Frontiers in Pharmacology | Drug Metabolism and Transport

Methods

Published on 28 Aug 2023

Establishment of a sensitive UPLC-MS/MS method to quantify safinamide in rat plasma

in Drug Metabolism and Transport

Ying Wang
Guan-An Zhao
Xia Li
En Zhang
Wei Tan
Jia-qi Chen

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1211383

1,710 views
2 citations

Review

Published on 23 Aug 2023

Exosomes: potential diagnostic markers and drug carriers for adenomyosis

in Drug Metabolism and Transport

Wen-Xiu Cheng
Shao-Bin Wei
Yang Zhou
Yu Shao
Mao-Ya Li

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1216149

3,412 views
6 citations

Clinical Trial

Published on 23 Aug 2023

Safety, tolerability, pharmacokinetics, and pharmacodynamics of single and multiple doses of aficamten in healthy Chinese participants: a randomized, double-blind, placebo-controlled, phase 1 study

in Drug Metabolism and Transport

Xue Zhao
Hongzhong Liu
Wei Tian
Ligang Fang
Mengyang Yu
Xiaofei Wu
Aijing Liu
Ruijie Wan
Li Li
Jinghui Luo

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1227470

4,898 views
6 citations

Correction

Published on 22 Aug 2023

Corrigendum: Different pharmacokinetics of tramadol, O-demethyltramadol and N-demethyltramadol in postoperative surgical patients from those observed in medical patients

in Drug Metabolism and Transport

Nenad Neskovic
Dario Mandic
Saska Marczi
Sonja Skiljic
Gordana Kristek
Hrvoje Vinkovic
Boris Mraovic
Zeljko Debeljak
Slavica Kvolik

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1250698

1,002 views

Original Research

Published on 09 Aug 2023

Development of a robust UPLC-MS/MS method for the quantification of riluzole in human plasma and its application in pharmacokinetics

in Drug Metabolism and Transport

Zhuo Sun
Xin Liu
Wei Zuo
Qiang Fu
Tingting Xu
Liying Cui
Bo Zhang
Ying Peng

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1227354

2,052 views
2 citations

Original Research

Published on 28 Jul 2023

Differences in the pharmacokinetics and steady-state blood concentrations of orally administered lenvatinib in adult and juvenile rats

in Drug Metabolism and Transport

Xiaoyue Du
Hongxin Cai
Nan Jin
Zhiguo Wu
Lele Wang
Zeyu Wang
Baogang Xie

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1140849

1,811 views
1 citation

Original Research

Published on 20 Jul 2023

Physiologically-based pharmacokinetic modeling for single and multiple dosing regimens of ceftriaxone in healthy and chronic kidney disease populations: a tool for model-informed precision dosing

in Drug Metabolism and Transport

Fawaz Alasmari
Mohammed S. Alasmari
Hussa Mubarak Muwainea
Hatun A. Alomar
Abdullah F. Alasmari
Sary Alsanea
Aws Alshamsan
Muhammad F. Rasool
Faleh Alqahtani

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1200828

7,694 views
6 citations

Original Research

Published on 18 Jul 2023

CETP inhibitor evacetrapib enters mouse brain tissue

in Drug Metabolism and Transport

Jasmine Phénix
Jonathan Côté
Denis Dieme
Sherilyn J. Recinto
Felix Oestereich
Sasen Efrem
Sami Haddad
Michèle Bouchard
Lisa Marie Munter

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1171937

2,876 views
4 citations

Original Research

Published on 10 Jul 2023

Effects of bergapten on the pharmacokinetics of macitentan in rats both in vitro and in vivo

in Drug Metabolism and Transport

Jia Xu
Quan Zhou
Pengjiao Hou
Yu Wang
Peiwu Geng
Zebei Lu
Yunfang Zhou
Dapeng Dai
Shuanghu Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1204649

2,646 views
1 citation

Editorial

Published on 10 Jul 2023

Editorial: Drug metabolism and transport: the Frontier of personalized medicine

in Drug Metabolism and Transport

Junmin Zhang
Rong Wang
Sofia Azeredo Pereira

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1246827

2,090 views
2 citations

Original Research

Published on 07 Jul 2023

Absorption, tissue distribution, and excretion of glycycoumarin, a major bioactive coumarin from Chinese licorice (Glycyrrhiza uralensis Fisch)

in Drug Metabolism and Transport

Linhu Ye
Lei Cheng
Yan Deng
Sen Wang
Xinyu Wu
Shuiping Ou
Qi Chang
Xinqian Zhao
Wen Zhou
Jinghua Yu

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1216985

2,966 views
3 citations

Clinical Trial

Published on 07 Jul 2023

Safety and efficacy of oil palm phenolic supplementation in improving lipid profile among hyperlipidemic adults: a phase 2, randomized, double-blind, placebo-controlled clinical trial

in Drug Metabolism and Transport

Nur Balqis Muhammad Ismail Tadj
Nurul `Izzah Ibrahim
Tg Mohd Ikhwan Tg Abu Bakar Sidik
Mohamed S. Zulfarina
Qodriyah Haji Mohd Saad
Soon-Sen Leow
Syed Fairus
Isa Naina Mohamed

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1190663

2,983 views
1 citation

Original Research

Published on 05 Jul 2023

Pregnancy related hormones increase CYP3A mediated buprenorphine metabolism in human hepatocytes: a comparison to CYP3A substrates nifedipine and midazolam

in Drug Metabolism and Transport

Muluneh M. Fashe
Taryn A. Miner
John K. Fallon
Amanda P. Schauer
Craig Sykes
Philip C. Smith
Craig R. Lee

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1218703

2,827 views
6 citations

Mini Review

Published on 28 Jun 2023

Human induced pluripotent stem cell–derived liver-on-a-chip for studying drug metabolism: the challenge of the cytochrome P450 family

in Drug Metabolism and Transport

Isabel Tamargo-Rubio
Anna Bella Simpson
Joanne A. Hoogerland
Jingyuan Fu

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1223108

4,757 views
4 citations

Original Research

Published on 26 Jun 2023

Population pharmacokinetic analysis of transdermal granisetron in healthy Chinese and Caucasian volunteers

in Drug Metabolism and Transport

Jiayu Li
Pei Hu
Li Zhou
Fumiko Nagahama
Rui Chen

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1154026

2,350 views

Original Research

Published on 20 Jun 2023

Rhubarb polysaccharide and berberine co-assembled nanoparticles ameliorate ulcerative colitis by regulating the intestinal flora

in Drug Metabolism and Transport

Yifan Feng
Chenyang Wu
Huan Chen
Tingting Zheng
Hanyi Ye
Jinrui Wang
Yinghua Zhang
Jia Gao
Ying Li
Zhengqi Dong

Frontiers in Pharmacology

doi 10.3389/fphar.2023.1184183

5,063 views
10 citations