Review

Published on 03 Jun 2021

Analysis of Models of Doxorubicin-Induced Cardiomyopathy in Rats and Mice. A Modern View From the Perspective of the Pathophysiologist and the Clinician

in Cardiovascular and Smooth Muscle Pharmacology

Ekaterina Yu Podyacheva
Ekaterina A. Kushnareva
Andrei A. Karpov
Yana G. Toropova

Frontiers in Pharmacology

doi 10.3389/fphar.2021.670479

28,017 views
87 citations

Original Research

Published on 03 Jun 2021

miR-199a Overexpression Enhances the Potency of Human Induced-Pluripotent Stem-Cell–Derived Cardiomyocytes for Myocardial Repair

in Cardiovascular and Smooth Muscle Pharmacology

Weihua Bian
Wangping Chen
Thanh Nguyen
Yang Zhou
Jianyi Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2021.673621

3,668 views
15 citations

Methods

Published on 03 Jun 2021

Design and Methodology of a Multicenter Randomized Clinical Trial to Evaluate the Efficacy of Tongmai Jiangtang Capsules in Type 2 Diabetic Coronary Heart Disease Patients

in Cardiovascular and Smooth Muscle Pharmacology

Yu Wang
Yilei Guo
Ye Lei
Shuwei Huang
Liping Dou
Chang Li
Buchang Zhao
Wei Fu
Peng Zhou
Haitong Wan

Frontiers in Pharmacology

doi 10.3389/fphar.2021.625785

2,722 views
2 citations

Original Research

Published on 31 May 2021

Spironolactone Improves the All-Cause Mortality and Re-Hospitalization Rates in Acute Myocardial Infarction with Chronic Kidney Disease Patients

in Cardiovascular and Smooth Muscle Pharmacology

Xiang Qu
Hui Yao
Changxi Chen
Shuting Kong
Lingyue Sun
Leilei Du
Siqi Liang
Zhan Gao
Gaoshu Zheng
Minghua Zheng

Frontiers in Pharmacology

doi 10.3389/fphar.2021.632978

4,577 views
8 citations

Original Research

Published on 31 May 2021

Protective Effects of Sacubitril/Valsartan on Cardiac Fibrosis and Function in Rats With Experimental Myocardial Infarction Involves Inhibition of Collagen Synthesis by Myocardial Fibroblasts Through Downregulating TGF-β1/Smads Pathway

in Cardiovascular and Smooth Muscle Pharmacology

Meifang Wu
Yanguang Guo
Ying Wu
Kaizu Xu
Liming Lin

Frontiers in Pharmacology

doi 10.3389/fphar.2021.696472

4,148 views
14 citations

Original Research

Published on 28 May 2021

Increased Endogenous Activity of the Renin-Angiotensin System Reduces Infarct Size in the Rats with Early Angiotensin II-dependent Hypertension which Survive the Acute Ischemia/Reperfusion Injury

in Cardiovascular and Smooth Muscle Pharmacology

Zuzana Husková
Soňa Kikerlová
Janusz Sadowski
Petra Alánová
Lenka Sedláková
František Papoušek
Jan Neckář

Frontiers in Pharmacology

doi 10.3389/fphar.2021.679060

2,436 views
5 citations

Review

Published on 28 May 2021

MicroRNAs Regulating Mitochondrial Function in Cardiac Diseases

in Cardiovascular and Smooth Muscle Pharmacology

Guang-Qiong Zhang
Sheng-Quan Wang
Yan Chen
Ling-Yun Fu
Yi-Ni Xu
Ling Li
Ling Tao
Xiang-Chun Shen

Frontiers in Pharmacology

doi 10.3389/fphar.2021.663322

6,099 views
28 citations

Brief Research Report

Published on 28 May 2021

Apelin Does Not Impair Coronary Artery Relaxation Mediated by Nitric Oxide-Induced Activation of BKCa Channels

in Cardiovascular and Smooth Muscle Pharmacology

Amreen Mughal
Chengwen Sun
Stephen T. O’Rourke

Frontiers in Pharmacology

doi 10.3389/fphar.2021.679005

1,995 views
4 citations

Original Research

Published on 26 May 2021

Solifenacin/Mirabegron Induces an Acute Compliance Increase in the Filling Phase of the Capacity-Reduced Urinary Bladder: A Pressure-Volume Analysis in Rats

in Cardiovascular and Smooth Muscle Pharmacology

Hsien-Yu Peng
Cheng-Yuan Lai
Ming-Chun Hsieh
Tzer-Bin Lin

Frontiers in Pharmacology

doi 10.3389/fphar.2021.657959

3,090 views
5 citations

Review

Published on 26 May 2021

Direct Oral Anticoagulants: From Randomized Clinical Trials to Real-World Clinical Practice

in Cardiovascular and Smooth Muscle Pharmacology

Roberta Roberti
Luigi Francesco Iannone
Caterina Palleria
Antonio Curcio
Marco Rossi
Angela Sciacqua
Giuseppe Armentaro
Ada Vero
Antonia Manti
Velia Cassano

Frontiers in Pharmacology

doi 10.3389/fphar.2021.684638

20,701 views
52 citations

Original Research

Published on 25 May 2021

ANG II and Aldosterone Acting Centrally Participate in the Enhanced Sodium Intake in Water-Deprived Renovascular Hypertensive Rats

in Cardiovascular and Smooth Muscle Pharmacology

Gabriela Maria Lucera
José Vanderlei Menani
Eduardo Colombari
Débora Simões Almeida Colombari

Frontiers in Pharmacology

doi 10.3389/fphar.2021.679985

2,730 views
5 citations

Original Research

Published on 24 May 2021

Astragaloside IV Attenuates the Myocardial Injury Caused by Adriamycin by Inhibiting Autophagy

in Cardiovascular and Smooth Muscle Pharmacology

Li-Fei Luo
Lu-Yun Qin
Jian-Xin Wang
Peng Guan
Na Wang
En-Sheng Ji

Frontiers in Pharmacology

doi 10.3389/fphar.2021.669782

3,796 views
19 citations

Original Research

Published on 21 May 2021

Dexmedetomidine Protects Human Cardiomyocytes Against Ischemia-Reperfusion Injury Through α2-Adrenergic Receptor/AMPK-Dependent Autophagy

in Cardiovascular and Smooth Muscle Pharmacology

Yingying Xiao
Junpeng Li
Lisheng Qiu
Chuan Jiang
Yanhui Huang
Jinfen Liu
Qi Sun
Haifa Hong
Lincai Ye

Frontiers in Pharmacology

doi 10.3389/fphar.2021.615424

4,019 views
13 citations

Original Research

Published on 21 May 2021

Identification of Docetaxel as a Potential Drug to Promote HDL Biogenesis

in Cardiovascular and Smooth Muscle Pharmacology

Hong Y. Choi
Isabelle Ruel
Jacques Genest

Frontiers in Pharmacology

doi 10.3389/fphar.2021.679456

2,505 views
6 citations

Original Research

Published on 19 May 2021

Dapsone Ameliorates Isoproterenol-Induced Myocardial Infarction via Nrf2/ HO-1; TLR4/ TNF-α Signaling Pathways and the Suppression of Oxidative Stress, Inflammation, and Apoptosis in Rats

in Cardiovascular and Smooth Muscle Pharmacology

Walaa Yehia Abdelzaher
Sabreen Mahmoud Ahmed
Nermeen N. Welson
Khalaf F. Alsharif
Gaber El-Saber Batiha
Dina A. Aly Labib

Frontiers in Pharmacology

doi 10.3389/fphar.2021.669679

7,373 views
37 citations

Original Research

Published on 18 May 2021

Tanshinone I Inhibits Oxidative Stress–Induced Cardiomyocyte Injury by Modulating Nrf2 Signaling

in Cardiovascular and Smooth Muscle Pharmacology

Yu-Ting Wu
Ling-Peng Xie
Yue Hua
Hong-Lin Xu
Guang-Hong Chen
Xin Han
Zhang-Bin Tan
Hui-Jie Fan
Hong-Mei Chen
Jun Li

Frontiers in Pharmacology

doi 10.3389/fphar.2021.644116

4,304 views
23 citations

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Articles

Analysis of Models of Doxorubicin-Induced Cardiomyopathy in Rats and Mice. A Modern View From the Perspective of the Pathophysiologist and the Clinician

miR-199a Overexpression Enhances the Potency of Human Induced-Pluripotent Stem-Cell–Derived Cardiomyocytes for Myocardial Repair

Design and Methodology of a Multicenter Randomized Clinical Trial to Evaluate the Efficacy of Tongmai Jiangtang Capsules in Type 2 Diabetic Coronary Heart Disease Patients

Spironolactone Improves the All-Cause Mortality and Re-Hospitalization Rates in Acute Myocardial Infarction with Chronic Kidney Disease Patients

Protective Effects of Sacubitril/Valsartan on Cardiac Fibrosis and Function in Rats With Experimental Myocardial Infarction Involves Inhibition of Collagen Synthesis by Myocardial Fibroblasts Through Downregulating TGF-β1/Smads Pathway

Increased Endogenous Activity of the Renin-Angiotensin System Reduces Infarct Size in the Rats with Early Angiotensin II-dependent Hypertension which Survive the Acute Ischemia/Reperfusion Injury

MicroRNAs Regulating Mitochondrial Function in Cardiac Diseases

Apelin Does Not Impair Coronary Artery Relaxation Mediated by Nitric Oxide-Induced Activation of BKCa Channels

Solifenacin/Mirabegron Induces an Acute Compliance Increase in the Filling Phase of the Capacity-Reduced Urinary Bladder: A Pressure-Volume Analysis in Rats

Direct Oral Anticoagulants: From Randomized Clinical Trials to Real-World Clinical Practice

ANG II and Aldosterone Acting Centrally Participate in the Enhanced Sodium Intake in Water-Deprived Renovascular Hypertensive Rats

Astragaloside IV Attenuates the Myocardial Injury Caused by Adriamycin by Inhibiting Autophagy

Dexmedetomidine Protects Human Cardiomyocytes Against Ischemia-Reperfusion Injury Through α2-Adrenergic Receptor/AMPK-Dependent Autophagy

Identification of Docetaxel as a Potential Drug to Promote HDL Biogenesis

Dapsone Ameliorates Isoproterenol-Induced Myocardial Infarction via Nrf2/ HO-1; TLR4/ TNF-α Signaling Pathways and the Suppression of Oxidative Stress, Inflammation, and Apoptosis in Rats

Tanshinone I Inhibits Oxidative Stress–Induced Cardiomyocyte Injury by Modulating Nrf2 Signaling