Review

Published on 16 Feb 2024

Recent advances in drug delivery of celastrol for enhancing efficiency and reducing the toxicity

in Experimental Pharmacology and Drug Discovery

Yuan Sun
Chengen Wang
Xiaoguang Li
Jun Lu
Maolin Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1137289

1,786 views
6 citations

Original Research

Published on 15 Feb 2024

Utilization of nanotechnology and experimental design in the development and optimization of a posaconazole‒calendula oil nanoemulgel for the treatment of mouth disorders

in Experimental Pharmacology and Drug Discovery

Mohammed Alissa
Ahmed Hjazi
Ghadah S. Abusalim
Ghfren S. Aloraini
Suad A. Alghamdi
Nahed S. Alharthi
Waleed Y. Rizg
Khaled M. Hosny
Nada Binmadi

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1347551

2,240 views

Original Research

Published on 15 Feb 2024

Identification of claudin-2 as a promising biomarker for early diagnosis of pre-diabetes

in Experimental Pharmacology and Drug Discovery

Yang Songtao
Li Fangyu
Cao Jie
Yuan Li

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1370708

1,975 views
2 citations

Original Research

Published on 15 Feb 2024

Network pharmacology, molecular simulation, and binding free energy calculation-based investigation of Neosetophomone B revealed key targets for the treatment of cancer

in Experimental Pharmacology and Drug Discovery

Abbas Khan
Yasir Waheed
Shilpa Kuttikrishnan
Kirti S. Prabhu
Tamam El-Elimat
Shahab Uddin
Feras Q. Alali
Abdelali Agouni

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1352907

2,690 views
1 citation

Review

Published on 14 Feb 2024

Combating antimicrobial resistance: the silent war

in Experimental Pharmacology and Drug Discovery

Letao Bo
Haidong Sun
Yi-Dong Li
Jonathan Zhu
John N. D. Wurpel
Hanli Lin
Zhe-Sheng Chen

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1347750

3,986 views
3 citations

Original Research

Published on 13 Feb 2024

Investigation of anti-nociceptive, anti-inflammatory potential and ADMET studies of pure compounds isolated from Isodon rugosus Wall. ex Benth

in Experimental Pharmacology and Drug Discovery

Osama M. Alshehri
Anwar Zeb
Syed Muhammad Mukarram Shah
Mater H. Mahnashi
Saeed Ahmed Asiri
Omaish Alqahtani
Abdul Sadiq
Muhammad Ibrar
Saleh Alshamrani
Muhammad Saeed Jan

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1328128

1,749 views
5 citations

Data Report

Published on 12 Feb 2024

Leniolisib: a novel treatment for activated phosphoinositide-3 kinase delta syndrome

in Experimental Pharmacology and Drug Discovery

Surya K. De

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1337436

2,898 views
1 citation

Original Research

Published on 09 Feb 2024

Knockdown of EIF4G1 in NSCLC induces CXCL8 secretion

in Experimental Pharmacology and Drug Discovery

Ziyang He
Fangyi Li
Xinyi Zhang
Dacheng Gao
Zhiwen Zhang
Rui Xu
Xingguo Cao
Qiyuan Shan
Zhen Ren
Yali Liu

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1346383

1,645 views

Correction

Published on 09 Feb 2024

Corrigendum: Integrated metabolomics and proteomics reveal biomarkers associated with hemodialysis in end-stage kidney disease

in Experimental Pharmacology and Drug Discovery

Weiwei Lin
Fatemeh Mousavi
Benjamin C. Blum
Christian F Heckendorf
Jarrod Moore
Noah Lampl
Mark McComb
Sergei Kotelnikov
Wenqing Yin
Nabil Rabhi

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1376058

1,177 views

Editorial

Published on 08 Feb 2024

Editorial: Augmented neuro-therapy with nanotechnology-based formulations: progress, opportunities and challenges

in Experimental Pharmacology and Drug Discovery

Mithun Singh Rajput
Viral Patel
Nilesh Prakash Nirmal
Dileep Kumar

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1376878

872 views

Review

Published on 07 Feb 2024

Generative artificial intelligence in drug discovery: basic framework, recent advances, challenges, and opportunities

in Experimental Pharmacology and Drug Discovery

Amit Gangwal
Azim Ansari
Iqrar Ahmad
Abul Kalam Azad
Vinoth Kumarasamy
Vetriselvan Subramaniyan
Ling Shing Wong

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1331062

11,427 views
7 citations

Original Research

Published on 07 Feb 2024

Overexpression of CXCL17 increases migration and invasion of A549 lung adenocarcinoma cells

in Experimental Pharmacology and Drug Discovery

Ekin Koni
Irem Congur
Zeynep Tokcaer Keskin

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1306273

1,971 views
1 citation

Original Research

Published on 06 Feb 2024

Integrating fecal metabolomics and intestinal microbiota to study the mechanism of cannabidiol in the treatment of idiopathic pulmonary fibrosis

in Experimental Pharmacology and Drug Discovery

Mengdi Sun
Feiyu Zhang
Fang Lu
Donghua Yu
Yu Wang
Pingping Chen
Shumin Liu

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1358626

2,385 views
1 citation

Review

Published on 06 Feb 2024

Emerging antioxidant therapies in Friedreich’s ataxia

in Experimental Pharmacology and Drug Discovery

Fred Jonathan Edzeamey
Zenouska Ramchunder
Charareh Pourzand
Sara Anjomani Virmouni

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1359618

3,442 views
2 citations

Original Research

Published on 06 Feb 2024

Neuroprotective effects of a novel peptide through the Rho-integrin-Tie2 and PI3K/Akt pathways in experimental autoimmune encephalomyelitis model

in Experimental Pharmacology and Drug Discovery

Wen Zhou
Han Qu
Xiao-Xiao Fu
Miao-Miao Xu
Qiang Li
Yuan Jiang
Shu Han

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1290128

1,551 views

Review

Published on 06 Feb 2024

A review of the mechanisms of abnormal ceramide metabolism in type 2 diabetes mellitus, Alzheimer’s disease, and their co-morbidities

in Experimental Pharmacology and Drug Discovery

Yun Pan
Jieying Li
Panjie Lin
Lihua Wan
Yiqian Qu
Lingyong Cao
Lei Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1348410

3,710 views
1 citation

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Articles

Recent advances in drug delivery of celastrol for enhancing efficiency and reducing the toxicity

Utilization of nanotechnology and experimental design in the development and optimization of a posaconazole‒calendula oil nanoemulgel for the treatment of mouth disorders

Identification of claudin-2 as a promising biomarker for early diagnosis of pre-diabetes

Network pharmacology, molecular simulation, and binding free energy calculation-based investigation of Neosetophomone B revealed key targets for the treatment of cancer

Combating antimicrobial resistance: the silent war

Investigation of anti-nociceptive, anti-inflammatory potential and ADMET studies of pure compounds isolated from Isodon rugosus Wall. ex Benth

Leniolisib: a novel treatment for activated phosphoinositide-3 kinase delta syndrome

Knockdown of EIF4G1 in NSCLC induces CXCL8 secretion

Corrigendum: Integrated metabolomics and proteomics reveal biomarkers associated with hemodialysis in end-stage kidney disease

Editorial: Augmented neuro-therapy with nanotechnology-based formulations: progress, opportunities and challenges

Generative artificial intelligence in drug discovery: basic framework, recent advances, challenges, and opportunities

Overexpression of CXCL17 increases migration and invasion of A549 lung adenocarcinoma cells

Integrating fecal metabolomics and intestinal microbiota to study the mechanism of cannabidiol in the treatment of idiopathic pulmonary fibrosis

Emerging antioxidant therapies in Friedreich’s ataxia

Neuroprotective effects of a novel peptide through the Rho-integrin-Tie2 and PI3K/Akt pathways in experimental autoimmune encephalomyelitis model

A review of the mechanisms of abnormal ceramide metabolism in type 2 diabetes mellitus, Alzheimer’s disease, and their co-morbidities