Original Research

Published on 10 Jul 2024

Evaluation of the mechanism of action of paracetamol, drotaverine, and peppermint oil and their effects in combination with hyoscine butylbromide on colonic motility: human ex-vivo study

in Gastrointestinal and Hepatic Pharmacology

Sara Traserra
Claudia Barber
Luis Gerardo Alcalá-González
Stefania Landolfi
Robert Lange
Carolina Malagelada
Maura Corsetti
Marcel Jimenez

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1384070

1,223 views

Original Research

Published on 08 Jul 2024

FGF21-dependent alleviation of cholestasis-induced liver fibrosis by sodium butyrate

in Gastrointestinal and Hepatic Pharmacology

Jing Yang
Lei Chen
Shan-Shan Zhao
Chuang Du
Yi-Zhe Fan
Hui-Xin Liu
Yongchun Li
Yong-Zhi Li

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1422770

1,207 views
1 citation

Original Research

Published on 28 Jun 2024

A novel bioinformatics strategy to uncover the active ingredients and molecular mechanisms of Bai Shao in the treatment of non-alcoholic fatty liver disease

in Gastrointestinal and Hepatic Pharmacology

Shuaibing He
Hantao Chen
Yanfeng Yi
Diandong Hou
Xuyan Fu
Jinlu Xie
Juan Zhang
Chongbin Liu
Xiaochen Ru
Juan Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1406188

906 views

Review

Published on 24 Jun 2024

Exploring the lutein therapeutic potential in steatotic liver disease: mechanistic insights and future directions

in Gastrointestinal and Hepatic Pharmacology

Elisa Balboa
Faride Saud
Claudia Parra-Ruiz
Marjorie de la Fuente
Glauben Landskron
Silvana Zanlungo

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1406784

2,860 views

Original Research

Published on 17 Jun 2024

Ezetimibe, Niemann-Pick C1 like 1 inhibitor, modulates hepatic phospholipid metabolism to alleviate fat accumulation

in Gastrointestinal and Hepatic Pharmacology

Hyekyung Yang
Dong Ho Suh
Eun Sung Jung
Yoonjin Lee
Kwang-Hyeon Liu
In-Gu Do
Choong Hwan Lee
Cheol-Young Park

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1406493

1,038 views

Original Research

Published on 14 Jun 2024

Novel genetic alterations in liver cancer distinguish distinct clinical outcomes and combination immunotherapy responses

in Gastrointestinal and Hepatic Pharmacology

Yizhou Wang
Peipei Shang
Chang Xu
Wei Dong
Xiaofeng Zhang
Yong Xia
Chengjun Sui
Cheng Yang

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1416295

1,613 views

Review

Published on 12 Jun 2024

Ginsenosides: an immunomodulator for the treatment of colorectal cancer

in Gastrointestinal and Hepatic Pharmacology

Jianan Qian
Yanyu Jiang
Hongyi Hu

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1408993

1,341 views
1 citation

Original Research

Published on 05 Jun 2024

Quantitative evaluation of the time-course and efficacy of targeted agents for ulcerative colitis

in Gastrointestinal and Hepatic Pharmacology

Boran Yu
Siyao Jin
Jiaqi Han
Jiamin Xu
Shaolong Zhang
Yanming Li
Xiangyu Ma
Xiaoling Wang
Libo Zhao

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1399963

1,111 views

Original Research

Published on 03 Jun 2024

Untargeted metabonomics and TLR4/ NF-κB signaling pathway analysis reveals potential mechanism of action of Dendrobium huoshanense polysaccharide in nonalcoholic fatty liver disease

in Gastrointestinal and Hepatic Pharmacology

Guang-hui Deng
Chen-chen Zhao
Xiao Cai
Xiao-qian Zhang
Meng-zhen Ma
Jia-hui Lv
Wen-li Jiang
Dai-yin Peng
Yan-yan Wang
Li-hua Xing

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1374158

1,416 views
1 citation

Original Research

Published on 30 May 2024

Assessing immune hepatotoxicity of troglitazone with a versatile liver-immune-microphysiological-system

in Gastrointestinal and Hepatic Pharmacology

Quanfeng Deng
Youlong Yang
Yuangui Liu
Mengting Zou
Guiyuan Huang
Shiqi Yang
Lingyu Li
Yueyang Qu
Yong Luo
Xiuli Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1335836

1,293 views
1 citation

Original Research

Published on 27 May 2024

Gossypetin targets the liver-brain axis to alleviate pre-existing liver fibrosis and hippocampal neuroinflammation in mice

in Gastrointestinal and Hepatic Pharmacology

Cenlu Xu
Haoran Tai
Yanan Chu
Ye Liu
Jiacheng He
Yiran Wang
Bingyin Su
Shurong Li

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1385330

1,056 views

Original Research

Published on 27 May 2024

Pancreatitis with use of new diabetic medications: a real-world data study using the post-marketing FDA adverse event reporting system (FAERS) database

in Gastrointestinal and Hepatic Pharmacology

Khalidah A. Alenzi
Deemah Alsuhaibani
Bader Batarfi
Thamir M. Alshammari

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1364110

2,996 views
3 citations

Systematic Review

Published on 24 May 2024

A role for curcumin in preventing liver fibrosis in animals: a systematic review and meta-analysis

in Gastrointestinal and Hepatic Pharmacology

Bo-Hao Huang
Zi-Wei Guo
Bo-Han Lv
Xin Zhao
Yan-Bo Li
Wen-Liang Lv

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1396834

1,086 views

Editorial

Published on 23 May 2024

Editorial: Exploring the roles of probiotics/postbiotics and gut microbiota on human health

in Gastrointestinal and Hepatic Pharmacology

Cheng Chung Yong
Chyn Boon Wong

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1430857

624 views

Original Research

Published on 23 May 2024

Bacillus coagulans and Clostridium butyricum synergistically alleviate depression in a chronic unpredictable mild stress mouse model through altering gut microbiota and prefrontal cortex gene expression

in Gastrointestinal and Hepatic Pharmacology

Jingyi Xu
Lei Zhou
Zhaowei Chen
Yuezhu Wang
Fang Xu
Qun Kuang
Yixuan Zhang
Huajun Zheng

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1393874

1,396 views
1 citation

Original Research

Published on 21 May 2024

TRPC absence induces pro-inflammatory macrophage polarization to promote obesity and exacerbate colorectal cancer

in Gastrointestinal and Hepatic Pharmacology

Yanting Lin
Rui Gao
Dongquan Jing
Yiming Liu
Huijuan Da
Lutz Birnbaumer
Yong Yang
Xinghua Gao
Zhenhua Gao
Qiuhua Cao

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1392328

1,484 views

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Articles

Evaluation of the mechanism of action of paracetamol, drotaverine, and peppermint oil and their effects in combination with hyoscine butylbromide on colonic motility: human ex-vivo study

FGF21-dependent alleviation of cholestasis-induced liver fibrosis by sodium butyrate

A novel bioinformatics strategy to uncover the active ingredients and molecular mechanisms of Bai Shao in the treatment of non-alcoholic fatty liver disease

Exploring the lutein therapeutic potential in steatotic liver disease: mechanistic insights and future directions

Ezetimibe, Niemann-Pick C1 like 1 inhibitor, modulates hepatic phospholipid metabolism to alleviate fat accumulation

Novel genetic alterations in liver cancer distinguish distinct clinical outcomes and combination immunotherapy responses

Ginsenosides: an immunomodulator for the treatment of colorectal cancer

Quantitative evaluation of the time-course and efficacy of targeted agents for ulcerative colitis

Untargeted metabonomics and TLR4/ NF-κB signaling pathway analysis reveals potential mechanism of action of Dendrobium huoshanense polysaccharide in nonalcoholic fatty liver disease

Assessing immune hepatotoxicity of troglitazone with a versatile liver-immune-microphysiological-system

Gossypetin targets the liver-brain axis to alleviate pre-existing liver fibrosis and hippocampal neuroinflammation in mice

Pancreatitis with use of new diabetic medications: a real-world data study using the post-marketing FDA adverse event reporting system (FAERS) database

A role for curcumin in preventing liver fibrosis in animals: a systematic review and meta-analysis

Editorial: Exploring the roles of probiotics/postbiotics and gut microbiota on human health

Bacillus coagulans and Clostridium butyricum synergistically alleviate depression in a chronic unpredictable mild stress mouse model through altering gut microbiota and prefrontal cortex gene expression

TRPC absence induces pro-inflammatory macrophage polarization to promote obesity and exacerbate colorectal cancer