Original Research

Published on 07 Aug 2024

Exploring stevioside binding affinity with various proteins and receptors actively involved in the signaling pathway and a future candidate for diabetic patients

in Drug Metabolism and Transport

Salman Khan
Nisar Ahmad
Hina Fazal
Ibrahim A. Saleh
Mostafa A. Abdel-Maksoud
Abdul Malik
Gehad AbdElgayed
Arshad Jalal
Kamran Rauf
Liaqat Ali

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1377916

1,437 views
1 citation

Editorial

Published on 05 Aug 2024

Editorial: Pharmacokinetic-pharmacodynamic model of drugs and their pharmacokinetic differences between normal and disease states

in Drug Metabolism and Transport

Zipeng Gong
Ruixing Chen
Ling Ye
Guo Ma
Yanfang Xian
Kaustubh Kulkarni

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1451176

541 views

Correction

Published on 01 Aug 2024

Corrigendum: Paclitaxel-incorporated nanoparticles improve functional recovery after spinal cord injury

in Drug Metabolism and Transport

Xinzhu Zhang
Wu Xiong
Guang Kong
Yushan Zhen
Qiang Zeng
Siming Wang
Sheng Chen
Jun Gu
Cong Li
Kaijin Guo

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1451951

597 views

Review

Published on 24 Jul 2024

Efflux ABC transporters in drug disposition and their posttranscriptional gene regulation by microRNAs

in Drug Metabolism and Transport

Yimei Wang
Mei-Juan Tu
Ai-Ming Yu

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1423416

1,341 views

Original Research

Published on 22 Jul 2024

A new crystalline daidzein-piperazine salt with enhanced solubility, permeability, and bioavailability

in Drug Metabolism and Transport

Jiacheng Meng
Chenxu Qiu
Chenyue Lu
Xin He
Xinghua Zhao

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1385637

957 views

Original Research

Published on 18 Jul 2024

Metabolic characterization of the new benzimidazole synthetic opioids - nitazenes

in Drug Metabolism and Transport

Gajanan R. Jadhav
Pius S. Fasinu

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1434573

2,087 views

Original Research

Published on 16 Jul 2024

Population pharmacokinetics and exposure–response analyses of SAF-189s in Chinese patients with ALK+/ROS1+ non-small cell lung cancer

in Drug Metabolism and Transport

Yinhui Liu
Yan Tan
Lin Hu
Jinlong Li
Jiansong Yang
Lei Diao
Jin Yang

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1418549

883 views

Original Research

Published on 09 Jul 2024

Advancing drug discovery through assay development: a survey of tool compounds within the human solute carrier superfamily

in Drug Metabolism and Transport

Daniela Digles
Alvaro Ingles-Prieto
Vojtech Dvorak
Tamara A. M. Mocking
Ulrich Goldmann
Andrea Garofoli
Evert J. Homan
Alberto Di Silvio
Lucia Azzollini
Francesca Sassone

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1401599

3,317 views
1 citation

Original Research

Published on 04 Jul 2024

Association of dipeptidyl peptidase-4 inhibitor and recurrent pancreatitis risk among patients with type 2 diabetes: A retrospective cohort study

in Drug Metabolism and Transport

Yi-Sun Yang
Edy Kornelius
Yu-Hsun Wang
Shih-Chan Lo
Chien-Ning Huang

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1341363

817 views

Methods

Published on 26 Jun 2024

Pharmacokinetic profile of phenytoin in dried blood spot with high-performance liquid chromatography—photodiode array

in Drug Metabolism and Transport

Yahdiana Harahap
Limeylia Ng
Sunarsih Sunarsih

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1326996

938 views

Original Research

Published on 21 Jun 2024

Exploring the pharmacokinetics and tolerability of cyclooxygenase inhibitor ampiroxicam: a phase I study on single and multiple oral doses

in Drug Metabolism and Transport

Pengfei Zhao
Ying Qi

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1429971

1,011 views

Original Research

Published on 20 Jun 2024

Systematic studies on the kinetic process of 20(S)-protopanaxadiol in rats and dogs: absorption, distribution, metabolism and excretion

in Drug Metabolism and Transport

Pengfei Li
Min Zhang
Meng Chen
Guangxu Liu
Linghui Meng
Dan Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1430780

742 views

Original Research

Published on 19 Jun 2024

Development of radioiodine-labeled mequitazine for evaluation of hepatic CYP2D activity

in Drug Metabolism and Transport

Asuka Mizutani
Masato Kobayashi
Kodai Nishi
Ken-ichi Fujita
Kotaro Takahashi
Yuka Muranaka
Kakeru Sato
Masanori Kitamura
Chie Suzuki
Ryuichi Nishii

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1397288

688 views

Original Research

Published on 14 Jun 2024

Preclinical pharmacokinetic characterization of amdizalisib, a novel PI3Kδ inhibitor for the treatment of hematological malignancies

in Drug Metabolism and Transport

Shuwen Jiang
Xiangkun Li
Weifang Xue
Sumei Xia
Jian Wang
Yang Sai
Guangxiu Dai
Weiguo Su

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1392209

818 views

Original Research

Published on 12 Jun 2024

A phase I, randomized study to evaluate the safety, tolerability, and pharmacokinetics of mefunidone in healthy subjects

in Drug Metabolism and Transport

Mai Han
Bishan Huo
Gaoyun Hu
Xin Zhang
Gang Cui
Wei Wu
Na Mi
Shixi Zhang
Jiangli Jin
Xing Lu

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1414066

862 views
2 citations

Original Research

Published on 11 Jun 2024

Development and validation of UPLC-MS/MS method for icariin and its metabolites in mouse urine

in Drug Metabolism and Transport

Na Li
Mei Yuan
Jinjing Che

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1389754

629 views

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Articles

Exploring stevioside binding affinity with various proteins and receptors actively involved in the signaling pathway and a future candidate for diabetic patients

Editorial: Pharmacokinetic-pharmacodynamic model of drugs and their pharmacokinetic differences between normal and disease states

Corrigendum: Paclitaxel-incorporated nanoparticles improve functional recovery after spinal cord injury

Efflux ABC transporters in drug disposition and their posttranscriptional gene regulation by microRNAs

A new crystalline daidzein-piperazine salt with enhanced solubility, permeability, and bioavailability

Metabolic characterization of the new benzimidazole synthetic opioids - nitazenes

Population pharmacokinetics and exposure–response analyses of SAF-189s in Chinese patients with ALK+/ROS1+ non-small cell lung cancer

Advancing drug discovery through assay development: a survey of tool compounds within the human solute carrier superfamily

Association of dipeptidyl peptidase-4 inhibitor and recurrent pancreatitis risk among patients with type 2 diabetes: A retrospective cohort study

Pharmacokinetic profile of phenytoin in dried blood spot with high-performance liquid chromatography—photodiode array

Exploring the pharmacokinetics and tolerability of cyclooxygenase inhibitor ampiroxicam: a phase I study on single and multiple oral doses

Systematic studies on the kinetic process of 20(S)-protopanaxadiol in rats and dogs: absorption, distribution, metabolism and excretion

Development of radioiodine-labeled mequitazine for evaluation of hepatic CYP2D activity

Preclinical pharmacokinetic characterization of amdizalisib, a novel PI3Kδ inhibitor for the treatment of hematological malignancies

A phase I, randomized study to evaluate the safety, tolerability, and pharmacokinetics of mefunidone in healthy subjects

Development and validation of UPLC-MS/MS method for icariin and its metabolites in mouse urine