Frontiers in Pharmacology

Original Research

Accepted on 14 Apr 2025

Elucidation of the Antipyretic and Anti-inflammatory Effect of 8-O-Acetyl Shanzhiside methyl ester Based on Intestinal Flora and Metabolomics Analysis

in Ethnopharmacology

Xiaolin Li
Tianlong Liu
Keke Liang
Renjie Wang
Jun Yang
Yidan Chen
Rong Wang
Maoxing Li

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1482323

Clinical Trial

Accepted on 14 Apr 2025

Efficacy and safety of Traditional Chinese Medicine Elian Granule for chronic atrophic gastritis: A multi-center, randomized, double-blind, placebo-controlled study

in Ethnopharmacology

Qingling Jia
Yuebo Jia
Yongqi Chen
Likun Guo
Chenheng Wu
Jun Cong
Zhijian Gu
Xuejun Li
Fang Shengquan
Zhuhua Liu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1545313

Original Research

Accepted on 14 Apr 2025

Regulation of autophagy by the PI3K-AKT pathway in Astragalus membranaceus -Cornus officinalis to ameliorate diabetic nephropathy

in Ethnopharmacology

Rui Zhang
Xushan Lan
Wenhui Zhu
Lifan Wang
Peng Liu
Ping Li

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1505637

Original Research

Accepted on 14 Apr 2025

Understanding the Ancient Classic and Famous Prescriptions via the Property of Chinese Materia Medica

in Ethnopharmacology

Dan Qin
He Zhang
Bin Du
HUI WANG
Ligang Liu
Yun Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1551531

Review

Accepted on 14 Apr 2025

Gastrointestinal Injury in Cardiopulmonary Bypass: Current Insights and Future Directions Author names and affiliations

in Gastrointestinal and Hepatic Pharmacology

Qi-long Mao
Zi-Hang Yu
Liang Nie
Feixiang Wang
Yu-Hui Dong
Xiaofei Qi

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1542995

Original Research

Accepted on 14 Apr 2025

Tamarix honey phenolics attenuate cisplatin-induced kidney toxicity by inhibition of inflammation mediated IL-6/STAT3/TNF-α and oxidative stress-dependent Nrf2/caspase-3 apoptotic signaling pathways

in Ethnopharmacology

Hanan Aati
Sultan Aati
Hebatallah Bahr
Asmaa Abdelsattar
Marwa Embaby
Ahmed Reda
Usama Ramadan Abdelmohsen
Gerhard Bringmann
Hossam M Hassan
Mostafa A. Darwish

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1584832

Review

Accepted on 14 Apr 2025

Paris spp. (Liliaceae): A review of Its Botany, Ethnopharmacology, Phytochemistry, Pharmacological Activities, and Practical Applications

in Ethnopharmacology

Zhou Ji
Liao Bin Bin
Miao Ju Lian
Chen Xu Bing

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1570818

Original Research

Accepted on 14 Apr 2025

Irisin restrains neuroinflammation in mouse experimental autoimmune encephalomyelitis via regulating microglia activation

in Inflammation Pharmacology

Qiuxia Zhang
Lin-Jie Zhang
Ning Zhang
Li Yang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1561939

Mini Review

Accepted on 14 Apr 2025

The role of glutamate dehydrogenase in the ageing brain

in Neuropharmacology

Tao Zhou
Haichuan Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1586655

Review

Accepted on 14 Apr 2025

Current insights and prospects for the pathogenesis and treatment of clinical manifestations associated with Down syndrome through neurotransmitter, inflammatory, and oxidative stress pathways

in Neuropharmacology

Fawaz Alasmari
Ashfaq Ahmad
Sary Alsanea
Alaa Hammad
Walid Al-Qerem

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1592277

Original Research

Accepted on 14 Apr 2025

SuoquanYishen Formula improves renal cellular senescence by inhibiting YTHDF1-Rubicon axis to promote autophagy in diabetic kidney disease

in Renal Pharmacology

Zijie Yan
Lin Zhang
Tianpeng Ma
Yong Yuan
Yu Kang
Shuman Liu
BoCen Chen
Kai Li
Man Xiao
Yiqiang Xie

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1543277

Original Research

Accepted on 14 Apr 2025

Signal mining and analysis of sepsis-related adverse events in patients using immunosuppressive drugs based on the FDA Adverse Event Reporting System(FAERS)database

in Inflammation Pharmacology

XueHui Zhou
Hao Chen
Qiao-Lian Xu
Jia-Kui Sun

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1598433

Systematic Review

Accepted on 14 Apr 2025

Effectiveness and Safety of Single Anti-Seizure Medication as Adjunctive Therapy for Drug-Resistant Focal Epilepsy based on Network Meta-Analysis

in Neuropharmacology

Nian-Jia Deng
Zhixin Zhang
Chen-Yang Xian-Yu
Yu-Ting Tao
Yu-Tong Ma
Hui-Jun Li
Teng-Yu Gao
Xin Liu
Jie Luo
Chao Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1500475

Original Research

Accepted on 14 Apr 2025

Hydroxychloroquine increases the exposure of methotrexate in plasma and red blood cells: A Pharmacokinetic Interaction Study in Rats In Vivo

in Drug Metabolism and Transport

Guijie Zhang
Rui Wang
Geping Chen
Simin Liu
Hongyu Jie
Wenying Chen
Qiang Li

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1561001

Clinical Trial

Accepted on 14 Apr 2025

Randomized, Double-blind, Placebo-Controlled Pilot Study of Metformin as an Adjunctive Therapy in Parkinson's disease

in Translational Pharmacology

Mostafa Bahaa
Hayam Ali Alrasheed
Thanaa A Elmasry
Eman I Elberri
Fedaa A Kotkata
Ramy M El Sabaa
Yasmine M Elmorsi
Mostafa M Kamel
Walaa A Negm
Amir O Hamouda

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1497261

Editorial

Accepted on 14 Apr 2025

Editorial: "The interplay between chronic pain and affective-cognitive alterations: shared neural mechanisms, circuits, and treatment"

in Neuropharmacology

Luca Posa
Danilo De Gregorio
Kelly Smart
Serena Boccella

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1605670