Original Research

Published on 11 Aug 2023

Development of a membrane-based Gi-CASE biosensor assay for profiling compounds at cannabinoid receptors

in Experimental Pharmacology and Drug Discovery

Morgan Scott-Dennis
Fikri A. Rafani
Yicheng Yi
Themiya Perera
Clare R. Harwood
Wolfgang Guba
Arne C. Rufer
Uwe Grether
Dmitry B. Veprintsev
David A. Sykes

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1158091

3,614 views
2 citations

Original Research

Published on 11 Aug 2023

LC-MS-based metabolomics reveals the mechanism of anti-gouty arthritis effect of Wuwei Shexiang pill

in Experimental Pharmacology and Drug Discovery

Jirui Lang
Li Li
Yunyun Quan
Ruirong Tan
Jinbiao Zhao
Min Li
Jin Zeng
Shilong Chen
Ting Wang
Yong Li

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1213602

2,986 views
5 citations

Original Research

Published on 10 Aug 2023

Protective effects of Scutellariae Radix Carbonisata-derived carbon dots on blood-heat and hemorrhage rats

in Experimental Pharmacology and Drug Discovery

Meiling Zhang
Jinjun Cheng
Juan Luo
Changxiang Li
Tingting Hou
Yan Zhao
Yaoxian Wang
Huihua Qu
Hui Kong

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1118550

1,839 views
2 citations

Original Research

Published on 09 Aug 2023

Derivatives of 9-phosphorylated acridine as butyrylcholinesterase inhibitors with antioxidant activity and the ability to inhibit β-amyloid self-aggregation: potential therapeutic agents for Alzheimer’s disease

in Experimental Pharmacology and Drug Discovery

Galina F. Makhaeva
Nadezhda V. Kovaleva
Elena V. Rudakova
Natalia P. Boltneva
Sofya V. Lushchekina
Tatiana Yu Astakhova
Elena N. Timokhina
Olga G. Serebryakova
Alexander V. Shchepochkin
Maxim A. Averkov

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1219980

2,657 views
4 citations

Original Research

Published on 08 Aug 2023

Regulation of mitotic clonal expansion and thermogenic pathway are involved in the antiadipogenic effects of cyanidin-3-O-glucoside

in Experimental Pharmacology and Drug Discovery

Maria Sofia Molonia
Federica Lina Salamone
Claudia Muscarà
Gregorio Costa
Grazia Vento
Antonella Saija
Antonio Speciale
Francesco Cimino

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1225586

2,014 views
7 citations

Editorial

Published on 07 Aug 2023

Editorial: Advanced chemical and material tools to enhance the therapeutic effect of drugs

in Experimental Pharmacology and Drug Discovery

Ayesha Ihsan
Mubashar Rehman

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1239882

923 views

Review

Published on 04 Aug 2023

A review of SARS-CoV-2 drug repurposing: databases and machine learning models

in Experimental Pharmacology and Drug Discovery

Marim Elkashlan
Rahaf M. Ahmad
Malak Hajar
Fatma Al Jasmi
Juan Manuel Corchado
Nurul Athirah Nasarudin
Mohd Saberi Mohamad

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1182465

4,549 views
7 citations

Original Research

Published on 04 Aug 2023

Gentiopicroside modulates glucose homeostasis in high-fat-diet and streptozotocin-induced type 2 diabetic mice

in Experimental Pharmacology and Drug Discovery

Xing Wang
Dongmei Long
Xianghong Hu
Nan Guo

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1172360

2,776 views
6 citations

Review

Published on 03 Aug 2023

Cyclodextrin nanoparticles in targeted cancer theranostics

in Experimental Pharmacology and Drug Discovery

Roshnee Bose
Maharsh Jayawant
Rajesh Raut
Jaya Lakkakula
Arpita Roy
Saad Alghamdi
Naeem F. Qusty
Rohit Sharma
Devvret Verma
Mayeen Uddin Khandaker

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1218867

3,799 views
7 citations

Mini Review

Published on 02 Aug 2023

EGFR is a potential dual molecular target for cancer and Alzheimer’s disease

in Experimental Pharmacology and Drug Discovery

Hee-Jeong Choi
Yoo Joo Jeong
Jieun Kim
Hyang-Sook Hoe

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1238639

5,402 views
20 citations

Review

Published on 02 Aug 2023

Regulators of phagocytosis as pharmacologic targets for stroke treatment

in Experimental Pharmacology and Drug Discovery

Jian Cheng
Wei Wang
Yiqing Xia
Yi Li
Jia Jia
Guodong Xiao

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1122527

2,846 views
2 citations

Brief Research Report

Published on 02 Aug 2023

Alleviation of hippocampal necroptosis and neuroinflammation by NecroX-7 treatment after acute seizures

in Experimental Pharmacology and Drug Discovery

Yihyun Roh
Su Bin Lee
Minseo Kim
Mi-Hye Kim
Hee Jung Kim
Kyung-Ok Cho

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1187819

2,355 views
4 citations

Original Research

Published on 01 Aug 2023

A universal lesion detection method based on partially supervised learning

in Experimental Pharmacology and Drug Discovery

Xun Wang
Xin Shi
Xiangyu Meng
Zhiyuan Zhang
Chaogang Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1084155

1,289 views

Correction

Published on 31 Jul 2023

Expression of Concern: A new method for ethical and efficient evidence generation for off-label medication use in oncology (a case study in glioblastoma)

in Experimental Pharmacology and Drug Discovery

Frontiers Editorial Office

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1264737

1,589 views

Original Research

Published on 31 Jul 2023

Oral administration of linoleic acid immediately before glucose load ameliorates postprandial hyperglycemia

in Experimental Pharmacology and Drug Discovery

Yuta Yamamoto
Katsuya Narumi
Naoko Yamagishi
Toshio Nishi
Takao Ito
Ken Iseki
Masaki Kobayashi
Yoshimitsu Kanai

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1197743

3,337 views
4 citations

Original Research

Published on 28 Jul 2023

Telmisartan versus metformin in downregulating myostatin gene expression and enhancing insulin sensitivity in the skeletal muscles of type 2 diabetic rat model

in Experimental Pharmacology and Drug Discovery

Ahmed Abd-Eltawab Tammam
Waleed Y. Rizg
Amy Fakhry Boushra
Maha Alhelf
Mohammed Alissa
Ghada F. Soliman
Ghada Nady Ouais
Khaled M. Hosny
Hala M. Alkhalidi
Ahmed Magdy Elebiary

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1228525

4,213 views
2 citations

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Articles

Development of a membrane-based Gi-CASE biosensor assay for profiling compounds at cannabinoid receptors

LC-MS-based metabolomics reveals the mechanism of anti-gouty arthritis effect of Wuwei Shexiang pill

Protective effects of Scutellariae Radix Carbonisata-derived carbon dots on blood-heat and hemorrhage rats

Derivatives of 9-phosphorylated acridine as butyrylcholinesterase inhibitors with antioxidant activity and the ability to inhibit β-amyloid self-aggregation: potential therapeutic agents for Alzheimer’s disease

Regulation of mitotic clonal expansion and thermogenic pathway are involved in the antiadipogenic effects of cyanidin-3-O-glucoside

Editorial: Advanced chemical and material tools to enhance the therapeutic effect of drugs

A review of SARS-CoV-2 drug repurposing: databases and machine learning models

Gentiopicroside modulates glucose homeostasis in high-fat-diet and streptozotocin-induced type 2 diabetic mice

Cyclodextrin nanoparticles in targeted cancer theranostics

EGFR is a potential dual molecular target for cancer and Alzheimer’s disease

Regulators of phagocytosis as pharmacologic targets for stroke treatment

Alleviation of hippocampal necroptosis and neuroinflammation by NecroX-7 treatment after acute seizures

A universal lesion detection method based on partially supervised learning

Expression of Concern: A new method for ethical and efficient evidence generation for off-label medication use in oncology (a case study in glioblastoma)

Oral administration of linoleic acid immediately before glucose load ameliorates postprandial hyperglycemia

Telmisartan versus metformin in downregulating myostatin gene expression and enhancing insulin sensitivity in the skeletal muscles of type 2 diabetic rat model