology

Chunsheng Huang
Qiaoling Tong
Wenyuan Zhang
Zhihao Pan

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1475414

156 views

Original Research

Published on 07 Jan 2025

Oxytocin ameliorates lipopolysaccharide-induced acute orchitis model: interplay of oxidative stress and inflammatory pathways

in Inflammation Pharmacology

Mohamed El-Sherbiny
Hany A. Elkattawy
Shimaa Hadhoud
Ahmed N. Nasr
Ateya M. Ibrahim
Omar Z. Ameer
Noorhan Alsaleebi
Joud Asfari
Madaniah O. Zakari
Moaz A. Mojaddidi

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1506777

263 views

Original Research

Published on 07 Jan 2025

Ponatinib alleviates non-alcoholic steatohepatitis through TFEB-mediated autophagy

in Inflammation Pharmacology

Zhuomiao Lin
Meiqing Yang
Xihui Yu
Guozhu Tan
Jiahong Zhong

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1505768

109 views

Original Research

Published on 07 Jan 2025

Oxyberberine alleviates lipopolysaccharide-induced intestinal barrier disruption and inflammation in human colonic Caco-2 cells in vitro

in Inflammation Pharmacology

Cailan Li
Jiahao Wang
Hongmei Yang
Shuang Luo
Qiang Lu

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1496874

141 views

Original Research

Published on 07 Jan 2025

KAE ameliorates LPS-mediated acute lung injury by inhibiting PANoptosis through the intracellular DNA-cGAS-STING axis

in Inflammation Pharmacology

Yonghu Chen
Xilin Wu
Zhe Jiang
Xuezheng Li

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1461931

150 views

Original Research

Published on 06 Jan 2025

Glycyrrhizin as a potential disease-modifying therapy for epilepsy: insights into targeting pyroptosis to exert neuroprotective and anticonvulsant effects

in Inflammation Pharmacology

Lei Wei
Sijie Ou
Youshi Meng
Lanfeng Sun
Lin Zhang
Yuling Lu
Yuan Wu

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1530735

223 views

Navigation group

Articles

VASN knockout induces myocardial fibrosis in mice by downregulating non-collagen fibers and promoting inflammation

Protective effect and mechanism of Sufentanil on acute lung injury in septic mice

MLL-AF4 upregulates 5-lipoxygenase expression in t(4;11) leukemia cells via the ALOX5 core promoter

Efficacy and safety profile of biotechnological agents and Janus kinases inhibitors in VEXAS syndrome: data from the international AIDA Network VEXAS registry

Roles of Retinoic Acid-Related Orphan Receptor α in High Glucose-Induced Cardiac Fibroblasts Proliferation

Cannabinoid receptor 2 selective agonist ameliorates adjuvant-induced arthritis by modulating the balance between Treg and Th17 cells

Resveratrol-driven macrophage polarization: unveiling mechanisms and therapeutic potential

Zinc Regulates Microglial Polarization and Inflammation through IKBα after Spinal Cord Injury and Promotes Neuronal Repair and Motor Function Recovery in Mice

Hydrogen-oxygen Mixture Inhalation as an Adjunctive Treatment to Home-based Exercise in Older Patients with Knee Osteoarthritis: An Open-label, Blinded-endpoint, Randomized Controlled Trial

Duvelisib is a novel NFAT inhibitor that mitigates adalimumab-induced immunogenicity

Association of early aspirin use with 90-day mortality in patients with sepsis: an PSM analysis of the MIMIC-IV database

Oxytocin ameliorates lipopolysaccharide-induced acute orchitis model: interplay of oxidative stress and inflammatory pathways

Ponatinib alleviates non-alcoholic steatohepatitis through TFEB-mediated autophagy

Oxyberberine alleviates lipopolysaccharide-induced intestinal barrier disruption and inflammation in human colonic Caco-2 cells in vitro

KAE ameliorates LPS-mediated acute lung injury by inhibiting PANoptosis through the intracellular DNA-cGAS-STING axis

Glycyrrhizin as a potential disease-modifying therapy for epilepsy: insights into targeting pyroptosis to exert neuroprotective and anticonvulsant effects