Frontiers in Pharmacology | Gastrointestinal and Hepatic Pharmacology

Review

Accepted on 19 Feb 2025

Recent advancement in prevention against hepatotoxicity, molecular mechanisms, and bioavailability of gallic acid, a natural phenolic compound: challenges and perspectives

in Gastrointestinal and Hepatic Pharmacology

Chen Peng
zou fan zhao
liu wei

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1549526

Correction

Published on 19 Feb 2025

Corrigendum: Alcohol abstinence rescues hepatic steatosis and liver injury via improving metabolic reprogramming in chronic alcohol-fed mice

in Gastrointestinal and Hepatic Pharmacology

Aiwen Pi
Kai Jiang
Qinchao Ding
Shanglei Lai
Wenwen Yang
Jinyan Zhu
Rui Guo
Yibin Fan
Linfeng Chi
Songtao Li

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1554390

114 views

Original Research

Accepted on 18 Feb 2025

The Protective Role of Cannabidiol in Stress-Induced Liver Injury: Modulating Oxidative Stress and Mitochondrial Damage

in Gastrointestinal and Hepatic Pharmacology

Chengyu Huang
Huichao Liang
Xiaohua Liang
Yueyi Liu
Jiaoling Wang
Haoran Jiang
Xinhui Kou
Jun Chen
Lili Huang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1567210

Original Research

Published on 18 Feb 2025

The median effective dose of ciprofol combined with a low-dose sufentanil for gastroscopy in obese or nonobese patients: a dose-finding study using Dixon’s up-and-down method

in Gastrointestinal and Hepatic Pharmacology

Jie Zhao
Yixiao Zhang
Guowei Su
Shaoyi Wang
Xiaolin Zhang
Guoxiang Wang
Gang Chen

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1521715

136 views

Original Research

Accepted on 17 Feb 2025

Reversed role of CD36 deficiency in high-fat diet or methionine/choline-deficient diet-induced hepatic steatosis and steatohepatitis

in Gastrointestinal and Hepatic Pharmacology

Wenya Zhu
Jialing Ma
Tingting Zhang
Mengmeng Zhu
Yajun Duan
Xiaoxiao Yang
Yuanli Chen

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1522177

Original Research

Accepted on 10 Feb 2025

The association between the gut microbiome and antituberculosis drug-induced liver injury

in Gastrointestinal and Hepatic Pharmacology

Shengfei Pei
Li Yang
Huixia Gao
Yuzhen Liu
Jianhua Lu
Erhei Dai
Chunyan Meng
Fumin Feng
Yuling Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1512815

Original Research

Published on 04 Feb 2025

Effects of celastrol on the heart and liver galaninergic system expression in a mouse model of Western-type diet-induced obesity and metabolic dysfunction-associated steatotic liver disease and steatohepatitis

in Gastrointestinal and Hepatic Pharmacology

Nikolina Canová
Jana Šípková
Mahak Arora
Zuzana Pavlíková
Tomáš Kučera
Ondřej Šeda
Tijana Šopin
Tomáš Vacík
Ondřej Slanař

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1476994

409 views

Review

Accepted on 03 Feb 2025

The potential of Sijunzi decoction in the fight against gastrointestinal disorders: A review

in Gastrointestinal and Hepatic Pharmacology

Liangjun Yang
Zheng Fang
Jiajie Zhu
Xiaofang Li
Bo Yang
Haiyan Liu
Feiyan Lou

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1464498

Original Research

Published on 03 Feb 2025

Rutaecarpine alleviates hepatic ischemia‒reperfusion injury in liver transplantation by inhibiting inflammatory response and oxidative stress

in Gastrointestinal and Hepatic Pharmacology

Yan Liu
Feng Qi
Lun-Jian Xiang
Zhu-Jun Yi
Sheng-Wei Li

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1539744

316 views

Original Research

Published on 03 Feb 2025

Conditional knockdown of hepatic PCSK9 ameliorates high-fat diet-induced liver inflammation in mice

in Gastrointestinal and Hepatic Pharmacology

Xue-Ying Zhang
Qing-Qing Lu
Yan-Jie Li
Shan-Rui Shi
Chao-Nan Ma
Miao Miao
Shou-Dong Guo

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1528250

354 views

Original Research

Published on 31 Jan 2025

Epigallocatechin-3-gallate inhibits the collagen accumulation of oral submucous fibrosis induced by arecoline

in Gastrointestinal and Hepatic Pharmacology

Ge Gao
Caipeng Lin
Ruibo Li
Xi Xie
Hai-Bin Luo

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1540559

226 views

Correction

Published on 28 Jan 2025

Corrigendum: Empagliflozin alleviates hepatic steatosis by activating the AMPK-TET2-autophagy pathway in vivo and in vitro

in Gastrointestinal and Hepatic Pharmacology

Ting Li
Ting Fang
Linxin Xu
Xiangyang Liu
Xiaoyu Li
Mei Xue
Xiaochen Yu
Bei Sun
Liming Chen

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1478437

338 views

Perspective

Accepted on 27 Jan 2025

Combining mechanistic modeling with machine learning as a strategy to predict inflammatory bowel disease clinical scores

in Gastrointestinal and Hepatic Pharmacology

Jaehee V Shim
Piet Van Der Graaf
Douglas W Chung

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1479666

Original Research

Published on 24 Jan 2025

Adverse events of hepatic anti-fibrotic agents in phase 3 and above clinical trials: a descriptive analysis of the WHO-VigiAccess database

in Gastrointestinal and Hepatic Pharmacology

Yuwei Liu
Xu Zhao
Xinrui Wang
Qiang Zhou

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1534628

667 views

Review

Published on 24 Jan 2025

Recent advances in polymeric nanoparticles for the treatment of hepatic diseases

in Gastrointestinal and Hepatic Pharmacology

Feng Gao
Xuefei Feng
Xinyu Li

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1528752

536 views

Review

Published on 23 Jan 2025

Regulation of Hippo-YAP1/TAZ pathway in metabolic dysfunction-associated steatotic liver disease

in Gastrointestinal and Hepatic Pharmacology

Wei Xuan
Dandan Song
Jianghua Hou
Xiuping Meng

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1505117

675 views

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Articles

Recent advancement in prevention against hepatotoxicity, molecular mechanisms, and bioavailability of gallic acid, a natural phenolic compound: challenges and perspectives

Corrigendum: Alcohol abstinence rescues hepatic steatosis and liver injury via improving metabolic reprogramming in chronic alcohol-fed mice

The Protective Role of Cannabidiol in Stress-Induced Liver Injury: Modulating Oxidative Stress and Mitochondrial Damage

The median effective dose of ciprofol combined with a low-dose sufentanil for gastroscopy in obese or nonobese patients: a dose-finding study using Dixon’s up-and-down method

Reversed role of CD36 deficiency in high-fat diet or methionine/choline-deficient diet-induced hepatic steatosis and steatohepatitis

The association between the gut microbiome and antituberculosis drug-induced liver injury

Effects of celastrol on the heart and liver galaninergic system expression in a mouse model of Western-type diet-induced obesity and metabolic dysfunction-associated steatotic liver disease and steatohepatitis

The potential of Sijunzi decoction in the fight against gastrointestinal disorders: A review

Rutaecarpine alleviates hepatic ischemia‒reperfusion injury in liver transplantation by inhibiting inflammatory response and oxidative stress

Conditional knockdown of hepatic PCSK9 ameliorates high-fat diet-induced liver inflammation in mice

Epigallocatechin-3-gallate inhibits the collagen accumulation of oral submucous fibrosis induced by arecoline

Corrigendum: Empagliflozin alleviates hepatic steatosis by activating the AMPK-TET2-autophagy pathway in vivo and in vitro

Combining mechanistic modeling with machine learning as a strategy to predict inflammatory bowel disease clinical scores

Adverse events of hepatic anti-fibrotic agents in phase 3 and above clinical trials: a descriptive analysis of the WHO-VigiAccess database

Recent advances in polymeric nanoparticles for the treatment of hepatic diseases

Regulation of Hippo-YAP1/TAZ pathway in metabolic dysfunction-associated steatotic liver disease