Original Research

Accepted on 14 Nov 2024

Nitazoxanide mitigates methotrexate hepatotoxicity in rats: role in inhibiting apoptosis and regulating endoplasmic reticulum stress

in Gastrointestinal and Hepatic Pharmacology

Nevertyty Mohamed Mahmoud
Shimaa Elshazly
Fatma El-Shaarawy
Sawsan A Zaitone
Afaf Aldahish
Gehan A Ahmed
Manal S Fawzy
Sheka Aloyouni
Sally Abed
Shaimaa S El-Sayed

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1491249

Original Research

Accepted on 14 Nov 2024

Assessing real-world safety of plecanatide: A pharmacovigilance study based on the FDA Adverse Event Reporting System

in Gastrointestinal and Hepatic Pharmacology

Zhiyuan Zhang
Yifan Yao
Li Zhu

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1500810

Original Research

Accepted on 14 Nov 2024

Effect of Helicobacter pylori-Related Chronic Gastritis on Gastrointestinal Microorganisms and Brain Neurotransmitters in Mice

in Gastrointestinal and Hepatic Pharmacology

Hai-Hua Liu
Tang-Tang Lin
Qi-Jia Zhang
Ling Zhang
Jin-Ying Fang
Ling Hu

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1472437

Original Research

Published on 13 Nov 2024

Tracing the historical foundations of infliximab in Crohn’s disease treatment: a cited reference analysis

in Gastrointestinal and Hepatic Pharmacology

Andy Wai Kan Yeung

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1498464

Original Research

Published on 13 Nov 2024

Association between different GLP-1 receptor agonists and acute pancreatitis: case series and real-world pharmacovigilance analysis

in Gastrointestinal and Hepatic Pharmacology

Hui Guo
Qian Guo
Zhiqiang Li
Ze Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1461398

107 views

Original Research

Accepted on 12 Nov 2024

Osteopontin neutralization increases vitamin D receptors on NKT cells and ameliorates liver fibrosis by promoting their activity

in Gastrointestinal and Hepatic Pharmacology

Johnny Amer
Ahmad Salhab
Enas Hussini
Rasha Shweiki
Iman Zahran
Mohammad Far

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1484278

Original Research

Accepted on 08 Nov 2024

ADRB2 serves as a novel biomarker and attenuates alcoholic hepatitis via the SIRT1/PGC-1α/PPARα Pathway: Integration of WGCNA, machine learning and experimental validation

in Gastrointestinal and Hepatic Pharmacology

Li Song
Shuo Huang
Qing Ma
Qihan Luo
Qiu Jiang
Honghao Yan
Zongyuan Li
He Jiang
Yufan Chen
Fangming Chen

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1423031

Original Research

Published on 08 Nov 2024

Celecoxib and rofecoxib have different effects on small intestinal ischemia/reperfusion injury in rats

in Gastrointestinal and Hepatic Pharmacology

Szilvia B. László
Barbara Hutka
András S. Tóth
Tamás Hegyes
Zsuzsanna O. Demeter
Arezoo Haghighi
Gerda Wachtl
Ágnes Kelemen
Anna Jakab
Klára Gyires

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1468579

206 views

Clinical Trial

Published on 08 Nov 2024

Comparison of enteral prucalopride versus intravenous metoclopramide for feeding intolerance in patients with critical illness: a randomized double-blinded study

in Gastrointestinal and Hepatic Pharmacology

Eman Mohamed Elmokadem
Dina Khaled Abou El Fadl
Nermin Eissa
Najla Abdulaziz Alnassar
Ahmed M. Bassiouny
Amir Eskander Hanna Samy
Nouran Omar El Said

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1413246

135 views

Original Research

Published on 07 Nov 2024

Rabeprazole suppressed gastric intestinal metaplasia through activation of GPX4-mediated ferroptosis

in Gastrointestinal and Hepatic Pharmacology

Jing Xie
Xinhua Liang
Fangfang Xie
Canxin Huang
Zijun Lin
Shuping Xie
Fangying Yang
Fengfeng Zheng
Lanlan Geng
Wanfu Xu

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1409001

145 views

Original Research

Accepted on 05 Nov 2024

Integrated multi-omics analyses discovered that cis-TSG alleviated liver injury via modulating lipid metabolism

in Gastrointestinal and Hepatic Pharmacology

Tekleab Teka Teklehaimanot
Jiang Wu
Patrick Kwabena Oduro
Ze Li
Chenxi Wang
Hao Chen
Lin Zhang
Haitao Wang
Liming Wang
Lifeng Han

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1485035

140 views

Original Research

Published on 05 Nov 2024

Mex3a promoter hypomethylation can be utilized to diagnose HBV-associated hepatocellular carcinoma: a randomized controlled trial

in Gastrointestinal and Hepatic Pharmacology

Jie-Ru Yang
Yu-Xin Tian
Jin-E. Li
Ying Zhang
Yu-Chen Fan
Kai Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1325869

121 views

Original Research

Accepted on 04 Nov 2024

p-hydroxy benzaldehyde attenuates intestinal epithelial barrier dysfunction caused by colitis via activating the HNF-1β/SLC26A3 pathway

in Gastrointestinal and Hepatic Pharmacology

Meng Liu
Yuhui Wang
Xiaotian Xu
Guoqiang Guan
Shu Zhang
Shengnan Zhu
Yang Liu
Yi Zhun ZHU
Xiaoqun Duan

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1448863

Original Research

Published on 28 Oct 2024

Modulation of Notch signaling pathway in activated hepatic stellate cells does not ameliorate the outcome of liver fibrosis in carbon tetrachloride and DDC-feeding models

in Gastrointestinal and Hepatic Pharmacology

Dino Šisl
Pavao Planinić
Sanja Novak
Maša Filipović
Darja Flegar
Alan Šućur
Petra Turčić
Nataša Kovačić
Ivo Kalajzić
Danka Grčević

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1440236

188 views

Review

Published on 24 Oct 2024

Flavonoids in natural products for the therapy of liver diseases: progress and future opportunities

in Gastrointestinal and Hepatic Pharmacology

Yanmei Liao
Fei Lv
Tianwen Quan
Chuan Wang
Jike Li

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1485065

320 views

Original Research

Published on 24 Oct 2024

Multi-omics reveals the alleviating effect of berberine on ulcerative colitis through modulating the gut microbiome and bile acid metabolism in the gut-liver axis

in Gastrointestinal and Hepatic Pharmacology

Jingsheng Yu
Yixuan Zheng
Changmin Liu
Zhuangyuan Xie
Qingqing Liu
Shuai Yang
Qianqian Tian
Chi Song
Shilin Chen

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1494210

207 views

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Articles

Nitazoxanide mitigates methotrexate hepatotoxicity in rats: role in inhibiting apoptosis and regulating endoplasmic reticulum stress

Assessing real-world safety of plecanatide: A pharmacovigilance study based on the FDA Adverse Event Reporting System

Effect of Helicobacter pylori-Related Chronic Gastritis on Gastrointestinal Microorganisms and Brain Neurotransmitters in Mice

Tracing the historical foundations of infliximab in Crohn’s disease treatment: a cited reference analysis

Association between different GLP-1 receptor agonists and acute pancreatitis: case series and real-world pharmacovigilance analysis

Osteopontin neutralization increases vitamin D receptors on NKT cells and ameliorates liver fibrosis by promoting their activity

ADRB2 serves as a novel biomarker and attenuates alcoholic hepatitis via the SIRT1/PGC-1α/PPARα Pathway: Integration of WGCNA, machine learning and experimental validation

Celecoxib and rofecoxib have different effects on small intestinal ischemia/reperfusion injury in rats

Comparison of enteral prucalopride versus intravenous metoclopramide for feeding intolerance in patients with critical illness: a randomized double-blinded study

Rabeprazole suppressed gastric intestinal metaplasia through activation of GPX4-mediated ferroptosis

Integrated multi-omics analyses discovered that cis-TSG alleviated liver injury via modulating lipid metabolism

Mex3a promoter hypomethylation can be utilized to diagnose HBV-associated hepatocellular carcinoma: a randomized controlled trial

p-hydroxy benzaldehyde attenuates intestinal epithelial barrier dysfunction caused by colitis via activating the HNF-1β/SLC26A3 pathway

Modulation of Notch signaling pathway in activated hepatic stellate cells does not ameliorate the outcome of liver fibrosis in carbon tetrachloride and DDC-feeding models

Flavonoids in natural products for the therapy of liver diseases: progress and future opportunities

Multi-omics reveals the alleviating effect of berberine on ulcerative colitis through modulating the gut microbiome and bile acid metabolism in the gut-liver axis