Frontiers in Pharmacology | Gastrointestinal and Hepatic Pharmacology

Review

Accepted on 09 Apr 2025

Targeting Fibroblast Growth Factor (FGF)-21 : A Promising Strategy for Metabolic Dysfunction-Associated Steatotic Liver Disease Treatment

in Gastrointestinal and Hepatic Pharmacology

Xinyue Cui
Quanhao Sun
Haiqiang Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1510322

Systematic Review

Accepted on 08 Apr 2025

The efficacy of aminosalicylates in acute radiation enteritis：a systematic review and meta-analysis

in Gastrointestinal and Hepatic Pharmacology

Zhendong Wu
Chuyan Ni
Zhen Ye
Zhongsheng Xia
Li Li
Zhong Yu
Song Tang
Ying Lin
Wa Zhong

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1544981

Review

Published on 08 Apr 2025

Endogenous micropeptides as potential diagnostic biomarkers and therapeutic drugs

in Gastrointestinal and Hepatic Pharmacology

Aixi Zhong
Shuai Li
Jingxuan Zhang
Jingyuan Zhao
Chenhui Yao

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1545575

151 views

Original Research

Accepted on 07 Apr 2025

Sodium Aescinate Promotes Apoptosis of Pancreatic Stellate Cells and Alleviates Pancreatic Fibrosis by Inhibiting the PI3K/Akt/FOXO1 Signaling Pathways

in Gastrointestinal and Hepatic Pharmacology

Qing-Yun Wang
Bai-Yan Xu
Yi Wang
Yan-Mei Lin
Lin-Fu Zheng
Gang Liu
Da-Zhou Li
Chuan-Shen Jiang
Wen Wang
Xiang-Peng Zeng

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1554260

Original Research

Accepted on 07 Apr 2025

Resveratrol targeting MDM2/P53/PUMA axis to inhibit colonocyte apoptosis in DSS-induced ulcerative colitis mice

in Gastrointestinal and Hepatic Pharmacology

Rui Tang
Quan Ji
Pengyuan Kang
Ling Jiang
Yuan Liu
Pengyu Miao
Xiaofan Xu
Mingxi Tang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1572906

Systematic Review

Accepted on 07 Apr 2025

Assessing the Therapeutic Potential of Rutin in Alleviating Symptoms of Inflammatory Bowel Disease: A Meta-Analysis

in Gastrointestinal and Hepatic Pharmacology

Ruicheng Yan
Zhenkai Zou
Fanglian Zhang
Zhigang Pan
Jinyao Xu
Xuanyi Li
Xiangjun Sun
Xufeng Wang
Feng Qin
Abulikemu Abulizi

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1539469

Review

Published on 07 Apr 2025

Dual signaling pathways of TGF-β superfamily cytokines in hepatocytes: balancing liver homeostasis and disease progression

in Gastrointestinal and Hepatic Pharmacology

Roohi Chaudhary
Ralf Weiskirchen
Marcelo Ehrlich
Yoav I. Henis

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1580500

167 views

Original Research

Published on 07 Apr 2025

Alteration of salivary Streptococcus is associated with statin therapy in older adults: a cohort study

in Gastrointestinal and Hepatic Pharmacology

Daisuke Hisamatsu
Yusuke Ogata
Wataru Suda
Yo Mabuchi
Yuna Naraoka
Taku Yamato
Akimi Ikeba
Kyoko Kumagai
Masahira Hattori
Chihiro Akazawa

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1455753

181 views

Original Research

Published on 07 Apr 2025

Citral protects against metabolic endotoxemia, and systemic disorders caused by high-fat diet-induced obesity via intestinal modulation

in Gastrointestinal and Hepatic Pharmacology

Maycon Tavares Emílio-Silva
Vinicius Peixoto Rodrigues
Mariana Moraes Fioravanti
Antonio Jesús Ruiz-Malagon
Matheus Naia Fioretto
Priscila Romano Raimundo
Rie Ohara
Renata Assunção
Gabriela Bueno
Felipe Lima Dario

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1567217

330 views

Original Research

Published on 04 Apr 2025

Suppressed intestinal secondary bile acids in moxifloxacin-induced hyperglycemia: studies in normal and diabetic GK rats

in Gastrointestinal and Hepatic Pharmacology

Yewen Sun
Yuchen Qu
Zhuan Yang
Bo Lv
Guanjun Wang
Kai Fan
Yuyuan Wang
Jie Pan
Ziyan Du
Yunli Yu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1569856

183 views

Original Research

Published on 04 Apr 2025

MiR-3613-5p targets AQP4 to promote the progression of chronic atrophic gastritis to gastric cancer

in Gastrointestinal and Hepatic Pharmacology

Jian Bi
Yufen Wang
Yingde Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1523689

198 views

Original Research

Published on 04 Apr 2025

Alpha-estradiol and (R)-(−)-ibuprofen inhibit gastric cancer progression via GLI1 G-quadruplex

in Gastrointestinal and Hepatic Pharmacology

Qiang Li
Pan Pan
Qingqing Xian
Jingtan Li
Jingting Wang
Jiaying Cai
Jing Wang
Yanfei Jia
Haiji Sun
Lulu Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1492694

171 views

Review

Accepted on 03 Apr 2025

Understanding the Complex Role of Exosomes in Intestinal Ischemia-Reperfusion Injury: From Pathogenesis to Protection

in Gastrointestinal and Hepatic Pharmacology

Qin Ye
Zi-Hang Yu
Liang Nie
Feixiang Wang
Guo Mu
Bin Lu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1533628

Original Research

Published on 03 Apr 2025

Paricalcitol alleviates intestinal ischemia-reperfusion injury via inhibition of the ATF4-CHOP pathway

in Gastrointestinal and Hepatic Pharmacology

Jiawei Zhang
Tingting Liu
Tongqing Xue
Zhongzhi Jia

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1529343

153 views

Brief Research Report

Published on 02 Apr 2025

Andrographis paniculata restores gut health by suppressing inflammation and strengthening mucosal immunity

in Gastrointestinal and Hepatic Pharmacology

Vidushi Tyagi
Ashish Kumar
Karuna Shanker
Anirban Pal

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1536683

247 views

Systematic Review

Published on 01 Apr 2025

Inflammatory bowel disease therapeutics: a bibliometric analysis of tofacitinib research in ulcerative colitis

in Gastrointestinal and Hepatic Pharmacology

Jianping Zhou
Yuting Xi
Yaping Zhang
Rui Zhang
Hao Fu
Ce Zhou

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1570238

261 views