Original Research

Published on 05 Jan 2024

Effects of benidipine, paracetamol, and their combination on postoperative and normal tissue pain thresholds

in Experimental Pharmacology and Drug Discovery

Zehra Bedir
Kezban Tuna Ozkaloglu Erdem
Omer Doymus
Halis Suleyman
Bulent Yavuzer
Betul Cicek
Durdu Altuner
Renad Mammadov
Mehmet Yilmaz
Taha Abdulkadir Coban

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1326128

2,002 views

Systematic Review

Published on 04 Jan 2024

Cartilage tissue healing and regeneration based on biocompatible materials: a systematic review and bibliometric analysis from 1993 to 2022

in Experimental Pharmacology and Drug Discovery

Meng-Xuan Yao
Yi-Fan Zhang
Wei Liu
Hai-Cheng Wang
Chuan Ren
Yu-Qin Zhang
Tai-Long Shi
Wei Chen

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1276849

2,399 views

Original Research

Published on 04 Jan 2024

A minimal PBPK model to accelerate preclinical development of drugs against tuberculosis

in Experimental Pharmacology and Drug Discovery

Federico Reali
Anna Fochesato
Chanchala Kaddi
Roberto Visintainer
Shayne Watson
Micha Levi
Véronique Dartois
Karim Azer
Luca Marchetti

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1272091

3,652 views
3 citations

Original Research

Published on 04 Jan 2024

Nanotechnological synergy of mangiferin and curcumin in modulating PI3K/Akt/mTOR pathway: a novel front in ovarian cancer precision therapeutics

in Experimental Pharmacology and Drug Discovery

Hanan M. Alharbi
Taha Alqahtani
Ali H. Alamri
Vinoth Kumarasamy
Vetriselvan Subramaniyan
K. Suresh Babu

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1276209

3,164 views
5 citations

Review

Published on 04 Jan 2024

Current trends and future prospects of drug repositioning in gastrointestinal oncology

in Experimental Pharmacology and Drug Discovery

Nayeralsadat Fatemi
Mina Karimpour
Hoda Bahrami
Mohammad Reza Zali
Vahid Chaleshi
Andrea Riccio
Ehsan Nazemalhosseini-Mojarad
Mehdi Totonchi

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1329244

3,424 views
2 citations

Original Research

Published on 03 Jan 2024

Ameliorative inhibition of sirtuin 6 by imidazole derivative triggers oxidative stress-mediated apoptosis associated with Nrf2/Keap1 signaling in non-small cell lung cancer cell lines

in Experimental Pharmacology and Drug Discovery

Uma Maheswara Rao Dindi
Sameer Al-Ghamdi
Naif Abdurhman Alrudian
Salman Bin Dayel
Abdulwahab Ali Abuderman
Mohammed Saad Alqahtani
Nasraddin Othman Bahakim
Thiyagarajan Ramesh
Ravikumar Vilwanathan

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1335305

1,953 views
2 citations

Original Research

Published on 03 Jan 2024

The protective effect of PL 1-3 on D-galactose-induced aging mice

in Experimental Pharmacology and Drug Discovery

Pengxiao Li
Yazhong Ma
Xiaotong Wang
Xin Li
Xuekun Wang
Jie Yang
Guoyun Liu

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1304801

2,188 views
1 citation

Original Research

Published on 03 Jan 2024

Fraisinib: a calixpyrrole derivative reducing A549 cell-derived NSCLC tumor in vivo acts as a ligand of the glycine-tRNA synthase, a new molecular target in oncology

in Experimental Pharmacology and Drug Discovery

Iméne Ben Toumia
Tiziana Bachetti
Leila Chekir-Ghedira
Aldo Profumo
Marco Ponassi
Alessandro Di Domizio
Alberto Izzotti
Salvatore Sciacca
Caterina Puglisi
Stefano Forte

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1258108

2,873 views

Original Research

Published on 22 Dec 2023

Casuarina glauca branchlets’ extract as a potential treatment for ulcerative colitis: chemical composition, in silico and in vivo studies

in Experimental Pharmacology and Drug Discovery

Maged E. Mohamed
Azza M. El-Shafae
Eman Fikry
Samar S. Elbaramawi
Mahmoud H. Elbatreek
Nora Tawfeek

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1322181

3,578 views

Original Research

Published on 22 Dec 2023

Pharmacokinetics and bioavailability of a new long-acting insulin analog in healthy Chinese volunteers: an open, randomized, single-dose, two-period and two-sequence cross-over study

in Experimental Pharmacology and Drug Discovery

Ke-Guang Chen
Ye-Hui Zhang
Pan-Pan Ye
Xue-Hu Gao
Lin-Lin Song
Hai-Yan Zhou
Qian Li
Fu-Rong Zhao
Jin-Yi Shi
Xin-Mei Yang

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1294810

1,945 views

Original Research

Published on 21 Dec 2023

Cardioprotective effect of Sanguisorba minor against isoprenaline-induced myocardial infarction in rats

in Experimental Pharmacology and Drug Discovery

Azar Hosseini
Atieh Ghorbani
Mohaddeseh Sadat Alavi
Nima Forouhi
Arezoo Rajabian
Samaneh Boroumand-Noughabi
Amirhossein Sahebkar
Ali H. Eid

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1305816

3,100 views
7 citations

Systematic Review

Published on 20 Dec 2023

Efficacy of mirabegron for ureteral stones: a systematic review with meta-analysis of randomized controlled trials

in Experimental Pharmacology and Drug Discovery

Zhenguo Wang
Junpeng Chi
Yuhua Liu
Jitao Wu
Yuanshan Cui
Chenchen Yang

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1326600

1,627 views

Review

Published on 20 Dec 2023

Role of SIRT3 in bone homeostasis and its application in preventing and treating bone diseases

in Experimental Pharmacology and Drug Discovery

Ke Xu
Jing Li
Ruiming Wen
Bo Chang
Yang Cheng
Xuejie Yi

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1248507

2,755 views
1 citation

Original Research

Published on 19 Dec 2023

Oral FXIIa inhibitor KV998086 suppresses FXIIa and single chain FXII mediated kallikrein kinin system activation

in Experimental Pharmacology and Drug Discovery

Allen C. Clermont
Nivetha Murugesan
Hannah J. Edwards
Daniel K. Lee
Natasha P. Bayliss
Edward J. Duckworth
Stephen J. Pethen
Sally L. Hampton
David Gailani
Edward P. Feener

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1287487

3,094 views
3 citations

Original Research

Published on 15 Dec 2023

Quantitative receptor model for responses that are left- or right-shifted versus occupancy (are more or less concentration sensitive): the SABRE approach

in Experimental Pharmacology and Drug Discovery

Peter Buchwald

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1274065

1,259 views
1 citation

Review

Published on 14 Dec 2023

Signaling pathways regulated by natural active ingredients in the fight against exercise fatigue-a review

in Experimental Pharmacology and Drug Discovery

Rongyue Zhao
Ruomeng Wu
Junjie Jin
Ke Ning
Zhuo Wang
Xuejie Yi
Leonid Kapilevich
Jiao Liu

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1269878

3,284 views
2 citations

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Articles

Effects of benidipine, paracetamol, and their combination on postoperative and normal tissue pain thresholds

Cartilage tissue healing and regeneration based on biocompatible materials: a systematic review and bibliometric analysis from 1993 to 2022

A minimal PBPK model to accelerate preclinical development of drugs against tuberculosis

Nanotechnological synergy of mangiferin and curcumin in modulating PI3K/Akt/mTOR pathway: a novel front in ovarian cancer precision therapeutics

Current trends and future prospects of drug repositioning in gastrointestinal oncology

Ameliorative inhibition of sirtuin 6 by imidazole derivative triggers oxidative stress-mediated apoptosis associated with Nrf2/Keap1 signaling in non-small cell lung cancer cell lines

The protective effect of PL 1-3 on D-galactose-induced aging mice

Fraisinib: a calixpyrrole derivative reducing A549 cell-derived NSCLC tumor in vivo acts as a ligand of the glycine-tRNA synthase, a new molecular target in oncology

Casuarina glauca branchlets’ extract as a potential treatment for ulcerative colitis: chemical composition, in silico and in vivo studies

Pharmacokinetics and bioavailability of a new long-acting insulin analog in healthy Chinese volunteers: an open, randomized, single-dose, two-period and two-sequence cross-over study

Cardioprotective effect of Sanguisorba minor against isoprenaline-induced myocardial infarction in rats

Efficacy of mirabegron for ureteral stones: a systematic review with meta-analysis of randomized controlled trials

Role of SIRT3 in bone homeostasis and its application in preventing and treating bone diseases

Oral FXIIa inhibitor KV998086 suppresses FXIIa and single chain FXII mediated kallikrein kinin system activation

Quantitative receptor model for responses that are left- or right-shifted versus occupancy (are more or less concentration sensitive): the SABRE approach

Signaling pathways regulated by natural active ingredients in the fight against exercise fatigue-a review