Frontiers in Pharmacology | Experimental Pharmacology and Drug Discovery

Original Research

Published on 03 Dec 2024

Combining Acmella oleracea and Boswellia serrata extracts: a novel pharmacological approach in inflammatory vestibulodynia

in Experimental Pharmacology and Drug Discovery

Antimo Fusco
Michela Perrone
Federica Ricciardi
Andrea Maria Morace
Roozbe Bonsale
Milena Melake Teweldemedhin
Emanuele Di Martino
Rebecca Limongelli
Alfonso Papa
Sabatino Maione

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1508107

1,249 views
1 citation

Original Research

Published on 03 Dec 2024

In vitro hair growth-promoting effects of araliadiol via the p38/PPAR-γ signaling pathway in human hair follicle stem cells and dermal papilla cells

in Experimental Pharmacology and Drug Discovery

Seokmuk Park
Han Woong Park
Dae Bang Seo
Dae Sung Yoo
Seunghee Bae

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1482898

1,806 views

Original Research

Published on 03 Dec 2024

Clinical predictors of treatment response to gabapentin in women with unexplained chronic pelvic pain

in Experimental Pharmacology and Drug Discovery

Lydia Coxon
Maryam Amer
Jane Daniels
Ann M. Doust
Scott C. Mackenzie
Andrew W. Horne
Katy Vincent

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1460206

756 views
1 citation

Original Research

Published on 03 Dec 2024

Coptisine enhances the sensitivity of chemoresistant breast cancer cells by inhibiting the function and expression of ABC transporters

in Experimental Pharmacology and Drug Discovery

Safaa Yehia Eid

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1472458

888 views
2 citations

Correction

Published on 02 Dec 2024

Corrigendum: Estrogens modulate somatostatin receptors expression and synergize with the somatostatin analog pasireotide in prostate cells

in Experimental Pharmacology and Drug Discovery

Valentina Rossi
Erika Di Zazzo
Giovanni Galasso
Caterina De Rosa
Ciro Abbondanza
Antonio A. Sinisi
Lucia Altucci
Antimo Migliaccio
Gabriella Castoria

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1515349

405 views

Original Research

Published on 29 Nov 2024

Discovery of novel PARP1/NRP1 dual-targeting inhibitors with strong antitumor potency

in Experimental Pharmacology and Drug Discovery

Juanjuan Liu
Yifei Geng
Su Jiang
Lixia Guan
Junyi Gao
Miao-Miao Niu
Jindong Li

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1454957

1,002 views

Review

Published on 29 Nov 2024

The role of artificial intelligence in drug screening, drug design, and clinical trials

in Experimental Pharmacology and Drug Discovery

Yuyuan Wu
Lijing Ma
Xinyi Li
Jingpeng Yang
Xinyu Rao
Yiru Hu
Jingyi Xi
Lin Tao
Jianjun Wang
Lailing Du

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1459954

4,414 views
4 citations

Editorial

Published on 29 Nov 2024

Editorial: What does experimental pharmacology and drug discovery look like in 2035?

in Experimental Pharmacology and Drug Discovery

Maria Serena Fabbrini
Riccardo Vago

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1504817

1,292 views

Original Research

Published on 28 Nov 2024

Investigation of the effects of Periplaneta americana (L.) extract on ischemic stroke based on combined multi-omics of gut microbiota

in Experimental Pharmacology and Drug Discovery

Xin Yang
Canhui Hong
Tangfei Guan
ChengGui Zhang
Peiyun Xiao
Yongshou Yang
Huai Xiao
Zhengchun He

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1429960

1,250 views

Original Research

Published on 26 Nov 2024

Cytotoxicity of natural and synthetic cannabinoids and their synergistic antiproliferative effects with cisplatin in human ovarian cancer cells

in Experimental Pharmacology and Drug Discovery

Ying Chen
Huifang Li
Jia Liu
Jie Ni
Qicheng Deng
Haotian He
Panpan Wu
Yinsheng Wan
Navindra P. Seeram
Chang Liu

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1496131

1,330 views
1 citation

Original Research

Published on 25 Nov 2024

Dexmedetomidine regulates the anti-oxidation and autophagy of adipose-derived stromal cells under H2O2-induced oxidative stress through Nrf2/p62 pathway and improves the retention rate of autologous fat transplantation

in Experimental Pharmacology and Drug Discovery

Zihao Li
Qing Wei
Yijun Li
Fangfang Yang
Chen Ke
Tian Li
Liqun Li
Zhongming Cai

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1453938

934 views

Original Research

Published on 25 Nov 2024

Preparation and characterization of Pistacia atlantica oleo-gum-resin-loaded electrospun nanofibers and evaluating its wound healing activity in two rat models of skin scar and burn wound

in Experimental Pharmacology and Drug Discovery

Ghobad Mohammadi
Mosayyeb Safari
Masoud Karimi
Amin Iranpanah
Mohammad Hosein Farzaei
Sajad Fakhri
Javier Echeverría

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1474981

1,415 views
1 citation

Original Research

Published on 21 Nov 2024

Evaluation of the inhibitory mechanism of Pennisetum glaucum (pearl millet) bioactive compounds for rheumatoid arthritis: an in vitro and computational approach

in Experimental Pharmacology and Drug Discovery

Maria Sharif
Peter John
Attya Bhatti
Rehan Zafar Paracha
Abid Majeed

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1488790

1,622 views
1 citation

Original Research

Published on 20 Nov 2024

Exploring somatic mutations in BRAF, KRAS, and NRAS as therapeutic targets in Saudi colorectal cancer patients through massive parallel sequencing and variant classification

in Experimental Pharmacology and Drug Discovery

Thamer Abdulhamid Aljuhani
Noor Ahmad Shaik
Rahaf Talal Alqawas
Rana Y. Bokhary
Mahmood Al-Mutadares
Hadiah Bassam Al Mahdi
Nuha Al-Rayes
Ashraf AbdulRahman El-Harouni
Ramu Elango
Babajan Banaganapalli

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1498295

1,301 views

Systematic Review

Published on 18 Nov 2024

Efficacy and safety of Epimedium total flavonoids for primary osteoporosis: a systematic review and meta-analysis

in Experimental Pharmacology and Drug Discovery

Jinkun Li
Xudong Huang
Yifeng Yuan
Haixin Zhang
Hang Zhou
Wei Xiong
Yuyi Li
Zechen Zhang
Fengqing Qie
Yingdelong Mao

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1505926

1,465 views

Original Research

Published on 18 Nov 2024

Integrated chemical analysis, metabolic profiling, network pharmacology, molecular docking and toxicity prediction to reveal the active ingredients and their safety of raw and prepared rhubarbs in the treatment of gastric ulcers

in Experimental Pharmacology and Drug Discovery

Chenxi Wang
Xin Zhao
Jingjing Jiang
Mengqi Jia
Wenqing Shi
Zhenghua Wu
Shiyu Feng
Guorong Fan
Yuefen Lou

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1481091

1,415 views