Frontiers in Pharmacology

Editorial

Accepted on 11 Apr 2025

Advanced Therapeutic Strategies and Safety Profiles in Heart Failure with Reduced Ejection Fraction: Contextualizing Recent Findings

in Cardiovascular and Smooth Muscle Pharmacology

Maria del Carmen Asensio Lopez
Paolo Severino
Antonio Lax

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1607362

176 views

Original Research

Accepted on 11 Apr 2025

Prediction of pharmacokinetic/pharmacodynamic properties of aldosterone synthase inhibitors at drug discovery stage using an artificial intelligence-physiologically based pharmacokinetic model

in Drug Metabolism and Transport

Mengjun Zhang
Keheng Wu
Sihui Long
Xiong Jin
Bo Liu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1578117

Original Research

Accepted on 11 Apr 2025

Loss of expression and function of Gβγ by GNB1 Encephalopathy-associated L95P mutation of Gβ 1 subunit

in Neuropharmacology

Haritha Polagari Reddy
Tal Keren-Raifman
Galit Tabak
Nathan Dascal
Daniel Yakubovich

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1592012

102 views

Perspective

Accepted on 11 Apr 2025

How to protect Chinese medicine prescriptions more effectively？

in Ethnopharmacology

Xiaochang Liu
Gaoyuan Zhai

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1545986

Systematic Review

Accepted on 11 Apr 2025

Comparative Effectiveness of Semaglutide versus Liraglutide, Dulaglutide or Tirzepatide: a systematic review and meta-analysis

in Drugs Outcomes Research and Policies

Parisa Alsadat Dadkhah
Mohammad Amin Karimi
Farzad Sheikhzadeh
Mohammad Sadra Gholami Chahkand
Shayan Yaghoubi
Fatemeh Esmaeilpour Moallem
Mitra Sadat Deyhimi
Melika Arab Bafrani
Mehregan Shahrokhi

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1438318

162 views

Review

Accepted on 11 Apr 2025

Efficacy, Safety, and Tolerability of Soticlestat (TAK-935) as Adjunctive Therapy in Pediatric Patients with Dravet syndrome and Lennox-Gastaut syndrome: A Meta-analysis of 3 Randomized Controlled Trials

in Neuropharmacology

Zhang Lanlan
Jiang Nana
Wang Chengzhong

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1586098

181 views

Review

Accepted on 11 Apr 2025

-Nitro-2-Phenylethane: a promising phytoconstituent to modulate neuroinflammation and oxidative stress with repercussions on neurological and psychiatric disorders

in Neuropharmacology

Lucas Pantoja
Emily Christie Fonseca
Fábio José Coelho Souza-Junior
Brenda Costa Conceição
Sarah Viana Farias
JOYCE KELLY R. DA SILVA
Jose Guilherme Soares Maia
Daniele Luz Moraes
Pedro Iuri Castro Silva
Rui Daniel Prediger

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1552295

Original Research

Accepted on 11 Apr 2025

Exploring the Diagnostic Potential of IL1R1 in Depression and Its Association with Lipid Metabolism

in Neuropharmacology

Yao Gao
Xiao-Na Song
Nan Zhang
Huang-Hu Liu
Jian-Zhen Hu
Xin-Zhe Du
Guo-Hua Song
Sha Liu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1519287

Original Research

Accepted on 11 Apr 2025

Efficacy of Sodium New Houttuyfonate Against Aspergillus flavus: Insights from In Vitro and In Vivo Models of Invasive Pulmonary Aspergillosis

in Ethnopharmacology

Yilin Bao
Dingxian Feng
Jinping Zhang
Xiaoyan Hu
Xinyou Yang
Yingyu Mao
Zhangyong Song

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1577561

Review

Accepted on 11 Apr 2025

Research advances in traditional Chinese Medicine formulae and active components targeting lipid metabolism for hepatocellular carcinoma therapy

in Ethnopharmacology

Yang Liu
Jie Yang
Fenghua Yu
Li Li
Ning Zhao
Cheng LU
Aiping Lyu
Xiaojuan He

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1528671

Correction

Accepted on 11 Apr 2025

Synthesis, Characterization, and Computational Evaluation of Some Synthesized Xanthone Derivatives: Focus on Kinase Target Network and Biomedical Properties

in Pharmacology of Anti-Cancer Drugs

Wisam Taher Muslim
Layth Mohammed
Munaf M. Naji
ISAAC KARIMI
Matheel D. Al-Sabti
Majid Jabir
Mazin A. A. Najm
Helgi B. Schiöth

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1583894

Original Research

Accepted on 11 Apr 2025

Regulating mitochondrial oxidative phosphorylation and MAPK signaling: wedelolactone as a novel therapeutic for radiation-induced thrombocytopenia

in Ethnopharmacology

Zhichao Li
Qinyao Li
Shuang Wu
Xinyue Mei
Xiao Qi
Sheng Liu
Gan Qiao
Hongping Shen
Jiesi Luo
Jing Zeng

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1508215

Original Research

Accepted on 11 Apr 2025

Saikosaponin A Induces Cellular Senescence in Triple-negative Breast Cancer by Inhibiting the PI3K/Akt Signalling Pathway

in Ethnopharmacology

Yingchao Wu
Chen Liushan
Dajin Pi
Jiaqi Cui
Yuqi Liang
Peng Wu
Mingzi Ouyang
Qian Zuo

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1532579

148 views

Original Research

Accepted on 11 Apr 2025

Rosa roxburghii Tratt juice Ameliorates Metabolic Disorder in Arsenicosis Patients Based on the Analysis of Untargeted Plasma Metabolomics

in Ethnopharmacology

Luming Yang
Kai Zhu
Wenjuan Wang
Baofei Sun
Peng Luo
Aihua Zhang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1488113

Brief Research Report

Accepted on 11 Apr 2025

Regulatory Challenges of Digital Health: The case of mental health applications and personal data in South Africa

in Drugs Outcomes Research and Policies

Marietjie Wilhelmina Maria Botes

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1498600

113 views

Original Research

Accepted on 11 Apr 2025

Bioactive Natural Alkaloid 6-Methoxydihydrosanguinarine Exerts Anti-Tumor Effects in Hepatocellular Carcinoma Cells via Ferroptosis

in Pharmacology of Anti-Cancer Drugs

Linfen Han
Chengchang Gao
Xiaorui Jin
Yingping Li
Liangjie Chen
Donglin Li
Qinqin Deng
Xueli Bian

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1500461