Original Research

Published on 03 Apr 2024

Discovery of a novel natural compound, vitekwangin B, with ANO1 protein reduction properties and anticancer potential

in Experimental Pharmacology and Drug Discovery

Yohan Seo
Sion Lee
Minuk Kim
Dongguk Kim
Sung Baek Jeong
Raju Das
Armin Sultana
SeonJu Park
Nguyen Xuan Nhiem
Phan Thi Thanh Huong

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1382787

1,732 views

Original Research

Published on 02 Apr 2024

Relationships between trace elements and cognitive and depressive behaviors in sprague dawley and wistar albino rats

in Experimental Pharmacology and Drug Discovery

Melis Yavuz
Ekin Dongel Dayanc
Fatma Merve Antmen
Elif Keskinöz
Esra Altuntaş
Gökçen Dolu
Berkcan Koç
Emre Tunçcan
Damla Şakar
Ufuk Canözer

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1367469

1,568 views
1 citation

Review

Published on 02 Apr 2024

Different therapeutic approaches in melasma: advances and limitations

in Experimental Pharmacology and Drug Discovery

Parisa Ghasemiyeh
Rahil Fazlinejad
Mohammad Reza Kiafar
Shiva Rasekh
Mohammad Mokhtarzadegan
Soliman Mohammadi-Samani

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1337282

8,524 views

Review

Published on 02 Apr 2024

A comprehensive review of the recent advances on predicting drug-target affinity based on deep learning

in Experimental Pharmacology and Drug Discovery

Xin Zeng
Shu-Juan Li
Shuang-Qing Lv
Meng-Liang Wen
Yi Li

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1375522

3,300 views

Review

Published on 28 Mar 2024

Unveiling the impact of CDK8 on tumor progression: mechanisms and therapeutic strategies

in Experimental Pharmacology and Drug Discovery

Xiaomin Yin
Zhilong He
Kun Chen
Kai Ouyang
Changxuan Yang
Jianjun Li
Hailin Tang
Manbo Cai

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1386929

2,539 views
3 citations

Original Research

Published on 28 Mar 2024

Optimizing fluconazole-embedded transfersomal gel for enhanced antifungal activity and compatibility studies

in Experimental Pharmacology and Drug Discovery

Zhiqiang Cheng
Ujjwala Kandekar
Xiaoshi Ma
Vishal Bhabad
Ashlesha Pandit
Liming Liu
Jiping Luo
Neha Munot
Trushal Chorage
Abhinandan Patil

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1353791

2,033 views
1 citation

Original Research

Published on 27 Mar 2024

Phloretic acid requires the insulin/IGF-1 pathway and autophagy to enhance stress resistance and extend the lifespan of Caenorhabditis elegans

in Experimental Pharmacology and Drug Discovery

Bo Li
Li Dong
Wei Meng
Shi-Ying Xiong
Gui-Sheng Wu
Wen-Zhe Ma
Huai-Rong Luo

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1384227

2,285 views
1 citation

Original Research

Published on 26 Mar 2024

Design and synthesis of novel dihydropyridine- and benzylideneimine-based tyrosinase inhibitors

in Experimental Pharmacology and Drug Discovery

Ifraz Ahmad
Warda Parveen
Shah Noor
Zahoor Udin
Amjad Ali
Ijaz Ali
Riaz Ullah
Hamid Ali

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1332184

1,883 views
2 citations

Original Research

Published on 26 Mar 2024

Pharmacological enhancement of cholinergic neurotransmission alleviates neuroinflammation and improves functional outcomes in a triple transgenic mouse model of Alzheimer’s disease

in Experimental Pharmacology and Drug Discovery

Antonio Munafò
Anna Flavia Cantone
Giulia Di Benedetto
Sebastiano Alfio Torrisi
Chiara Burgaletto
Carlo Maria Bellanca
Gabriella Gaudio
Giuseppe Broggi
Rosario Caltabiano
Gian Marco Leggio

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1386224

1,741 views
1 citation

Original Research

Published on 26 Mar 2024

Dosing optimization of rituximab for primary membranous nephropathy by population pharmacokinetic and pharmacodynamic study

in Experimental Pharmacology and Drug Discovery

Hao Liang
Zhenling Deng
Shu Niu
Weijie Kong
Yang Liu
Song Wang
Haiyan Li
Yue Wang
Danxia Zheng
Dongyang Liu

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1197651

1,754 views
1 citation

Original Research

Published on 25 Mar 2024

Ocular pharmacological and biochemical profiles of 6-thioguanine: a drug repurposing study

in Experimental Pharmacology and Drug Discovery

Maria Consiglia Trotta
Carlo Gesualdo
Caterina Claudia Lepre
Marina Russo
Franca Ferraraccio
Iacopo Panarese
Ernesto Marano
Paolo Grieco
Francesco Petrillo
Anca Hermenean

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1375805

1,394 views

Review

Published on 22 Mar 2024

Clinical research progress of ridaforolimus (AP23573, MK8668) over the past decade: a systemic review

in Experimental Pharmacology and Drug Discovery

Lumin Wang
Qining Qiu
Dawei Yang
Chang Cao
Yanqin Lu
Yulan Zeng
Weiwen Jiang
Yun Shen
Yanrong Ye

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1173240

1,373 views

Original Research

Published on 21 Mar 2024

Pharmacological inhibition of Src family kinases attenuates hyperuricemic nephropathy

in Experimental Pharmacology and Drug Discovery

Chongxiang Xiong
Jin Deng
Xin Wang
Qidi Hou
Shougang Zhuang

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1352730

1,100 views
1 citation

Original Research

Published on 21 Mar 2024

Low TGF-β1 plasma levels are associated with cognitive decline in Down syndrome

in Experimental Pharmacology and Drug Discovery

Margherita Grasso
Annamaria Fidilio
Francesca L’Episcopo
Marilena Recupero
Concetta Barone
Maria Giulia Bacalini
Cristina Benatti
Maria Concetta Giambirtone
Giuseppe Caruso
Donatella Greco

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1379965

1,464 views

Mini Review

Published on 21 Mar 2024

Aberrant tumor vasculature. Facts and pitfalls

in Experimental Pharmacology and Drug Discovery

Domenico Ribatti

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1384721

959 views
1 citation

Original Research

Published on 20 Mar 2024

Mitochondrial energy metabolism-related gene signature as a prognostic indicator for pancreatic adenocarcinoma

in Experimental Pharmacology and Drug Discovery

Yu Ma
Ronghao Tang
Peilin Huang
Danhua Li
Meijian Liao
Shoucui Gao

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1332042

2,086 views
1 citation

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Articles

Discovery of a novel natural compound, vitekwangin B, with ANO1 protein reduction properties and anticancer potential

Relationships between trace elements and cognitive and depressive behaviors in sprague dawley and wistar albino rats

Different therapeutic approaches in melasma: advances and limitations

A comprehensive review of the recent advances on predicting drug-target affinity based on deep learning

Unveiling the impact of CDK8 on tumor progression: mechanisms and therapeutic strategies

Optimizing fluconazole-embedded transfersomal gel for enhanced antifungal activity and compatibility studies

Phloretic acid requires the insulin/IGF-1 pathway and autophagy to enhance stress resistance and extend the lifespan of Caenorhabditis elegans

Design and synthesis of novel dihydropyridine- and benzylideneimine-based tyrosinase inhibitors

Pharmacological enhancement of cholinergic neurotransmission alleviates neuroinflammation and improves functional outcomes in a triple transgenic mouse model of Alzheimer’s disease

Dosing optimization of rituximab for primary membranous nephropathy by population pharmacokinetic and pharmacodynamic study

Ocular pharmacological and biochemical profiles of 6-thioguanine: a drug repurposing study

Clinical research progress of ridaforolimus (AP23573, MK8668) over the past decade: a systemic review

Pharmacological inhibition of Src family kinases attenuates hyperuricemic nephropathy

Low TGF-β1 plasma levels are associated with cognitive decline in Down syndrome

Aberrant tumor vasculature. Facts and pitfalls

Mitochondrial energy metabolism-related gene signature as a prognostic indicator for pancreatic adenocarcinoma