Frontiers in Pharmacology

Review

Published on 10 Apr 2025

Therapeutic potential and mechanistic insights of astragaloside IV in the treatment of arrhythmia: a comprehensive review

in Ethnopharmacology

Meilian Chen
Binlan Fu
Hao Zhou
Qiaomin Wu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1528208

231 views

Original Research

Published on 10 Apr 2025

Tauroursodeoxycholic acid regulates macrophage/monocyte distribution and improves spinal microenvironment to promote nerve regeneration through inhibiting NF-κB signaling pathway in spinal cord injury

in Neuropharmacology

Yonghui Hou
Yage Zhang
Lin Ma
Dan Luo
Wanshun Wang
Shunmei E.
Chengxi Huang
Yu Hou
Shudong Chen
Jiheng Zhan

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1554945

280 views

Original Research

Published on 10 Apr 2025

The venom of Cyriopagopus schmidti spider contains a natural huwentoxin-IV analogue with unexpected improved analgesic potential

in Pharmacology of Ion Channels and Channelopathies

Aurélie Antunes
Jérôme Montnach
Kuldip Khakh
Ludivine Lopez
Baptiste Thomas
Barbara Ribeiro Oliveira-Mendes
Lucie Jaquillard
Denis Servent
Rémy Béroud
Charles J. Cohen

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1566312

281 views

Review

Published on 10 Apr 2025

Effects of Chinese Medicine on modulating interleukin-17-regulated macrophages in coronary heart disease

in Cardiovascular and Smooth Muscle Pharmacology

Qingqing Liu
Peizhong Liu
Chuangpeng Li
Zhen Zhao
Dawei Wang
Qing Liu
Huawei Yang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1499786

271 views

Original Research

Published on 10 Apr 2025

Pan-cancer analysis identified CD248 as a potential target for multiple tumor types

in Pharmacology of Anti-Cancer Drugs

Li Guo
Yan Liao
Xuyang Zhang
Rongjuan Guo
Zheng Wang
Deqin Yang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1554632

309 views

Original Research

Published on 10 Apr 2025

Carnosine alleviates oxidative stress to prevent cellular senescence by regulating Nrf2/HO-1 pathway: a promising anti-aging strategy for oral mucosa

in Translational Pharmacology

Haoan He
Chao Lv
Yuhong Xie
Wei Li
Zihang Ling
Bin Cheng
Xiaoan Tao

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1559584

267 views

Original Research

Published on 10 Apr 2025

A mechanistic quantitative systems pharmacology model platform for translational efficacy evaluation and checkpoint combination design of bispecific immuno-modulatory antibodies

in Drug Metabolism and Transport

Yiyang Xu
Siyuan Yang
Qi Rao
Yuan Gao
Guanyue Zhou
Dongmei Zhao
Xinsheng Shi
Yi Chai
Chen Zhao

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1571844

399 views

Original Research

Published on 10 Apr 2025

Okra polysaccharide mitigates carrageenan-induced thrombosis in mice by regulating inflammation and oxidative stress

in Ethnopharmacology

Jinping Ni
Xiwen Cao
Xianqing Hu
Shenwen Fu
Meixiu Jiang
Yuqi Ni

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1576108

242 views

Original Research

Published on 10 Apr 2025

NMN reverses D-galactose-induced neurodegeneration and enhances the intestinal barrier of mice by activating the Sirt1 pathway

in Ethnopharmacology

Yuxian Lin
Yajing Wang
Xinxin Yang
Ziwei Ding
Mingye Hu
Xianfeng Huang
Qichun Zhang
Yingcong Yu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1545585

318 views

Original Research

Published on 10 Apr 2025

Impact of clinical pharmacist interventions on medication administration via enteral feeding tubes in a neurology ward: a pre- and post-educational prospective study

in Drugs Outcomes Research and Policies

Yunus Emre Ayhan
Ömer Faruk Özkanlı
Şeyma Gözelizmir
Anmar Al-Taie
Mesut Sancar
Ipek Midi

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1519835

349 views

Review

Published on 10 Apr 2025

Extraction, content determination, component analysis, and pharmacological action of Hedysari flavonoids: a review of research progress

in Ethnopharmacology

Cancan Huang
Haiyan Mao
Wenwen Wan
Chunzhen Ren
Xiujia Ji
Bin Yue
Xiaohua Zhang
Quansheng Wu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1517832

215 views

Review

Accepted on 09 Apr 2025

Targeting Fibroblast Growth Factor (FGF)-21 : A Promising Strategy for Metabolic Dysfunction-Associated Steatotic Liver Disease Treatment

in Gastrointestinal and Hepatic Pharmacology

Xinyue Cui
Quanhao Sun
Haiqiang Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1510322

Original Research

Accepted on 09 Apr 2025

DNA Metabarcoding Unveils Authenticity and Adulteration in Commercial Chinese Polyherbal Preparations: Renshen Jianpi Wan as a Critical Case Study

in Ethnopharmacology

Shilin Zhou
Ting Zhou
Yanmei Zhang
Bingqian Yang
Junmei Niu
Weixian Li
Faming Long
Zhenwen Liu
Jing Zhou
yiyi Weitu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1584065

130 views

Original Research

Accepted on 09 Apr 2025

Genetic Polymorphisms in SLC5A2 are Associated with Clinical Outcomes and Dapagliflozin Response in Heart Failure Patients

in Pharmacogenetics and Pharmacogenomics

Ahmed Essam Abou Warda
Rylie M. Flohr
Rania M. Sarhan
Mohamed Nabil Salem
Heba F. Salem
Ayman N. Moharram
Abdullah S Alanazi
Christelle Lteif
Brian E. Gawronski
Leanne Dumeny

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1539870

141 views

Review

Accepted on 09 Apr 2025

Studies on the Mechanism of Ototoxic Action of Cisplatin and the Antagonistic Effect of Polyphenolic Compounds

in Pharmacology of Anti-Cancer Drugs

Yuhua Chi
Shengyu Han
Jinjun Sun
Wenpeng Li
Jihong Li
Haoming Yu
Shuai Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1586243

Original Research

Accepted on 09 Apr 2025

Synthesis, Anti-cancer Activity, and Mechanistic Insights of 2H-benzo[b][1,4]oxazin-3(4H)-one Linked 1,2,3-Triazoles in Human Cancer Cell Lines

in Pharmacology of Anti-Cancer Drugs

Qing-Ying Liu
Xixi Hou
Mingyue Tian
Baoyu He
Jingjing Guo
Yajie Guo
Jianxue Yang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1565657