Policy Brief

Published on 14 Nov 2024

Identifying and overcoming challenges in the EMA’s qualification of novel methodologies: a two-year review

in Drugs Outcomes Research and Policies

Ana Drmić
Riccardo Saccà
Thorsten Vetter
Falk Ehmann

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1470908

144 views

Original Research

Published on 14 Nov 2024

Novel genomic variants influencing methotrexate delayed clearance in pediatric patients with acute lymphoblastic leukemia

in Pharmacogenetics and Pharmacogenomics

Jung Yoon Choi
Hoshik Kwon
Hyery Kim
Kyung Taek Hong
Youngeun Ma
Kyung-Nam Koh
Sunmin Yun
Keon Hee Yoo
Sang Hoon Song
Ho Joon Im

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1480657

167 views

Original Research

Published on 14 Nov 2024

Effectiveness analysis of a pharmacist-led intervention for orthopedic perioperative use of antibiotics: a retrospective cohort study

in Drugs Outcomes Research and Policies

Danwei Wu
Yingxu Li
Jiancun Zhen
Yong Wu
Shuang Ren
Yuan Zhao
Ning Sun
Xuanzi Lin
Liangpeng Lai
Wei Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1365370

134 views

Original Research

Accepted on 13 Nov 2024

Integration of pharmacogenetic data in Epic Genomic Module drives best practice alerts

in Pharmacogenetics and Pharmacogenomics

Kimberly Newsom
Bradley Hall
Katherine Martinez
Scott Nelson
Petr Starostik
Khoa Nguyen

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1458095

140 views

Original Research

Accepted on 13 Nov 2024

Protective effect of Haoqin Qingdan decoction on pulmonary and intestinal injury in mice with influenza virus pneumonia

in Ethnopharmacology

Xi Lin
Jian Lin
Lichun Ji
Jiaona Zhang
Yezi Zhang
Junbin Hong
Geng Li
Xingdong Lin

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1449322

Original Research

Accepted on 13 Nov 2024

Investigation of the effects of Periplaneta americana (L.) extract on ischemic stroke based on combined multi-omics of gut microbiota

in Experimental Pharmacology and Drug Discovery

Xin Yang
Canhui Hong
Tangfei Guan
ChengGui Zhang
Pei Yun Xiao
Yongshou Yang
Huai Xiao
Zhengchun He

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1429960

Original Research

Accepted on 13 Nov 2024

A functional unbalance of TRPM8 and Kv1 channels underlies orofacial cold allodynia induced by peripheral nerve damage

in Neuropharmacology

Ricardo Piña
Gonzalo Ugarte
Camilo Guevara
Richard Pino
Katherine Valdebenito
Sofía Romero
Ana Gómez del Campo
Víctor Hugo Cornejo
María Pertusa
Rodolfo Madrid

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1484387

Original Research

Accepted on 13 Nov 2024

Network pharmacology, experimental validation and pharmacokinetics integrated strategy to reveal pharmacological mechanism of Goutengsan on methamphetamine dependence

in Translational Pharmacology

Han-cheng Li
Jie-Yu Li
Xing-Chen Wang
Ming Zeng
Yang-Kai Wu
Yi-Ling Chen
Cai-Hua Kong
Ke-Lin Chen
Jie-Ru Wu
Zhi-Xian Mo

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1480562

Review

Accepted on 13 Nov 2024

Pharmacology and Mechanisms of Apigenin in Preventing Osteoporosis

in Integrative and Regenerative Pharmacology

Lin Sun
Yincang Wang
Jiazhe Du
Xilin Xu
Xiaofeng Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1486646

Original Research

Accepted on 13 Nov 2024

Dexmedetomidine regulates the anti-oxidation and autophagy of adipose-derived stromal cells under H2O2-induced oxidative stress through Nrf2/p62 pathway and improves the retention rate of autologous fat transplantation Authors and affiliations

in Experimental Pharmacology and Drug Discovery

Zihao Li
Qing Wei
Fangfang Yang
Chen Ke
Tian Li
Yijun Li
Liqun Li
Zhongming Cai

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1453938

Original Research

Accepted on 13 Nov 2024

Tenecteplase: Biochemical and clot lysis activity comparisons

in Cardiovascular and Smooth Muscle Pharmacology

Jan Bechmann
Ira Schmid
Simone Brand
Felix Miller
Chengzhi Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1498116

Systematic Review

Accepted on 13 Nov 2024

Network meta-analysis of integrated traditional Chinese and Western medicine in the treatment of Sjogren's syndrome

in Ethnopharmacology

Xie Li Ma
Liu Zixia
Tian Chang
Chuanhui Yao
Yuchen Yang
Biyue Shang
Jiameng Liu
Congmin Xia
Gong Xun
Quan Jiang

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1455969

Original Research

Published on 13 Nov 2024

Glucocorticoids influence on rat hematological parameters and catalase activity

in Experimental Pharmacology and Drug Discovery

Safija Herenda
Ivana Carev
Denis Haskovic
Sabina Prevljak
Sara Causevic
Edhem Haskovic

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1367350

125 views

Original Research

Published on 13 Nov 2024

Mechanism of Apigenin against breast cancer stem cells: network pharmacology and experimental validation

in Pharmacology of Anti-Cancer Drugs

Mengdie Ou
Zhicheng Deng
Yonghui Shi
Jianxiong He
Zicong Ye
Ming Guo
Guohua Cheng
Junyan Wu
Li Lv

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1496664

198 views

Original Research

Published on 13 Nov 2024

First transcriptome analysis of the venom glands of the scorpion Hottentotta zagrosensis (Scorpions: Buthidae) with focus on venom lipolysis activating peptides

in Integrative and Regenerative Pharmacology

Fatemeh Salabi
Hedieh Jafari
Masoud Mahdavinia
Reza Azadnasab
Saeedeh Shariati
Mahsa Lari Baghal
Majid Tebianian
Masoumeh Baradaran

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1464648

440 views

Review

Published on 13 Nov 2024

In-depth analysis of lupeol: delving into the diverse pharmacological profile

in Experimental Pharmacology and Drug Discovery

Aminah Dalimunthe
Mega Carensia Gunawan
Zahirah Dhiya Utari
Muhammad Riza Dinata
Princella Halim
Nathasya Estherina S. Pakpahan
Alex Insandus Sitohang
M. Andriansyah Sukarno
Yuandani
Yahdiana Harahap

Frontiers in Pharmacology

doi 10.3389/fphar.2024.1461478

534 views

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Articles

Identifying and overcoming challenges in the EMA’s qualification of novel methodologies: a two-year review

Novel genomic variants influencing methotrexate delayed clearance in pediatric patients with acute lymphoblastic leukemia

Effectiveness analysis of a pharmacist-led intervention for orthopedic perioperative use of antibiotics: a retrospective cohort study

Integration of pharmacogenetic data in Epic Genomic Module drives best practice alerts

Protective effect of Haoqin Qingdan decoction on pulmonary and intestinal injury in mice with influenza virus pneumonia

Investigation of the effects of Periplaneta americana (L.) extract on ischemic stroke based on combined multi-omics of gut microbiota

A functional unbalance of TRPM8 and Kv1 channels underlies orofacial cold allodynia induced by peripheral nerve damage

Network pharmacology, experimental validation and pharmacokinetics integrated strategy to reveal pharmacological mechanism of Goutengsan on methamphetamine dependence

Pharmacology and Mechanisms of Apigenin in Preventing Osteoporosis

Dexmedetomidine regulates the anti-oxidation and autophagy of adipose-derived stromal cells under H2O2-induced oxidative stress through Nrf2/p62 pathway and improves the retention rate of autologous fat transplantation Authors and affiliations

Tenecteplase: Biochemical and clot lysis activity comparisons

Network meta-analysis of integrated traditional Chinese and Western medicine in the treatment of Sjogren's syndrome

Glucocorticoids influence on rat hematological parameters and catalase activity

Mechanism of Apigenin against breast cancer stem cells: network pharmacology and experimental validation

First transcriptome analysis of the venom glands of the scorpion Hottentotta zagrosensis (Scorpions: Buthidae) with focus on venom lipolysis activating peptides

In-depth analysis of lupeol: delving into the diverse pharmacological profile