Case Report

Accepted on 18 Nov 2024

Case report: Effective Combination Therapy with Afatinib and Anlotinib in Lung Adenocarcinoma with Uncommon EGFR L858M/L861R Mutations

in Pharmacology of Anti-Cancer Drugs

Yueming He
Yitao Wu
Rongqi He
Meng Xu
Heshan Chen
Yiran Meng
Liuqing Zheng
Li Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1437086

Original Research

Published on 18 Nov 2024

Effect of Coptidis Rhizoma on gastrointestinal system before and after processing with wine based on gut microbiota and short chain fatty acids

in Ethnopharmacology

Rui Tian
Wen-Xiao Wang
Ya-Ya Bai
Yu-Ping Tang
Qiao Zhang
Shi-Jun Yue

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1492047

240 views

Original Research

Published on 18 Nov 2024

Comparative bactericidal activity of four macrolides alone and combined with rifampicin or doxycycline against Rhodococcus equi at concentrations achievable in foals

in Pharmacology of Infectious Diseases

Anne-Sophie Huguet
Ophélie Gourbeyre
Agathe Bernand
Charline Philibert
Alain Bousquet-Melou
Elodie A. Lallemand
Aude A. Ferran

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1458496

288 views

Original Research

Published on 18 Nov 2024

Qingre Huoxue decoction attenuates myocardial ischemia‒reperfusion injury by regulating the autophagy‒endoplasmic reticulum stress axis via FAM134B-mediated ER-phagy

in Ethnopharmacology

Rui Li
Jiechun Zhang
Shuliang Ji
Junfeng Fang
Xiaodong Ji
Yanping Zeng
Nan Liu
Wei Wu
Shiyi Liu

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1447610

298 views

Systematic Review

Published on 18 Nov 2024

Efficacy and safety of Epimedium total flavonoids for primary osteoporosis: a systematic review and meta-analysis

in Experimental Pharmacology and Drug Discovery

Jinkun Li
Xudong Huang
Yifeng Yuan
Haixin Zhang
Hang Zhou
Wei Xiong
Yuyi Li
Zechen Zhang
Fengqing Qie
Yingdelong Mao

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1505926

177 views

Methods

Published on 18 Nov 2024

Protocol of REACH-01: a single-arm, open label, prospective study of HAIC sequential TAE combined with tislelizumab and surufatinib in unresectable intrahepatic cholangiocarcinoma

in Pharmacology of Anti-Cancer Drugs

Kang-shuai Li
Yi Liu
Tie-zhong Zhang
Yun-fei Xu
Zong-li Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1435639

112 views

Original Research

Published on 18 Nov 2024

Investigation on regulation of N-acetyltransferase 2 expression by nuclear receptors in human hepatocytes

in Pharmacogenetics and Pharmacogenomics

Kyung U. Hong
Anthony P. Aureliano
Kennedy M. Walls
David W. Hein

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1488367

221 views

Correction

Published on 18 Nov 2024

Corrigendum: Sini san regulates intestinal flora and short-chain fatty acids to ameliorate hepatocyte apoptosis and relieve CCl4-induced liver fibrosis in mice

in Ethnopharmacology

Qiong Wu
Fangsi Zhu
Yu Yao
Luyun Chen
Yijie Ding
Yong Su
Chaoliang Ge

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1516840

Original Research

Published on 18 Nov 2024

Maslinic acid induces autophagy and ferroptosis via transcriptomic and metabolomic reprogramming in prostate cancer cells

in Pharmacology of Anti-Cancer Drugs

Fen Hu
Yuxi Sun
Yunfeng Zhang
Jiaxin Chen
Yingzi Deng
Yifei Li
Ruobing Li
Juan Zhang
Yongping Liang
Yan Liu

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1453447

202 views

Original Research

Published on 18 Nov 2024

Increase in body weight is lowered when mice received fecal microbiota transfer from donor mice treated with the AT1 receptor antagonist telmisartan

in Cardiovascular and Smooth Muscle Pharmacology

Marco L. Freschi
Axel Künstner
Gianna Huber
Ines Stölting
Hauke Busch
Misa Hirose
Walter Raasch

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1453989

132 views

Original Research

Published on 18 Nov 2024

Integrated chemical analysis, metabolic profiling, network pharmacology, molecular docking and toxicity prediction to reveal the active ingredients and their safety of raw and prepared rhubarbs in the treatment of gastric ulcers

in Experimental Pharmacology and Drug Discovery

Chenxi Wang
Xin Zhao
Jingjing Jiang
Mengqi Jia
Wenqing Shi
Zhenghua Wu
Shiyu Feng
Guorong Fan
Yuefen Lou

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1481091

274 views

Original Research

Published on 18 Nov 2024

Chrysanthemum indicum L. ameliorates muscle atrophy by improving glucose tolerance in CT26-induced cancer cachexia

in Ethnopharmacology

Gahee Song
Minji Choi
Woo Yong Park
Sang Hee Kim
Wenjun Jiao
Ja Yeon Park
Kwang Seok Ahn
Hyun Jeong Kwak
Jae-Young Um

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1455805

193 views

Original Research

Published on 18 Nov 2024

Efficient generation of HPLC and FTIR data for quality assessment using time series generation model: a case study on Tibetan medicine Shilajit

in Ethnopharmacology

Rong Ding
Shiqi He
Xuemei Wu
Liwen Zhong
Guopeng Chen
Rui Gu

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1503508

239 views

Original Research

Published on 18 Nov 2024

Pharmacological rescue of the G85E CFTR variant by preclinical and approved modulators

in Pharmacology of Ion Channels and Channelopathies

Valeria Tomati
Valeria Capurro
Emanuela Pesce
Cristina Pastorino
Elvira Sondo
Mariateresa Lena
Anna Borrelli
Federico Cresta
Stefano Pantano
Francesca Collini

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1494327

180 views

Review

Published on 18 Nov 2024

Amentoflavone for treating cardiocerebrovascular diseases and neurological disorders

in Cardiovascular and Smooth Muscle Pharmacology

Hang Zhang
Yin-mei Ban
De-mei Li
Gang Wang
Juan Gu
Lei Zhu

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1406510

Clinical Trial

Accepted on 15 Nov 2024

Pharmacokinetics, Pharmacodynamics and Bioavailability of Dexmedetomidine Nasal Spray in Healthy Chinese Adults: a Phase I Clinical Trial

in Translational Pharmacology

Yan Li
Lu Qi
Zhenyu Wang
Wan Wang
Langxi Zhang
Leting Yang
Chen Liu
Wenjing Zhong
Xinghe Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1488462

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Articles

Case report: Effective Combination Therapy with Afatinib and Anlotinib in Lung Adenocarcinoma with Uncommon EGFR L858M/L861R Mutations

Effect of Coptidis Rhizoma on gastrointestinal system before and after processing with wine based on gut microbiota and short chain fatty acids

Comparative bactericidal activity of four macrolides alone and combined with rifampicin or doxycycline against Rhodococcus equi at concentrations achievable in foals

Qingre Huoxue decoction attenuates myocardial ischemia‒reperfusion injury by regulating the autophagy‒endoplasmic reticulum stress axis via FAM134B-mediated ER-phagy

Efficacy and safety of Epimedium total flavonoids for primary osteoporosis: a systematic review and meta-analysis

Protocol of REACH-01: a single-arm, open label, prospective study of HAIC sequential TAE combined with tislelizumab and surufatinib in unresectable intrahepatic cholangiocarcinoma

Investigation on regulation of N-acetyltransferase 2 expression by nuclear receptors in human hepatocytes

Corrigendum: Sini san regulates intestinal flora and short-chain fatty acids to ameliorate hepatocyte apoptosis and relieve CCl4-induced liver fibrosis in mice

Maslinic acid induces autophagy and ferroptosis via transcriptomic and metabolomic reprogramming in prostate cancer cells

Increase in body weight is lowered when mice received fecal microbiota transfer from donor mice treated with the AT1 receptor antagonist telmisartan

Integrated chemical analysis, metabolic profiling, network pharmacology, molecular docking and toxicity prediction to reveal the active ingredients and their safety of raw and prepared rhubarbs in the treatment of gastric ulcers

Chrysanthemum indicum L. ameliorates muscle atrophy by improving glucose tolerance in CT26-induced cancer cachexia

Efficient generation of HPLC and FTIR data for quality assessment using time series generation model: a case study on Tibetan medicine Shilajit

Pharmacological rescue of the G85E CFTR variant by preclinical and approved modulators

Amentoflavone for treating cardiocerebrovascular diseases and neurological disorders

Pharmacokinetics, Pharmacodynamics and Bioavailability of Dexmedetomidine Nasal Spray in Healthy Chinese Adults: a Phase I Clinical Trial