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Original Research

Published on 08 May 2020

Polymorphisms of Drug-Metabolizing Enzymes and Transporters Contribute to the Individual Variations of Erlotinib Steady State Trough Concentration, Treatment Outcomes, and Adverse Reactions in Epidermal Growth Factor Receptor–Mutated Non-Small Cell Lung Cancer Patients

in Drug Metabolism and Transport

  • Dehua Liao
  • Zhigang Liu
  • Yongchang Zhang
  • Ni Liu
  • Dunwu Yao
  • Lizhi Cao
  • Yun Chen
  • Yilan Fu
  • Nong Yang
  • Daxiong Xiang
Polymorphisms of Drug-Metabolizing Enzymes and Transporters Contribute to the Individual Variations of Erlotinib Steady State Trough Concentration, Treatment Outcomes, and Adverse Reactions in Epidermal Growth Factor Receptor–Mutated Non-Small Cell Lung Cancer Patients
Frontiers in Pharmacology
doi 10.3389/fphar.2020.00664
  • 4,910 views
  • 4 citations