Original Research

Published on 31 Oct 2024

A computational assay for identifying millet-derived compounds that antagonize the interaction between bisphenols and estrogen-related receptor gamma

in Experimental Pharmacology and Drug Discovery

Rajesh Kumar Pathak
Jun-Mo Kim

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1435254

249 views

Original Research

Published on 31 Oct 2024

Protective effect of baicalin on oxidative stress injury in retinal ganglion cells through the JAK/STAT signaling pathway in vitro and in vivo

in Experimental Pharmacology and Drug Discovery

Huan Yu
Dan Zhou
Wei Wang
Qingxia Wang
Min Li
Xiaoyun Ma

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1443472

157 views

Review

Published on 31 Oct 2024

Pathogenesis of thoracic ossification of the ligamentum flavum

in Experimental Pharmacology and Drug Discovery

Chi Zhang
Yanan Chang
Li Shu
Zhongqiang Chen

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1496297

136 views

Original Research

Published on 31 Oct 2024

Epileptic seizures induced by pentylenetetrazole kindling accelerate Alzheimer-like neuropathology in 5×FAD mice

in Experimental Pharmacology and Drug Discovery

Yulian Zou
Chengyan Wang
Huang Li
Meihua Zhong
Jin Lin
Yan Hu
Zhou Chen
Chen-Ling Gan

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1500105

232 views

Review

Published on 30 Oct 2024

Targeting ferroptosis: a novel therapeutic strategy for the treatment of retinal diseases

in Experimental Pharmacology and Drug Discovery

Xiao-Dan Hao
Wen-Hua Xu
Xiaoping Zhang
Junqiang Xue

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1489877

222 views

Original Research

Published on 30 Oct 2024

Novel N-phenyl-2-(aniline) benzamide hydrochloride salt development for colon cancer therapy

in Experimental Pharmacology and Drug Discovery

Yan Peng
Ying Peng
Wei Zhang
Siyi Zhang
Huiqian Peng
Zhen Li
Bo Li
Linyi Liu
Linsheng Zhuo
Zhen Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1452904

153 views

Review

Published on 30 Oct 2024

The regulating role of galectin-9 in immune cell populations

in Experimental Pharmacology and Drug Discovery

Zhanqi Cao
Ping Leng
Hanlin Xu
Xiangpeng Li

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1462061

126 views

Original Research

Published on 30 Oct 2024

Structure–function relationship of dynorphin B variants using naturally occurring amino acid substitutions

in Experimental Pharmacology and Drug Discovery

Luca Zangrandi
Barbara Fogli
Anna Mutti
René Staritzbichler
Victoria Most
Peter W. Hildebrand
Regine Heilbronn
Christoph Schwarzer

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1484730

137 views

Original Research

Published on 30 Oct 2024

Identification of novel SARS-CoV-2 3CLpro inhibitors by molecular docking, in vitro assays, molecular dynamics simulations and DFT analyses

in Experimental Pharmacology and Drug Discovery

Keli Zong
Chaochun Wei
Wei Li
Jiajun Ruan
Susu Zhang
Jingjing Li
Xiaojing Liu
Xu Zhao
Ruiyuan Cao
Hong Yan

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1494953

226 views

Original Research

Published on 29 Oct 2024

Anti-inflammatory effects of para-quinone methide derivatives on ulcerative colitis

in Experimental Pharmacology and Drug Discovery

Yue Qiu
Xin Li
Xu Zhang
Xiaotong Wang
Xuekun Wang
Jie Yang
Guoyun Liu

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1474678

263 views

Review

Accepted on 28 Oct 2024

The Role of CYP-sEH Derived Lipid Mediators in Regulating Mitochondrial Biology and Cellular Senescence: Implications for the Aging Heart

in Experimental Pharmacology and Drug Discovery

Ala Yousef
Liye Fang
Mobina Heidari
Joshua Kranrod
John M. Seubert

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1486717

Original Research

Published on 28 Oct 2024

Effects of fermented Arctium lappa L. root by Lactobacillus casei on hyperlipidemic mice

in Experimental Pharmacology and Drug Discovery

MingJu Chen
Yuxiao Wu
Hongxuan Yang
Tianfeng Liu
Tongkun Han
Wangqiang Dai
Junyue Cen
Fan Ouyang
Jingjing Chen
Jianxin Liu

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1447077

359 views

Original Research

Published on 25 Oct 2024

Alisol A inhibits and stabilizes atherosclerotic plaques by protecting vascular endothelial cells

in Experimental Pharmacology and Drug Discovery

Yang Ma
Dingzhong Song
Jie Yuan
Wusi Hao
Jianqiang Xi
Chunping Yuan
Zhihong Cheng

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1493948

166 views

Review

Published on 24 Oct 2024

Recent advances in the structures and bioactivities of benzopyrans derived from marine fungi: a review

in Experimental Pharmacology and Drug Discovery

Yidan Xi
Huannan Wang
Lixiang Sun
Xueyang Ma
Shuncun Zhang
Zhen Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1482316

328 views

Original Research

Published on 24 Oct 2024

Deciphering quinazoline derivatives’ interactions with EGFR: a computational quest for advanced cancer therapy through 3D-QSAR, virtual screening, and MD simulations

in Experimental Pharmacology and Drug Discovery

Sirajudheen Anwar
Jowaher Alanazi
Nafees Ahemad
Shafaq Raza
Tahir Ali Chohan
Hammad Saleem

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1399372

403 views

Methods

Published on 24 Oct 2024

Effect of 5% lidocaine-medicated plaster in preventing chronic postsurgical pain after knee replacement: protocol for a randomized double-blind placebo-controlled trial

in Experimental Pharmacology and Drug Discovery

Junpeng Yuan
Huichan Xu
Jiongjiong Guo
Yan Li
Youjia Yu
Xiaohong Jin

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1486217

2,067 views

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Articles

A computational assay for identifying millet-derived compounds that antagonize the interaction between bisphenols and estrogen-related receptor gamma

Protective effect of baicalin on oxidative stress injury in retinal ganglion cells through the JAK/STAT signaling pathway in vitro and in vivo

Pathogenesis of thoracic ossification of the ligamentum flavum

Epileptic seizures induced by pentylenetetrazole kindling accelerate Alzheimer-like neuropathology in 5×FAD mice

Targeting ferroptosis: a novel therapeutic strategy for the treatment of retinal diseases

Novel N-phenyl-2-(aniline) benzamide hydrochloride salt development for colon cancer therapy

The regulating role of galectin-9 in immune cell populations

Structure–function relationship of dynorphin B variants using naturally occurring amino acid substitutions

Identification of novel SARS-CoV-2 3CLpro inhibitors by molecular docking, in vitro assays, molecular dynamics simulations and DFT analyses

Anti-inflammatory effects of para-quinone methide derivatives on ulcerative colitis

The Role of CYP-sEH Derived Lipid Mediators in Regulating Mitochondrial Biology and Cellular Senescence: Implications for the Aging Heart

Effects of fermented Arctium lappa L. root by Lactobacillus casei on hyperlipidemic mice

Alisol A inhibits and stabilizes atherosclerotic plaques by protecting vascular endothelial cells

Recent advances in the structures and bioactivities of benzopyrans derived from marine fungi: a review

Deciphering quinazoline derivatives’ interactions with EGFR: a computational quest for advanced cancer therapy through 3D-QSAR, virtual screening, and MD simulations

Effect of 5% lidocaine-medicated plaster in preventing chronic postsurgical pain after knee replacement: protocol for a randomized double-blind placebo-controlled trial