Frontiers in Pharmacology

Original Research

Published on 08 Apr 2025

Molecular mechanisms of the anchang group prescription in treating radiation enteritis: network pharmacology analysis and experimental evidence

in Experimental Pharmacology and Drug Discovery

Wei Liang
Bo Li
Yuehong Sun
Dapeng Jia
Tingting Hu
Rujing Huang
Zhilong Liu
Huan Yang
Baocai Chen
Xiaoming Yin

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1524925

249 views

Original Research

Published on 08 Apr 2025

Risk of medication-induced lactic acidosis and hyperlactatemia: a pharmacovigilance study of the United States Food and Drug Administration’s Adverse Event Reporting System database

in Predictive Toxicology

Houci Yang
Haibin Dai
Xveying Chen
Jiaqi Huang
Fangzhou Miao
Jiani Lv
Jiali Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1555955

327 views

Hypothesis and Theory

Published on 08 Apr 2025

Quantification of signal amplification for receptors: the Kd/EC50 ratio of full agonists as a gain parameter

in Experimental Pharmacology and Drug Discovery

Peter Buchwald

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1541872

203 views

Original Research

Published on 08 Apr 2025

Antibacterial activities of oregano essential oils and their active components

in Pharmacology of Infectious Diseases

Lei Tao
Yan Liang
Zhi Xia
Xinsheng Wang
Xiaodong Wang
Zhe Chao
Jie Guo

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1579283

341 views

Original Research

Published on 08 Apr 2025

Brosimine B and the biphasic dose-response: insights into hormesis and retinal neuroprotection

in Neuropharmacology

Susanne Suely Santos Fonseca
Natacha M. S. Port’s
Gisele Priscila Soares Aguiar
Eliã P. Botelho
Nádia M. G. Couto
Wandson Braamcamp Souza Pinheiro
André Salim Khayat
Elizabeth S. Yamada
Edmar T. Costa
Chubert Bernardo C. Sena

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1558726

224 views

Systematic Review

Published on 08 Apr 2025

Efficacy of Kangfuxin liquid for preventing and treating chemotherapy-induced oral mucositis: a systematic review and meta-analysis of randomized controlled trials

in Ethnopharmacology

Wei Sun
Yang Jian
Xiaolin Feng
Minru Zhao
Yuan Liu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1565345

251 views

Original Research

Published on 08 Apr 2025

Computational drug repurposing in Parkinson’s disease: Omaveloxolone and cyproheptadine as promising therapeutic candidates

in Neuropharmacology

Xin Guo
Jie Wang
Hongyang Fan
Wanying Tao
Zijing Ren
Xingyue Li
Suyu Liu
Peiyang Zhou
Yingzhu Chen

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1539032

637 views

Original Research

Published on 08 Apr 2025

Synergistic chemo-immunotherapy for osteosarcoma via a pH-responsive multi-component nanoparticle system

in Experimental Pharmacology and Drug Discovery

Dapeng Li
Yuanfan Li
Jie Cang
Xianwen Yan
Feipeng Wu
Xuan Sun
Wenchao Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1584245

210 views

Editorial

Published on 08 Apr 2025

Editorial: Neuropharmacological intervention for severe mental illness and suicide prevention

in Neuropharmacology

Ewa Litwa
Stefano Comai
Agnieszka Zelek-Molik

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1599083

156 views

Original Research

Published on 08 Apr 2025

Baicalin reduces sunitinib-induced cardiotoxicity in renal carcinoma PDX model by inhibiting myocardial injury, apoptosis and fibrosis

in Ethnopharmacology

Zefu Yang
Jianping Wan
Xinjin Zhang
Jiaqi Mei
Hua Hao
Sibo Liu
Yun Yi
Meixiu Jiang
Yuanqiao He

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1563194

227 views

Original Research

Published on 08 Apr 2025

In vivo effects of bempedoic acid on microdosed CYP probe drugs

in Drug Metabolism and Transport

Felicitas Stoll
Salvatore Amato
Jürgen Burhenne
Antje Blank

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1544956

253 views

Review

Published on 08 Apr 2025

Digital intelligence technology: new quality productivity for precision traditional Chinese medicine

in Ethnopharmacology

Junqing Zhu
Xiaonan Liu
Peng Gao

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1526187

379 views

Original Research

Accepted on 07 Apr 2025

GluN2B influences the progression of status epilepticus by modulating calcium ion homeostasis through its interaction with CaMKIIα

in Neuropharmacology

Lin Zhang
Youshi Meng
Chaoning Liu
Lei Wei
Yuling Lu
Shouhuan Zheng
Donghua Zou
Yuan Wu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1550879

Original Research

Accepted on 07 Apr 2025

S1PR4-dependent effects of Etrasimod on primary human myeloid immune cell activation

in Inflammation Pharmacology

Fiona Sailer
Megan Palmer
Blerina Aliraj
Jan Heering
Andreas Brockmann
Mohammed A F Elewa
Aissa Röhrig
Ewgenij Proschak
Dariusz T Stepniak
Simeon Ramsey

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1590816

143 views

Original Research

Accepted on 07 Apr 2025

Lateral habenula astroglia modulate the potentiating antidepressant-like effects of bright light stimulation in intractable depression

in Neuropharmacology

Sarah Delcourte
Amel Bouloufa
Renaud Rovera
Elie Brunet
Hiep D Le
April E Williams
Satchidananda Panda
Rihab Azmani
Olivier Raineteau
Ouria Dkhissi-Benyahya

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1592909

121 views

Original Research

Accepted on 07 Apr 2025

Plasticity of ventral tegmental area disturbance during abstinence after repeated amphetamine exposure: restoration by selective activation of group II metabotropic glutamate receptors

in Neuropharmacology

Ornella Valenti
Katarzyna Anna Rekawek
Sophie Wieser
Petra Scholze
Stefan Boehm

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1534101