Original Research

Published on 21 Nov 2019

Choline Attenuates Cardiac Fibrosis by Inhibiting p38MAPK Signaling Possibly by Acting on M3 Muscarinic Acetylcholine Receptor

in Cardiovascular and Smooth Muscle Pharmacology

Lihui Zhao
Tingting Chen
Pengzhou Hang
Wen Li
Jing Guo
Yang Pan
Jingjing Du
Yuyang Zheng
Zhimin Du

Frontiers in Pharmacology

doi 10.3389/fphar.2019.01386

4,078 views
17 citations

Original Research

Published on 13 Nov 2019

Over-Expression of Inhibitor of Differentiation 2 Attenuates Post-Infarct Cardiac Fibrosis Through Inhibition of TGF-β1/Smad3/HIF-1α/IL-11 Signaling Pathway

in Cardiovascular and Smooth Muscle Pharmacology

Lin Yin
Ming-xin Liu
Wei Li
Feng-yuan Wang
Yan-hong Tang
Cong-xin Huang

Frontiers in Pharmacology

doi 10.3389/fphar.2019.01349

4,354 views
22 citations

Original Research

Published on 31 Oct 2019

Sophocarpine Suppresses NF-κB-Mediated Inflammation Both In Vitro and In Vivo and Inhibits Diabetic Cardiomyopathy

in Cardiovascular and Smooth Muscle Pharmacology

Fang Zou
Ling Wang
Han Liu
Wei Wang
Longlong Hu
Xiaoying Xiong
Lijuan Wu
Yunfeng Shen
Renqiang Yang

Frontiers in Pharmacology

doi 10.3389/fphar.2019.01219

3,824 views
24 citations

Original Research

Published on 29 Oct 2019

Sacubitril/Valsartan Improves Left Atrial and Left Atrial Appendage Function in Patients With Atrial Fibrillation and in Pressure Overload-Induced Mice

in Cardiovascular and Smooth Muscle Pharmacology

Ya Suo
Meng Yuan
Hongmin Li
Yue Zhang
Ying Li
Huaying Fu
Fei Han
Changhui Ma
Yuanyuan Wang
Qiankun Bao

Frontiers in Pharmacology

doi 10.3389/fphar.2019.01285

8,065 views
36 citations

Original Research

Published on 24 Oct 2019

Deletion of Neuropeptide Y Attenuates Cardiac Dysfunction and Apoptosis During Acute Myocardial Infarction

in Cardiovascular and Smooth Muscle Pharmacology

Wei Huang
Qianhui Zhang
Hanping Qi
Pilong Shi
Chao Song
Yongsheng Liu
Hongli Sun

Frontiers in Pharmacology

doi 10.3389/fphar.2019.01268

3,593 views
18 citations

Review

Published on 18 Oct 2019

The TRPA1 Channel in the Cardiovascular System: Promising Features and Challenges

in Cardiovascular and Smooth Muscle Pharmacology

Zhen Wang
Di Ye
Jing Ye
Menglong Wang
Jianfang Liu
Huimin Jiang
Yao Xu
Jishou Zhang
Jiangbin Chen
Jun Wan

Frontiers in Pharmacology

doi 10.3389/fphar.2019.01253

8,636 views
45 citations

Original Research

Published on 15 Oct 2019

AFC1 Compound Attenuated MI/R-Induced Ventricular Remodeling via Inhibiting PDGFR and STAT Pathway

in Cardiovascular and Smooth Muscle Pharmacology

Jie Liu
Xiaohui Zhou
Qingshu Meng
Kevin W. Huang
Jing Liu
Jinjun Tie
Rulin Zhuang
Guohan Chen
Yuhui Zhang
Lu Wei

Frontiers in Pharmacology

doi 10.3389/fphar.2019.01142

3,621 views
4 citations

Original Research

Published on 10 Oct 2019

Metabolomic Analysis of Platelets of Patients With Aspirin Non-Response

in Cardiovascular and Smooth Muscle Pharmacology

Jiun-Yang Chiang
Sheng-Han Lee
Yen-Ching Chen
Cho-Kai Wu
Jing-Yuan Chuang
Shyh-Chyi Lo
Huei-Ming Yeh
Shih-Fan Sherri Yeh
Cheng-An Hsu
Bin-Bin Lin

Frontiers in Pharmacology

doi 10.3389/fphar.2019.01107

5,231 views
11 citations

Original Research

Published on 08 Oct 2019

International Normalized Ratio as a Screening Test for Assessment of Anticoagulant Activity for Patients Treated With Rivaroxaban or Apixaban: A Pilot Study

in Cardiovascular and Smooth Muscle Pharmacology

Fanny Ofek
Dana Barchel
Nofar Perets
Tomer Ziv-Baran
Ahmad Mahajna
Talia Filipovich-Rimon
Osnat Garach-Jehoshua
Maya Berlin
Matitiahu Berkovitch

Frontiers in Pharmacology

doi 10.3389/fphar.2019.01177

6,274 views
4 citations

Original Research

Published on 04 Oct 2019

Propofol Induces Cardioprotection Against Ischemia-Reperfusion Injury via Suppression of Transient Receptor Potential Vanilloid 4 Channel

in Cardiovascular and Smooth Muscle Pharmacology

Binbin Wang
Qiongfeng Wu
Jie Liao
Shaoshao Zhang
Huixia Liu
Cui Yang
Qian Dong
Ning Zhao
Zhengrong Huang
Kefang Guo

Frontiers in Pharmacology

doi 10.3389/fphar.2019.01150

4,383 views
25 citations

Original Research

Published on 02 Oct 2019

Detection of Vasodilators From Herbal Components by a Transcriptome-Based Functional Gene Module Reference Approach

in Cardiovascular and Smooth Muscle Pharmacology

Peng Li
Chang Chen
Wuxia Zhang
Dingrong Yu
Shaoyan Liu
Jinzhong Zhao
An Liu

Frontiers in Pharmacology

doi 10.3389/fphar.2019.01144

6,040 views
4 citations

Original Research

Published on 27 Sep 2019

DiOHF Protects Against Doxorubicin-Induced Cardiotoxicity Through ERK1 Signaling Pathway

in Cardiovascular and Smooth Muscle Pharmacology

Danqi Chang
Hang Li
Cheng Qian
Yanggan Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2019.01081

4,620 views
21 citations

Correction

Published on 27 Sep 2019

Corrigendum: Ivabradine Treatment Reduces Cardiomyocyte Apoptosis in a Murine Model of Chronic Viral Myocarditis

in Cardiovascular and Smooth Muscle Pharmacology

Ge Li-Sha
Liu Li
Zhou De-Pu
Shi Zhe-Wei
Gu Xiaohong
Chen Guang-Yi
Li Jia
Lin Jia-Feng
Chu Maoping
Li Yue-Chun

Frontiers in Pharmacology

doi 10.3389/fphar.2019.01126

1,649 views
1 citation

Original Research

Published on 12 Sep 2019

Carvacrol Attenuates Diabetic Cardiomyopathy by Modulating the PI3K/AKT/GLUT4 Pathway in Diabetic Mice

in Cardiovascular and Smooth Muscle Pharmacology

Ning Hou
Yunpei Mai
Xiaoxia Qiu
Wenchang Yuan
Yilang Li
Chengfeng Luo
Yun Liu
Guiping Zhang
Ganjiang Zhao
Jian-dong Luo

Frontiers in Pharmacology

doi 10.3389/fphar.2019.00998

14,188 views
75 citations

Review

Published on 10 Sep 2019

Endoplasmic Reticulum Stress Activates Unfolded Protein Response Signaling and Mediates Inflammation, Obesity, and Cardiac Dysfunction: Therapeutic and Molecular Approach

in Cardiovascular and Smooth Muscle Pharmacology

Omar Mohammed Amen
Satyajit D. Sarker
Reena Ghildyal
Aditya Arya

Frontiers in Pharmacology

doi 10.3389/fphar.2019.00977

17,565 views
143 citations

Review

Published on 29 Aug 2019

Considerations for an In Vitro, Cell-Based Testing Platform for Detection of Drug-Induced Inotropic Effects in Early Drug Development. Part 2: Designing and Fabricating Microsystems for Assaying Cardiac Contractility With Physiological Relevance Using Human iPSC-Cardiomyocytes

in Cardiovascular and Smooth Muscle Pharmacology

Alexandre J. S. Ribeiro
Brian D. Guth
Michael Engwall
Sandy Eldridge
C. Michael Foley
Liang Guo
Gary Gintant
John Koerner
Stanley T. Parish
Jennifer B. Pierson

Frontiers in Pharmacology

doi 10.3389/fphar.2019.00934

11,060 views
37 citations

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Articles

Choline Attenuates Cardiac Fibrosis by Inhibiting p38MAPK Signaling Possibly by Acting on M3 Muscarinic Acetylcholine Receptor

Over-Expression of Inhibitor of Differentiation 2 Attenuates Post-Infarct Cardiac Fibrosis Through Inhibition of TGF-β1/Smad3/HIF-1α/IL-11 Signaling Pathway

Sophocarpine Suppresses NF-κB-Mediated Inflammation Both In Vitro and In Vivo and Inhibits Diabetic Cardiomyopathy

Sacubitril/Valsartan Improves Left Atrial and Left Atrial Appendage Function in Patients With Atrial Fibrillation and in Pressure Overload-Induced Mice

Deletion of Neuropeptide Y Attenuates Cardiac Dysfunction and Apoptosis During Acute Myocardial Infarction

The TRPA1 Channel in the Cardiovascular System: Promising Features and Challenges

AFC1 Compound Attenuated MI/R-Induced Ventricular Remodeling via Inhibiting PDGFR and STAT Pathway

Metabolomic Analysis of Platelets of Patients With Aspirin Non-Response

International Normalized Ratio as a Screening Test for Assessment of Anticoagulant Activity for Patients Treated With Rivaroxaban or Apixaban: A Pilot Study

Propofol Induces Cardioprotection Against Ischemia-Reperfusion Injury via Suppression of Transient Receptor Potential Vanilloid 4 Channel

Detection of Vasodilators From Herbal Components by a Transcriptome-Based Functional Gene Module Reference Approach

DiOHF Protects Against Doxorubicin-Induced Cardiotoxicity Through ERK1 Signaling Pathway

Corrigendum: Ivabradine Treatment Reduces Cardiomyocyte Apoptosis in a Murine Model of Chronic Viral Myocarditis

Carvacrol Attenuates Diabetic Cardiomyopathy by Modulating the PI3K/AKT/GLUT4 Pathway in Diabetic Mice

Endoplasmic Reticulum Stress Activates Unfolded Protein Response Signaling and Mediates Inflammation, Obesity, and Cardiac Dysfunction: Therapeutic and Molecular Approach

Considerations for an In Vitro, Cell-Based Testing Platform for Detection of Drug-Induced Inotropic Effects in Early Drug Development. Part 2: Designing and Fabricating Microsystems for Assaying Cardiac Contractility With Physiological Relevance Using Human iPSC-Cardiomyocytes