Frontiers in Pharmacology | Gastrointestinal and Hepatic Pharmacology

Original Research

Published on 25 Nov 2024

Osteopontin neutralization increases vitamin D receptors on NKT cells and ameliorates liver fibrosis by promoting their activity

in Gastrointestinal and Hepatic Pharmacology

Johnny Amer
Ahmad Salhab
Enas Hussini
Rasha Shweiki
Iman Zahran
Mohammad Far

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1484278

1,218 views

Original Research

Published on 22 Nov 2024

p-hydroxy benzaldehyde attenuates intestinal epithelial barrier dysfunction caused by colitis via activating the HNF-1β/SLC26A3 pathway

in Gastrointestinal and Hepatic Pharmacology

Meng Liu
Yuhui Wang
Xiaotian Xu
Guoqiang Guan
Shu Zhang
Shengnan Zhu
Yang Liu
Yizhun Zhu
Xiaoqun Duan

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1448863

1,417 views
1 citation

Original Research

Published on 21 Nov 2024

ADRB2 serves as a novel biomarker and attenuates alcoholic hepatitis via the SIRT1/PGC-1α/PPARα pathway: integration of WGCNA, machine learning and experimental validation

in Gastrointestinal and Hepatic Pharmacology

Li Song
Shuo Huang
Honghao Yan
Qing Ma
Qihan Luo
Jiang Qiu
Minxia Chen
Zongyuan Li
He Jiang
Yufan Chen

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1423031

1,704 views

Original Research

Published on 20 Nov 2024

Integrated multi-omics analyses combined with western blotting discovered that cis-TSG alleviated liver injury via modulating lipid metabolism

in Gastrointestinal and Hepatic Pharmacology

Tekleab Teka
Jiang Wu
Patrick Kwabena Oduro
Ze Li
Chenxi Wang
Hao Chen
Lin Zhang
Haitao Wang
Liming Wang
Lifeng Han

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1485035

1,427 views

Original Research

Published on 13 Nov 2024

Tracing the historical foundations of infliximab in Crohn’s disease treatment: a cited reference analysis

in Gastrointestinal and Hepatic Pharmacology

Andy Wai Kan Yeung

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1498464

826 views

Original Research

Published on 13 Nov 2024

Association between different GLP-1 receptor agonists and acute pancreatitis: case series and real-world pharmacovigilance analysis

in Gastrointestinal and Hepatic Pharmacology

Hui Guo
Qian Guo
Zhiqiang Li
Ze Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1461398

3,904 views
2 citations

Original Research

Published on 08 Nov 2024

Celecoxib and rofecoxib have different effects on small intestinal ischemia/reperfusion injury in rats

in Gastrointestinal and Hepatic Pharmacology

Szilvia B. László
Barbara Hutka
András S. Tóth
Tamás Hegyes
Zsuzsanna O. Demeter
Arezoo Haghighi
Gerda Wachtl
Ágnes Kelemen
Anna Jakab
Klára Gyires

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1468579

1,105 views

Clinical Trial

Published on 08 Nov 2024

Comparison of enteral prucalopride versus intravenous metoclopramide for feeding intolerance in patients with critical illness: a randomized double-blinded study

in Gastrointestinal and Hepatic Pharmacology

Eman Mohamed Elmokadem
Dina Khaled Abou El Fadl
Nermin Eissa
Najla Abdulaziz Alnassar
Ahmed M. Bassiouny
Amir Eskander Hanna Samy
Nouran Omar El Said

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1413246

1,203 views

Original Research

Published on 07 Nov 2024

Rabeprazole suppressed gastric intestinal metaplasia through activation of GPX4-mediated ferroptosis

in Gastrointestinal and Hepatic Pharmacology

Jing Xie
Xinhua Liang
Fangfang Xie
Canxin Huang
Zijun Lin
Shuping Xie
Fangying Yang
Fengfeng Zheng
Lanlan Geng
Wanfu Xu

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1409001

1,181 views

Original Research

Published on 05 Nov 2024

Mex3a promoter hypomethylation can be utilized to diagnose HBV-associated hepatocellular carcinoma: a randomized controlled trial

in Gastrointestinal and Hepatic Pharmacology

Jie-Ru Yang
Yu-Xin Tian
Jin-E. Li
Ying Zhang
Yu-Chen Fan
Kai Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1325869

963 views

Original Research

Published on 28 Oct 2024

Modulation of Notch signaling pathway in activated hepatic stellate cells does not ameliorate the outcome of liver fibrosis in carbon tetrachloride and DDC-feeding models

in Gastrointestinal and Hepatic Pharmacology

Dino Šisl
Pavao Planinić
Sanja Novak
Maša Filipović
Darja Flegar
Alan Šućur
Petra Turčić
Nataša Kovačić
Ivo Kalajzić
Danka Grčević

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1440236

1,111 views

Review

Published on 24 Oct 2024

Flavonoids in natural products for the therapy of liver diseases: progress and future opportunities

in Gastrointestinal and Hepatic Pharmacology

Yanmei Liao
Fei Lv
Tianwen Quan
Chuan Wang
Jike Li

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1485065

1,736 views
4 citations

Original Research

Published on 24 Oct 2024

Multi-omics reveals the alleviating effect of berberine on ulcerative colitis through modulating the gut microbiome and bile acid metabolism in the gut-liver axis

in Gastrointestinal and Hepatic Pharmacology

Jingsheng Yu
Yixuan Zheng
Changmin Liu
Zhuangyuan Xie
Qingqing Liu
Shuai Yang
Qianqian Tian
Chi Song
Shilin Chen

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1494210

1,771 views
2 citations

Original Research

Published on 22 Oct 2024

GYY4137, as a slow-releasing H2S donor, ameliorates sodium deoxycholate–induced chronic intestinal barrier injury and gut microbiota dysbiosis

in Gastrointestinal and Hepatic Pharmacology

Shaorong Pan
Han Yan
Jing Zhu
Yuanyuan Ma
Pengyuan Wang
Yucun Liu
Zeyang Chen

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1476407

1,195 views

Systematic Review

Published on 17 Oct 2024

Comparative effectiveness of treatments for recurrent Clostridioides difficile infection: a network meta-analysis of randomized controlled trials

in Gastrointestinal and Hepatic Pharmacology

Hong Duo
Yanwei Yang
Guqing Zhang
Yingxin Chen
Yumeng Cao
Linjie Luo
Huaqin Pan
Qifa Ye

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1430724

2,389 views
1 citation

Original Research

Published on 16 Oct 2024

Effectiveness of biologic therapies in achieving treatment targets in inflammatory bowel disease; real-world data from the Middle East (ENROLL study)

in Gastrointestinal and Hepatic Pharmacology

Mohammad Shehab
Ahmad Alfadhli
Israa Abdullah
Wrood Alostad
Alaa Marei
Fatema Alrashed

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1388043

1,373 views
1 citation