Frontiers in Pharmacology

Original Research

Accepted on 08 Apr 2025

Acute Liver Injury and Diffuse subcutaneous pneumatosis Following Compound paracetamol and Amantadine hydrochloride tablets Poisoning: A Case Report

in Pharmacoepidemiology

Zhao Zhiwen
Cai Lanlan
Liu Xuefang
Zhicheng Fang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1503449

Original Research

Accepted on 08 Apr 2025

Post-marketing safety concerns with pirfenidone and nintedanib: An analysis of individual case safety reports from the FDA adverse event reporting system (FAERS) database and the Japanese Adverse Drug Event Report (JADER) databases

in Pharmacoepidemiology

Tao Wang
Zhiwei Cui
Yingyong Ou
Siyu Lou
Huayou Chen
Chengyu Zhu
Linmei Zhou
Fan Zou

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1530697

125 views

Original Research

Accepted on 08 Apr 2025

Real-World Pharmacovigilance Analysis of Drug-Related Cataracts Using the FDA Adverse Event Reporting System Database

in Pharmacoepidemiology

Xiang Li
Shu Wen Wang
Zhijie Zhang
Tang Jiafeng
Tao Tao
Zhang yang Luo

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1498191

106 views

Original Research

Accepted on 08 Apr 2025

Mangiferin mitigates dexamethasone-induced insulin resistance in rats: insight on vascular dysfunction and hepatic steatosis

in Experimental Pharmacology and Drug Discovery

Abdullah Q Alsaedi
Manar Nader
Dalia H. El-Kashef
Marwa Abdelmageed

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1572758

Original Research

Published on 08 Apr 2025

Antibiotic-potentiating efficacy of Rosmarinus officinalis L. to combat planktonic cells, biofilms, and efflux pump activities of extensively drug-resistant Acinetobacter baumannii clinical strains

in Pharmacology of Infectious Diseases

Sanaz Khashei
Hossein Fazeli
Fateh Rahimi
Vajihe Karbasizadeh

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1558611

348 views

Review

Published on 08 Apr 2025

Endogenous micropeptides as potential diagnostic biomarkers and therapeutic drugs

in Gastrointestinal and Hepatic Pharmacology

Aixi Zhong
Shuai Li
Jingxuan Zhang
Jingyuan Zhao
Chenhui Yao

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1545575

210 views

Original Research

Published on 08 Apr 2025

Potential inappropriate medications and drug–drug interactions in adverse drug reactions in the elderly: a retrospective study in a pharmacovigilance database

in Drugs Outcomes Research and Policies

Huaqiao Jiang
Yanhua Lin
Weifang Ren
Lina Lu
Xiaofang Tan
Xiaoqun Lv
Ning Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1546012

366 views

Original Research

Published on 08 Apr 2025

Vaccinium myrtillus L. ameliorates diabetic nephropathy via modulating metabolites and gut microbiota in rats

in Renal Pharmacology

Xinxin Cao
Fan Yao
Wenxiu Liu
Yufang Wang
Zhen Zhang
Chongyang Zhang
Zhengqi Dong
Bin Zhang
Ruikun He
Xiaobo Sun

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1541947

304 views

Review

Published on 08 Apr 2025

A novel perspective on bone tumors: advances in organoid research

in Pharmacology of Anti-Cancer Drugs

Zebing Ma
Yibing Liu
Rui Chen
Huayu Fan
Liang Kong
Xiangyang Cao

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1550163

254 views

Original Research

Published on 08 Apr 2025

MDM2 inhibitor induces apoptosis in colon cancer cells through activation of the CHOP-DR5 pathway, independent of p53 phenotype

in Pharmacology of Anti-Cancer Drugs

Manman Lu
Yingli Ren
Sijia Feng
Shenggen Wang
Weiyue Xia
Baoru Gu
Yuhou Shen
Aimin Yue
Na Li
Yongxi Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1508421

334 views

Review

Published on 08 Apr 2025

Anti-inflammatory drugs as potential antimicrobial agents: a review

in Inflammation Pharmacology

Onyedika Emmanuel Okpala
Johana Rondevaldova
Ladislav Kokoska

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1557333

674 views

Original Research

Published on 08 Apr 2025

Identification of novel amides and alkaloids as putative inhibitors of dopamine transporter for schizophrenia using computer-aided virtual screening

in Experimental Pharmacology and Drug Discovery

Iqra Ahmad
Anam Tassawer
Muhammad Umer Khan
Muhammad Shehroz
Umar Nishan
Sheheryar Sheheryar
Hanna Dib
Mohamed A. O. Abdelfattah
Mohibullah Shah

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1509263

570 views

Original Research

Published on 08 Apr 2025

Assessment of competencies of clinical research professionals and proposals to improve clinical research in Portugal

in Drugs Outcomes Research and Policies

Mónica Bogas
Joana Antas
Cátia Magalhães
Mafalda Revige
Liliana Guerra
Cheila Ribeiro
Rita Cunha Eça
Filipa Nunes
Ana Lopes
Luís Costa

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1578955

391 views

Review

Published on 08 Apr 2025

Overview of pharmacodynamical research of traditional Chinese medicine on hyperuricemic nephropathy: from the perspective of dual-regulatory effect on the intestines and kidneys

in Renal Pharmacology

Ting Wang
Li Li
Li Liu
Ruirong Tan
Qinxuan Wu
Xin Zhu
Hua Hua
Ying Dai
Huan Li
Jiuzhou Mao

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1517047

248 views

Systematic Review

Published on 08 Apr 2025

Efficacy of Kangfuxin liquid for preventing and treating chemotherapy-induced oral mucositis: a systematic review and meta-analysis of randomized controlled trials

in Ethnopharmacology

Wei Sun
Yang Jian
Xiaolin Feng
Minru Zhao
Yuan Liu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1565345

250 views

Original Research

Published on 08 Apr 2025

Brosimine B and the biphasic dose-response: insights into hormesis and retinal neuroprotection

in Neuropharmacology

Susanne Suely Santos Fonseca
Natacha M. S. Port’s
Gisele Priscila Soares Aguiar
Eliã P. Botelho
Nádia M. G. Couto
Wandson Braamcamp Souza Pinheiro
André Salim Khayat
Elizabeth S. Yamada
Edmar T. Costa
Chubert Bernardo C. Sena

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1558726

219 views