Frontiers in Pharmacology

Original Research

Published on 04 Apr 2025

Evaluating the anti-neuropathic effects of the thymol-loaded nanofibrous scaffold in a rat model of spinal cord injury

in Ethnopharmacology

Roshanak Amirian
Pardis Mohammadi Pour
Hassan Maleki
Sajad Fakhri
Sedigheh Asgary
Mohammad Hossein Farzaei
Javier Echeverría

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1507397

392 views

Original Research

Published on 04 Apr 2025

Incidence and determinants of excessive weight gain in people living with HIV initiating tenofovir, lamivudine, and dolutegravir-based therapy: a multicenter retrospective study in northwest Ethiopia

in Pharmacoepidemiology

Gashaw Sisay Chanie
Wagaye Atalay
Tirsit Ketsela Zeleke
Zemenu Wube Bayleyegn
Yonas Sisay Aragie
Gizachew Kassahun Bizuneh
Mihret Melese
Rahel Belete Abebe

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1394458

437 views

Original Research

Published on 04 Apr 2025

Suppressed intestinal secondary bile acids in moxifloxacin-induced hyperglycemia: studies in normal and diabetic GK rats

in Gastrointestinal and Hepatic Pharmacology

Yewen Sun
Yuchen Qu
Zhuan Yang
Bo Lv
Guanjun Wang
Kai Fan
Yuyuan Wang
Jie Pan
Ziyan Du
Yunli Yu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1569856

326 views

Original Research

Published on 04 Apr 2025

Eculizumab is efficacious and safe in pediatric patients with various forms of hemolytic uremic syndrome: a retrospective clinical experience of a tertiary center

in Renal Pharmacology

Naama Lax
Miriam Davidovits
Gabriel Chodick
Yael Bernfeld
Orit Peled

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1535407

375 views

Original Research

Published on 04 Apr 2025

MiR-3613-5p targets AQP4 to promote the progression of chronic atrophic gastritis to gastric cancer

in Gastrointestinal and Hepatic Pharmacology

Jian Bi
Yufen Wang
Yingde Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1523689

304 views

Original Research

Published on 04 Apr 2025

Bone loss in young adults with HIV following antiretroviral therapy containing tenofovir disoproxil fumarate regimen using machine learning

in Pharmacology of Infectious Diseases

Ling Chen
Jia Tang
Leidan Zhang
Liyuan Zheng
Fada Wang
Fuping Guo
Yang Han
Xiaojing Song
Wei Lv
Wei Cao

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1516013

338 views

Original Research

Published on 04 Apr 2025

Landscape analysis of m6A modification regulators reveals LRPPRC as a key modulator in tubule cells for DKD: a multi-omics study

in Renal Pharmacology

Li Jiang
Hongda Yu
Jie Jian
Xulin Sai
Yudian Wang
Yufei Zhang
Xiai Wu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1506896

224 views

Original Research

Published on 04 Apr 2025

Composite outcome of oral azvudine vs. nirmatrelvir-ritonavir in COVID-19 patients: a retrospective cohort study

in Pharmacology of Infectious Diseases

Jingxia Chen
Zhengyue Liu
Ruolin Liu
Chengxin Su
Yunyun Yang
Zhuo Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1546787

241 views

Review

Published on 04 Apr 2025

The emerging role of vascular endothelial cell-mediated angiogenesis in the imbalance of RA synovial microenvironment and its clinical relevance

in Inflammation Pharmacology

Xingxing Huo
Yanhui Peng
Hui Li
Chen Li
Faxue Liao
Chenggui Miao
Yurong Huang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1481089

267 views

Original Research

Published on 04 Apr 2025

Multi-tissue metabolomics analysis reveals susceptible factors for chemotherapy-induced hepatotoxicity in colorectal cancer patients

in Drug Metabolism and Transport

Huilin Xu
Mingming Li
Houshan Yao
Guoliang Chen
Jiani Chen
Xinyun Hou
Hong Yang
Chenghang Yu
Zeshuai Lin
Jiawei Zhu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1517446

314 views

Original Research

Published on 04 Apr 2025

Endoplasmic reticulum stress aggravates ferroptosis via PERK/ATF4/HSPA5 pathway in UUO-induced renal fibrosis

in Renal Pharmacology

Zhigang Huang
Lihua Zhou
Bin Liu
Xiaoju Li
Yu Sang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1545972

249 views

Review

Published on 04 Apr 2025

Acacetin as a natural cardiovascular therapeutic: mechanisms and preclinical evidence

in Cardiovascular and Smooth Muscle Pharmacology

Zihe Zhou
Tao Li
Helin Qin
Xinyu Wang
Shanshan He
Zhongcai Fan
Qiang Ye
Yanfei Du

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1493981

434 views

Original Research

Published on 04 Apr 2025

Alpha-estradiol and (R)-(−)-ibuprofen inhibit gastric cancer progression via GLI1 G-quadruplex

in Gastrointestinal and Hepatic Pharmacology

Qiang Li
Pan Pan
Qingqing Xian
Jingtan Li
Jingting Wang
Jiaying Cai
Jing Wang
Yanfei Jia
Haiji Sun
Lulu Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1492694

277 views

Original Research

Accepted on 03 Apr 2025

Hochuekkito accelerates recovery from cisplatin induced-muscle atrophy accompanied by slow-twitch fiber-specific microRNA upregulation in mice

in Ethnopharmacology

Hitomi Sekine
Chinami Matsumoto
Naoki Fujitsuka
Sachiko Mogami
Shunsuke Ohnishi
Hiroshi Takeda

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1502563

Systematic Review

Accepted on 03 Apr 2025

Tailoring Dual Antiplatelet Therapy for Stroke Prevention: A Meta-Analysis of Timing, Duration, and Stroke Subtypes

in Neuropharmacology

NAIF M. ALHAWITI
Sherouk Fouda
Naser D. Alotaibi
Hassan A. Madkhali
Fahad K. Alsharef
Ashraf El-Metwally
Jamal M Alhawiti

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1516402

Original Research

Accepted on 03 Apr 2025

Pulmonary Artery-Targeted Low-Dose Metformin-Loaded Nanocapsules Safely Improve Pulmonary Arterial Hypertension in Rats

in Cardiovascular and Smooth Muscle Pharmacology

Ayako Chida-Nagai
Naoki Masaki
Hiroki Sato
Tatsuya Kato
Emi Takakuwa
Yoshihiro Matsuno
Atsushi Manabe
Atsuhito Takeda

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1577570

119 views