Frontiers in Pharmacology

Original Research

Published on 01 Apr 2025

GraphTransNet: predicting epilepsy-related genes using a graph-augmented protein language model

in Experimental Pharmacology and Drug Discovery

Junfeng Xie
Wei Li
Hairu You
Dafang Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1584625

398 views

Original Research

Published on 01 Apr 2025

A novel antidepressant mechanism of baicalin: enhancing KIF5A-mediated axoplasmic transport and vesicular trafficking in glutamatergic neurons

in Neuropharmacology

Shuaifei Lu
Jiduo Shen
Xiaohui Jin
Changjing Zhang
Baoying Wang
Xianghua Liu
Ming Bai
Erping Xu
Xiangli Yan
Yucheng Li

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1577676

460 views

Original Research

Published on 01 Apr 2025

Increase of Brivaracetam serum concentration with introduction of Cenobamate

in Neuropharmacology

Lena Bender
Martin Hirsch
Andreas Schulze-Bonhage

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1571376

581 views

Review

Published on 01 Apr 2025

Natural compounds: new therapeutic approach for inhibition of Streptococcus mutans and dental caries

in Pharmacology of Infectious Diseases

Milad Kashi
Mahdieh Varseh
Yasaman Hariri
Zahra Chegini
Aref Shariati

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1548117

669 views

Original Research

Published on 01 Apr 2025

Gallic acid mitigates high-fat and high-carbohydrate diet-induced steatohepatitis by modulating the IRF6/PPARγ signaling pathway

in Ethnopharmacology

Jiahao Qiu
Lihong Fu
Yan Xue
Yilan Yang
Fengjie Qiao
Wanchun Zhu
Yating Gao
Miao Fang
Yufei Liu
Zhujun Gao

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1563561

586 views

Original Research

Published on 01 Apr 2025

Metal-phenolic nanozyme as a ferroptosis inhibitor for alleviating cisplatin-induced acute kidney injury

in Inflammation Pharmacology

Yunfeng Xiong
Huimin Kang
Yanping Rao
Xiayu Huang
Yang Zhu
Lixin Wei

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1535969

526 views

Original Research

Published on 01 Apr 2025

New prognostic features and personalized treatment strategies of mitochondrial related genes in colorectal cancer patients

in Pharmacology of Anti-Cancer Drugs

Qizheng Xu
Zhiwen Wang
Shan-Tao Huang
Jia-Yu Shi
Yan Zhu
Han-Qing Pang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1540767

299 views

Original Research

Published on 01 Apr 2025

Exploring the impact of cuproptosis on prostate cancer prognosis via RNA methylation regulation based on single cell and bulk RNA sequencing data

in Pharmacology of Anti-Cancer Drugs

Junchao Wu
Wentian Wu
Jiaxuan Qin
Ziqi Chen
Rongfang Zhong
Peng Guo
Song Fan

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1573611

482 views

Clinical Trial

Published on 01 Apr 2025

First-in-human study of CPL’116 – a dual JAK/ROCK inhibitor – in healthy subjects

in Inflammation Pharmacology

Piotr J. Rudzki
Katarzyna Jarus-Dziedzic
Dorota Włodarczyk
Michał Kaza
Piotr Pankiewicz
Agnieszka Gierczak-Pachulska
Martyna Banach
Beata Zygmunt
Cezary Piwowarczyk
Paweł Żero

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1583723

602 views

Original Research

Published on 01 Apr 2025

A real-world pharmacovigilance study of adverse drug reactions associated with lecanemab and aducanumab based on WHO-VigiAccess and FAERS databases

in Neuropharmacology

Haoxiang Hu
Yunhan Zhao
Jiesheng Mao
Jianghai He
Yihan Zhang
Hongyu Ye
Xiaokai Yang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1561020

524 views

Systematic Review

Published on 01 Apr 2025

Efficacy and safety of tirabrutinib monotherapy in relapsed or refractory B-cell lymphomas/leukemia: a meta-analysis

in Pharmacology of Anti-Cancer Drugs

Jingfei Wang
Hai-en Cheng
Yanhua Sun
Zhenfeng Li
Yunke Zang
Yuying Zhao
Guimao Yang
Zhijun Liu
Yaqi Sun
Yanli Sun

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1559056

788 views

Original Research

Published on 01 Apr 2025

A real-world pharmacovigilance analysis of omadacycline in FDA adverse event reporting system (FAERS) database

in Inflammation Pharmacology

Xueping Shi
Chen Wang
Xiang Liu
Li Zou
Pei Guo

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1558868

561 views

Original Research

Published on 01 Apr 2025

Berberis vulgaris fruit extract mitigated apoptosis in experimentally induced testicular ischemia and reperfusion injury in rats

in Ethnopharmacology

Serdar Yigit
Sakir Akgun
Isa Yesilyurt
Soner Bitiktas
Ergin Taskin
Ali Alper Kahraman
Muhammed Yayla
Pınar Aksu Kilicle
Seyit Ali Bingol
Bengul Ozdemir

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1514676

335 views

Brief Research Report

Published on 01 Apr 2025

Clopidogrel transfer into human milk: case series – a contribution from the ConcePTION project

in Obstetric and Pediatric Pharmacology

Martje Van Neste
Nina Nauwelaerts
Raf Mols
Kaytlin Krutsch
Michael Ceulemans
Anneke Passier
Anne Smits
Pieter Annaert
Karel Allegaert

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1499243

550 views

Review

Published on 01 Apr 2025

Traditional uses and emerging therapeutic potential of Typha angustifolia L.: insights into its phytochemistry, pharmacological activities and quality control

in Ethnopharmacology

Junyu Liu
Ziyi Chen
Sian Tao
Xinyao Shu
Bingjie Shao
Xiaobo Zhang
Yang Yang
Xiaoli Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1557136

328 views

Systematic Review

Published on 01 Apr 2025

Inflammatory bowel disease therapeutics: a bibliometric analysis of tofacitinib research in ulcerative colitis

in Gastrointestinal and Hepatic Pharmacology

Jianping Zhou
Yuting Xi
Yaping Zhang
Rui Zhang
Hao Fu
Ce Zhou

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1570238

588 views