Original Research

Published on 27 Apr 2022

Effect of Baicalein on the Pharmacokinetics of Cilostazol and Its Two Metabolites in Rat Plasma Using UPLC-MS/MS Method

in Drug Metabolism and Transport

Qinghua Weng
Chaojie Chen
Jianhua Xiong
Ya-Nan Liu
Xinxin Pan
Ju Cui
Jian-Ping Cai
Ren-Ai Xu

Frontiers in Pharmacology

doi 10.3389/fphar.2022.888054

2,097 views
2 citations

Original Research

Published on 26 Apr 2022

Compatibility of Fuzi and Ginseng Significantly Increase the Exposure of Aconitines

in Drug Metabolism and Transport

Ze-Yan Chen
Xu-Ya Wei
Zi-Dong Qiu
Yun Huang
Ting Tan
Yu-Lin Feng
Juan Guo
Guang-Hong Cui
Lu-Qi Huang
Chang-Jiang-Sheng Lai

Frontiers in Pharmacology

doi 10.3389/fphar.2022.883898

2,785 views
6 citations

Original Research

Published on 25 Apr 2022

Engineering of Stimulus-Responsive Pirfenidone Liposomes for Pulmonary Delivery During Treatment of Idiopathic Pulmonary Fibrosis

in Drug Metabolism and Transport

Meishan Han
Yingjian Song
Sha Liu
Xiaoyan Lu
Linyu Su
Meixuan Liu
Xiaosu Zhu
Kaoxiang Sun
Yanan Lu
Aiping Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2022.882678

3,928 views
12 citations

Original Research

Published on 20 Apr 2022

Single and Repeated Doses of EGb 761® do not Affect Pharmacokinetics or Pharmacodynamics of Rivaroxaban in Healthy Subjects

in Drug Metabolism and Transport

Robert Hoerr
Andrea Zimmermann
Friedeborg Seitz
Angelika Dienel

Frontiers in Pharmacology

doi 10.3389/fphar.2022.868843

4,798 views
2 citations

Original Research

Published on 20 Apr 2022

Dynamics of Erythroferrone Response to Erythropoietin in Rats

in Drug Metabolism and Transport

Peng Xu
Raymond S. M. Wong
Wojciech Krzyzanski
Xiaoyu Yan

Frontiers in Pharmacology

doi 10.3389/fphar.2022.876573

2,531 views
3 citations

Original Research

Published on 20 Apr 2022

The Unusual Cosubstrate Specificity of NQO2: Conservation Throughout the Amniotes and Implications for Cellular Function

in Drug Metabolism and Transport

Faiza Islam
Kevin K. Leung
Matthew D. Walker
Shahed Al Massri
Brian H. Shilton

Frontiers in Pharmacology

doi 10.3389/fphar.2022.838500

3,215 views
5 citations

Original Research

Published on 13 Apr 2022

Urinary Profile of Endogenous Gamma-Hydroxybutyric Acid and its Biomarker Metabolites in Healthy Korean Females: Determination of Age-Dependent and Intra-Individual Variability and Identification of Metabolites Correlated With Gamma-Hydroxybutyric Acid

in Drug Metabolism and Transport

Suji Kim
Suein Choi
Min Seo Lee
Mingyu Kim
Maria Park
Sungpil Han
Seunghoon Han
Hye Suk Lee
Sooyeun Lee

Frontiers in Pharmacology

doi 10.3389/fphar.2022.853971

2,838 views
4 citations

Original Research

Published on 11 Apr 2022

Dosage Strategy of Linezolid According to the Trough Concentration Target and Renal Function in Chinese Critically Ill Patients

in Drug Metabolism and Transport

Fan Wu
Xiao-Shan Zhang
Ying Dai
Zi-Ye Zhou
Chun-Hong Zhang
Lu Han
Fang-Min Xu
Ye-Xuan Wang
Da-Wei Shi
Guan-Yang Lin

Frontiers in Pharmacology

doi 10.3389/fphar.2022.844567

9,462 views
14 citations

Mini Review

Published on 05 Apr 2022

Gut Microbiota Metabolism of Azathioprine: A New Hallmark for Personalized Drug-Targeted Therapy of Chronic Inflammatory Bowel Disease

in Drug Metabolism and Transport

Slavica Lazarević
Maja Đanic
Hani Al-Salami
Armin Mooranian
Momir Mikov

Frontiers in Pharmacology

doi 10.3389/fphar.2022.879170

6,201 views
10 citations

Original Research

Published on 05 Apr 2022

Single Dose Comparative Bioavailability Study of Lisdexamfetamine Dimesylate as Oral Solution Versus Reference Hard Capsules in Healthy Volunteers

in Drug Metabolism and Transport

Simona Rizea-Savu
Simona Nicoleta Duna
Dimitrios Panagiotopoulos
Roxana Colette Sandulovici

Frontiers in Pharmacology

doi 10.3389/fphar.2022.881198

6,483 views
1 citation

Original Research

Published on 01 Apr 2022

Identification of Natural Products as SENP2 Inhibitors for Targeted Therapy in Heart Failure

in Drug Metabolism and Transport

Somayye Taghvaei
Farzaneh Sabouni
Zarrin Minuchehr

Frontiers in Pharmacology

doi 10.3389/fphar.2022.817990

3,439 views
9 citations

Original Research

Published on 30 Mar 2022

Absorption, Metabolism, and Excretion of ACT-1004-1239, a First-In-Class CXCR7 Antagonist: In Vitro, Preclinical, and Clinical Data

in Drug Metabolism and Transport

Christine Huynh
Swen Seeland
Jerome Segrestaa
Carmela Gnerre
Jens Hogeback
Henriette E. Meyer zu Schwabedissen
Jasper Dingemanse
Patricia N. Sidharta

Frontiers in Pharmacology

doi 10.3389/fphar.2022.812065

3,213 views
2 citations

Original Research

Published on 25 Mar 2022

Changes in the Gut Microbiota May Affect the Clinical Efficacy of Oral Anticoagulants

in Drug Metabolism and Transport

Wenjun Chen
Jiafen Qian
Jinglan Fu
Tingting Wu
Meina Lv
Shaojun Jiang
Jinhua Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2022.860237

4,564 views
8 citations

Original Research

Published on 22 Mar 2022

Exploring the Potential Toxicological Mechanisms of Vine Tea on the Liver Based on Network Toxicology and Transcriptomics

in Drug Metabolism and Transport

Fangyu Xiao
Jihua Qiu
Ying Zhao

Frontiers in Pharmacology

doi 10.3389/fphar.2022.855926

3,105 views
7 citations

Original Research

Published on 18 Mar 2022

A Combined Pharmacometrics Analysis of Biomarker Distribution Under Treatment With Standard- or Low-Dose Rivaroxaban in Real-World Chinese Patients With Nonvalvular Atrial Fibrillation

in Drug Metabolism and Transport

Nan Zhao
Zhiyan Liu
Qiufen Xie
Zhe Wang
Zhongyi Sun
Qian Xiang
Yimin Cui

Frontiers in Pharmacology

doi 10.3389/fphar.2022.814724

2,873 views
5 citations

Review

Published on 18 Mar 2022

Genetic Polymorphisms and the Clinical Response to Systemic Lupus Erythematosus Treatment Towards Personalized Medicine

in Drug Metabolism and Transport

Melisa Intan Barliana
Nadiya Nurul Afifah
Riezki Amalia
Laniyati Hamijoyo
Rizky Abdulah

Frontiers in Pharmacology

doi 10.3389/fphar.2022.820927

5,949 views
6 citations

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Articles

Effect of Baicalein on the Pharmacokinetics of Cilostazol and Its Two Metabolites in Rat Plasma Using UPLC-MS/MS Method

Compatibility of Fuzi and Ginseng Significantly Increase the Exposure of Aconitines

Engineering of Stimulus-Responsive Pirfenidone Liposomes for Pulmonary Delivery During Treatment of Idiopathic Pulmonary Fibrosis

Single and Repeated Doses of EGb 761® do not Affect Pharmacokinetics or Pharmacodynamics of Rivaroxaban in Healthy Subjects

Dynamics of Erythroferrone Response to Erythropoietin in Rats

The Unusual Cosubstrate Specificity of NQO2: Conservation Throughout the Amniotes and Implications for Cellular Function

Urinary Profile of Endogenous Gamma-Hydroxybutyric Acid and its Biomarker Metabolites in Healthy Korean Females: Determination of Age-Dependent and Intra-Individual Variability and Identification of Metabolites Correlated With Gamma-Hydroxybutyric Acid

Dosage Strategy of Linezolid According to the Trough Concentration Target and Renal Function in Chinese Critically Ill Patients

Gut Microbiota Metabolism of Azathioprine: A New Hallmark for Personalized Drug-Targeted Therapy of Chronic Inflammatory Bowel Disease

Single Dose Comparative Bioavailability Study of Lisdexamfetamine Dimesylate as Oral Solution Versus Reference Hard Capsules in Healthy Volunteers

Identification of Natural Products as SENP2 Inhibitors for Targeted Therapy in Heart Failure

Absorption, Metabolism, and Excretion of ACT-1004-1239, a First-In-Class CXCR7 Antagonist: In Vitro, Preclinical, and Clinical Data

Changes in the Gut Microbiota May Affect the Clinical Efficacy of Oral Anticoagulants

Exploring the Potential Toxicological Mechanisms of Vine Tea on the Liver Based on Network Toxicology and Transcriptomics

A Combined Pharmacometrics Analysis of Biomarker Distribution Under Treatment With Standard- or Low-Dose Rivaroxaban in Real-World Chinese Patients With Nonvalvular Atrial Fibrillation

Genetic Polymorphisms and the Clinical Response to Systemic Lupus Erythematosus Treatment Towards Personalized Medicine