Original Research

Published on 09 May 2024

Label-free detection of prostaglandin transporter (SLCO2A1) function and inhibition: insights by wound healing and TRACT assays

in Experimental Pharmacology and Drug Discovery

Tamara A. M. Mocking
Wieke M. van Oostveen
Jacobus P. D. van Veldhoven
Hugo Minnee
Cynthia M. Fehres
Charles E. Whitehurst
Adriaan P. IJzerman
Laura H. Heitman

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1372109

872 views

Original Research

Published on 09 May 2024

Protective effect of cinnamon extract against cobalt-induced multiple organ damage in rats

in Experimental Pharmacology and Drug Discovery

Bahar Isik
Bahadir Suleyman
Renad Mammadov
Seval Bulut
Bulent Yavuzer
Durdu Altuner
Taha Abdulkadir Coban
Halis Suleyman

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1384181

1,051 views

Original Research

Published on 07 May 2024

Experimental and computational study on anti-gastric cancer activity and mechanism of evodiamine derivatives

in Experimental Pharmacology and Drug Discovery

Jingli Liu
Yingying Xue
Kaidi Bai
Fei Yan
Xu Long
Hui Guo
Hao Yan
Guozheng Huang
Jing Zhou
Yuping Tang

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1380304

1,035 views

Original Research

Published on 02 May 2024

The influence of the way of regression on the results obtained by the receptorial responsiveness method (RRM), a procedure to estimate a change in the concentration of a pharmacological agonist near the receptor

in Experimental Pharmacology and Drug Discovery

Ignac Ovari
Gabor Viczjan
Tamas Erdei
Barbara Takacs
Vera Tarjanyi
Judit Zsuga
Miklos Szucs
Zoltan Szilvassy
Bela Juhasz
Rudolf Gesztelyi

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1375955

547 views

Original Research

Published on 02 May 2024

Deciphering the functional role of clinical mutations in ABCB1, ABCC1, and ABCG2 ABC transporters in endometrial cancer

in Experimental Pharmacology and Drug Discovery

Aayushi Gupta
Manu Smriti Singh
Bipin Singh

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1380371

1,678 views
1 citation

Original Research

Published on 02 May 2024

The association between ondansetron use and mortality risk of traumatic brain injury patients: a population-based study

in Experimental Pharmacology and Drug Discovery

Ruoran Wang
Jing Zhang
Jianguo Xu
Min He

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1362309

1,338 views

Original Research

Published on 01 May 2024

Development and therapeutic evaluation of 5D3(CC-MLN8237)3.2 antibody-theranostic conjugates for PSMA-positive prostate cancer therapy

in Experimental Pharmacology and Drug Discovery

Ioanna Liatsou
Betelhem Assefa
Wathsala Liyanage
Sharmane Surasinghe
Zora Nováková
Cyril Bařinka
Kathleen Gabrielson
Venu Raman
Dmitri Artemov
Sudath Hapuarachchige

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1385598

1,748 views

Original Research

Published on 01 May 2024

Artemisinic acid attenuates osteoclast formation and titanium particle-induced osteolysis via inhibition of RANKL-induced ROS accumulation and MAPK and NF-κB signaling pathways

in Experimental Pharmacology and Drug Discovery

Tian Gao
Chaohong Yu
Xiaofeng Shi
Yuehao Hu
Yongyun Chang
Jingwei Zhang
Yitian Wang
Zanjing Zhai
Xinlin Jia
Yuanqing Mao

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1345380

1,597 views

Original Research

Published on 01 May 2024

Marine-derived EGFR inhibitors: novel compounds targeting breast cancer growth and drug resistance

in Experimental Pharmacology and Drug Discovery

Qi Li
Bo Li
Qian Wang
Chengen Wang
Miao Yu
Tianfu Xu

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1396605

1,121 views
1 citation

Mini Review

Published on 30 Apr 2024

Past and future of an IMI-PharmaTrain (IMI-PhT)-initiated multinational pharmaceutical medicine course at the Semmelweis University in Hungary

in Experimental Pharmacology and Drug Discovery

S. Kerpel-Fronius
M. Gottwald
P. Arányi
G. Renczes
A. Görbe
R. Papp
P. Ferdinandy

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1394987

864 views

Review

Published on 26 Apr 2024

Ferroptosis targeting natural compounds as a promising approach for developing potent liver cancer agents

in Experimental Pharmacology and Drug Discovery

Pratibha Pandey
Deena Elsori
Rahul Kumar
Sorabh Lakhanpal
Indra Rautela
Tariq Mohammed Alqahtani
Fuzail Ahmad
Danish Iqbal
Fahad Khan

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1399677

2,588 views
1 citation

Original Research

Published on 24 Apr 2024

A rapid and simple non-radioactive assay for measuring uptake by solute carrier transporters

in Experimental Pharmacology and Drug Discovery

Kunling Song
Longbin Zhang
Xian Fu
Linfeng Li
Gaolin Zhu
Mingjun Wu
Wei Zhang
Jia He
Sanyong Zhu
Yongjun Dang

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1355507

1,479 views

Original Research

Published on 22 Apr 2024

Design, synthesis, molecular docking, and molecular dynamic studies of novel quinazoline derivatives as phosphodiesterase 7 inhibitors

in Experimental Pharmacology and Drug Discovery

Afaf A. El-Malah
Magdy M. Gineinah
Maan T. Khayat
Anfal S. Aljahdali
Marwa M. Safar
Hadeel A. Almazmumi
Roaa M. Khinkar

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1389076

1,523 views

Original Research

Published on 19 Apr 2024

Effect of curcumin nanoparticles on proliferation and migration of mouse airway smooth muscle cells and airway inflammatory infiltration

in Experimental Pharmacology and Drug Discovery

Yucong Ma
Suping Ye
Kunpeng Sun
Yue Gu

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1344333

1,069 views
3 citations

Original Research

Published on 19 Apr 2024

Da-Cheng-Qi decoction improves severe acute pancreatitis capillary leakage syndrome by regulating tight junction-associated proteins

in Experimental Pharmacology and Drug Discovery

Jiamin Tu
Yinping Jiang
Lei Tu
Yafeng Chen
Liyun Pan
Xinjuan Fan
Jiyun Tian
Jianguo Li
Xinji Wang
Honghao Fu

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1138251

1,088 views
2 citations

Review

Published on 17 Apr 2024

Chinese medicine in the treatment of non-alcoholic fatty liver disease based on network pharmacology: a review

in Experimental Pharmacology and Drug Discovery

Shihao Zheng
Chengyuan Xue
Size Li
Xiaobin Zao
Xiaoke Li
Qiyao Liu
Xu Cao
Wei Wang
Wenying Qi
Peng Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1381712

3,491 views
2 citations

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Articles

Label-free detection of prostaglandin transporter (SLCO2A1) function and inhibition: insights by wound healing and TRACT assays

Protective effect of cinnamon extract against cobalt-induced multiple organ damage in rats

Experimental and computational study on anti-gastric cancer activity and mechanism of evodiamine derivatives

The influence of the way of regression on the results obtained by the receptorial responsiveness method (RRM), a procedure to estimate a change in the concentration of a pharmacological agonist near the receptor

Deciphering the functional role of clinical mutations in ABCB1, ABCC1, and ABCG2 ABC transporters in endometrial cancer

The association between ondansetron use and mortality risk of traumatic brain injury patients: a population-based study

Development and therapeutic evaluation of 5D3(CC-MLN8237)3.2 antibody-theranostic conjugates for PSMA-positive prostate cancer therapy

Artemisinic acid attenuates osteoclast formation and titanium particle-induced osteolysis via inhibition of RANKL-induced ROS accumulation and MAPK and NF-κB signaling pathways

Marine-derived EGFR inhibitors: novel compounds targeting breast cancer growth and drug resistance

Past and future of an IMI-PharmaTrain (IMI-PhT)-initiated multinational pharmaceutical medicine course at the Semmelweis University in Hungary

Ferroptosis targeting natural compounds as a promising approach for developing potent liver cancer agents

A rapid and simple non-radioactive assay for measuring uptake by solute carrier transporters

Design, synthesis, molecular docking, and molecular dynamic studies of novel quinazoline derivatives as phosphodiesterase 7 inhibitors

Effect of curcumin nanoparticles on proliferation and migration of mouse airway smooth muscle cells and airway inflammatory infiltration

Da-Cheng-Qi decoction improves severe acute pancreatitis capillary leakage syndrome by regulating tight junction-associated proteins

Chinese medicine in the treatment of non-alcoholic fatty liver disease based on network pharmacology: a review