Original Research

Published on 23 May 2024

Fragment-based virtual screening identifies novel leads against Plasmepsin IX (PlmIX) of Plasmodium falciparum: Homology modeling, molecular docking, and simulation approaches

in Experimental Pharmacology and Drug Discovery

Haider Thaer Abdulhameed Almuqdadi
Sumaiya Kifayat
Razique Anwer
Jihad Alrehaili
Mohammad Abid

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1387629

1,077 views
1 citation

Original Research

Published on 23 May 2024

Prevention of cyclophosphamide-induced immune suppression by polysaccharides from Apocynum venetum flowers via enhancing immune response, reducing oxidative stress, and regulating gut microbiota in mice

in Experimental Pharmacology and Drug Discovery

Qingchun Zhao
Jinmei Wang
Haiyang Liang
Wenjing Guo
Yanhai Chu
Lijun Liu
Wenyi Kang

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1354794

971 views
1 citation

Review

Published on 23 May 2024

Ferroptosis inhibitors: past, present and future

in Experimental Pharmacology and Drug Discovery

Lei Zhang
Yi Lin Luo
Yang Xiang
Xin Yue Bai
Rong Rong Qiang
Xin Zhang
Yan Ling Yang
Xiao Long Liu

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1407335

3,489 views
3 citations

Original Research

Published on 22 May 2024

System biology approach to identify the novel biomarkers in glioblastoma multiforme tumors by using computational analysis

in Experimental Pharmacology and Drug Discovery

Safar M. Alqahtani
Ali Altharawi
Alhumaidi Alabbas
Faisal Ahmad
Hassan Ayaz
Asia Nawaz
Sidra Rahman
Manal A. Alossaimi

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1364138

2,221 views

Original Research

Published on 21 May 2024

MPASL: multi-perspective learning knowledge graph attention network for synthetic lethality prediction in human cancer

in Experimental Pharmacology and Drug Discovery

Ge Zhang
Yitong Chen
Chaokun Yan
Jianlin Wang
Wenjuan Liang
Junwei Luo
Huimin Luo

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1398231

833 views

Original Research

Published on 21 May 2024

Investigating Sulforaphane’s anti-virulence and anti-quorum sensing properties against Pseudomonas aeruginosa

in Experimental Pharmacology and Drug Discovery

Mahmoud M. Bendary
Mohamed A. M. Ali
Alyaa S. Abdel Halim
Fehmi Boufahja
Anis Ahmad Chaudhary
Amr Elkelish
Rania H. M. Soliman
Wael A. H. Hegazy

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1406653

1,304 views
1 citation

Original Research

Published on 20 May 2024

MASMDDI: multi-layer adaptive soft-mask graph neural network for drug-drug interaction prediction

in Experimental Pharmacology and Drug Discovery

Junpeng Lin
Binsheng Hong
Zhongqi Cai
Ping Lu
Kaibiao Lin

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1369403

774 views

Original Research

Published on 17 May 2024

Benserazide, a cystathionine beta-synthase (CBS) inhibitor, potentially enhances the anticancer effects of paclitaxel via inhibiting the S-sulfhydration of SIRT1 and the HIF1-α/VEGF pathway

in Experimental Pharmacology and Drug Discovery

Wei Zhao
Shasha Feng
Jian Wang
Zhenshuai Zhang
Lu Chen
Li Jiang
Ming Li
Tianxiao Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1404532

1,327 views

Correction

Published on 17 May 2024

Corrigendum: NmFGF1-regulated glucolipid metabolism and angiogenesis improves functional recovery in a mouse model of diabetic stroke and acts via the AMPK signaling pathway

in Experimental Pharmacology and Drug Discovery

Yeli Zhao
Shasha Ye
Jingjing Lin
Fei Liang
Jun Chen
Jian Hu
Kun Chen
Yani Fang
Xiongjian Chen
Ye Xiong

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1392148

480 views

Original Research

Published on 17 May 2024

To elucidate the mechanism of “Scrophulariae Radix–Fritillaria” in goiter by integrated metabolomics and serum pharmaco-chemistry

in Experimental Pharmacology and Drug Discovery

Lixin Chen
Wei Liang
Kun Zhang
Zishuo Wang
Wei Cheng
Wenlan Li

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1206718

963 views
1 citation

Original Research

Published on 17 May 2024

Repeated epidural delivery of Shinbaro2: effects on neural recovery, inflammation, and pain modulation in a rat model of lumbar spinal stenosis

in Experimental Pharmacology and Drug Discovery

Jin Young Hong
Changhwan Yeo
Hyun Kim
Junseon Lee
Wan-Jin Jeon
Yoon Jae Lee
In-Hyuk Ha

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1324251

1,181 views

Original Research

Published on 17 May 2024

GDF-15 is a potential candidate biomarker for an elevated risk of cardiotoxicity in breast cancer patients receiving neoadjuvant dual anti-HER2 therapy

in Experimental Pharmacology and Drug Discovery

Chunyu Tian
Hongxu Zhang
Jianping Liu
Mengze Xu
Lihui Ma

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1396133

1,161 views

Review

Published on 15 May 2024

The mysterious association between adiponectin and endometriosis

in Experimental Pharmacology and Drug Discovery

Yong-Qing Zhao
Yi-Fan Ren
Bing-Bing Li
Chao Wei
Bin Yu

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1396616

1,521 views
2 citations

Original Research

Published on 14 May 2024

Structure-guided design and cloning of peptide inhibitors targeting CDK9/cyclin T1 protein-protein interaction

in Experimental Pharmacology and Drug Discovery

Mohammad Sadegh Taghizadeh
Mohsen Taherishirazi
Ali Niazi
Alireza Afsharifar
Ali Moghadam

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1327820

1,758 views
2 citations

Correction

Published on 13 May 2024

Corrigendum: BM-MSCs alleviate diabetic nephropathy in male rats by regulating ER stress, oxidative stress, inflammation, and apoptotic pathways

in Experimental Pharmacology and Drug Discovery

Tarek Khamis
Adel Abdelkhalek
Hussein Abdellatif
Nourelden Dwidar
Ahmed Said
Rama Ahmed
Kerolos Wagdy
Rowina Elgarhy
Rawan Eltahan
Hisham Mohamed

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1394151

618 views

Systematic Review

Published on 10 May 2024

Knowledge mapping of graph neural networks for drug discovery: a bibliometric and visualized analysis

in Experimental Pharmacology and Drug Discovery

Rufan Yao
Zhenhua Shen
Xinyi Xu
Guixia Ling
Rongwu Xiang
Tingyan Song
Fei Zhai
Yuxuan Zhai

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1393415

2,127 views
1 citation

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Articles

Fragment-based virtual screening identifies novel leads against Plasmepsin IX (PlmIX) of Plasmodium falciparum: Homology modeling, molecular docking, and simulation approaches

Prevention of cyclophosphamide-induced immune suppression by polysaccharides from Apocynum venetum flowers via enhancing immune response, reducing oxidative stress, and regulating gut microbiota in mice

Ferroptosis inhibitors: past, present and future

System biology approach to identify the novel biomarkers in glioblastoma multiforme tumors by using computational analysis

MPASL: multi-perspective learning knowledge graph attention network for synthetic lethality prediction in human cancer

Investigating Sulforaphane’s anti-virulence and anti-quorum sensing properties against Pseudomonas aeruginosa

MASMDDI: multi-layer adaptive soft-mask graph neural network for drug-drug interaction prediction

Benserazide, a cystathionine beta-synthase (CBS) inhibitor, potentially enhances the anticancer effects of paclitaxel via inhibiting the S-sulfhydration of SIRT1 and the HIF1-α/VEGF pathway

Corrigendum: NmFGF1-regulated glucolipid metabolism and angiogenesis improves functional recovery in a mouse model of diabetic stroke and acts via the AMPK signaling pathway

To elucidate the mechanism of “Scrophulariae Radix–Fritillaria” in goiter by integrated metabolomics and serum pharmaco-chemistry

Repeated epidural delivery of Shinbaro2: effects on neural recovery, inflammation, and pain modulation in a rat model of lumbar spinal stenosis

GDF-15 is a potential candidate biomarker for an elevated risk of cardiotoxicity in breast cancer patients receiving neoadjuvant dual anti-HER2 therapy

The mysterious association between adiponectin and endometriosis

Structure-guided design and cloning of peptide inhibitors targeting CDK9/cyclin T1 protein-protein interaction

Corrigendum: BM-MSCs alleviate diabetic nephropathy in male rats by regulating ER stress, oxidative stress, inflammation, and apoptotic pathways

Knowledge mapping of graph neural networks for drug discovery: a bibliometric and visualized analysis