Frontiers in Pharmacology

Original Research

Published on 04 Apr 2025

Evaluating the anti-neuropathic effects of the thymol-loaded nanofibrous scaffold in a rat model of spinal cord injury

in Ethnopharmacology

Roshanak Amirian
Pardis Mohammadi Pour
Hassan Maleki
Sajad Fakhri
Sedigheh Asgary
Mohammad Hossein Farzaei
Javier Echeverría

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1507397

136 views

Original Research

Published on 04 Apr 2025

The ultrafine powder of atractylodis macrocephalae rhizoma improves immune function in naturally aging rats by regulating the PI3K/Akt/NF-κB signaling pathway

in Translational Pharmacology

Wang Yu
Su Jie
Gao Su
Niu Zhuangwei
Zhou Yiqing
Chen Suhong
Lv Guiyuan

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1550357

Systematic Review

Published on 04 Apr 2025

The efficacy of different doses of citicoline in improving the prognosis of patients with acute ischemic stroke based on network meta-analysis

in Translational Pharmacology

Xu Zhao
Xianhao Huo
Yizhen Meng
Ran Zhao
Xiaozhuo Liu
Jiancheng Chen
Zhiqi Mao
Mei Li

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1529647

139 views

Original Research

Published on 04 Apr 2025

MicroRNA-665 and its potential role in drug response and survival outcomes in multiple myeloma: a preliminary study

in Pharmacology of Anti-Cancer Drugs

Rui Bergantim
Sara Peixoto da Silva
Vanessa Pinto
Joana M. Pereira
Diana Sousa
Fernanda Trigo
Rune Matthiesen
José E. Guimarães
M. Helena Vasconcelos

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1465814

147 views

Case Report

Published on 04 Apr 2025

Case Report: A case of Felty’s syndrome with initial presentation of pleural effusion and subsequent Escherichia coli pyothorax

in Respiratory Pharmacology

Haifeng Yang
Weiqin Wang
Yongfeng Liu
Yibo Yang
Yiliang Su

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1529621

Original Research

Published on 04 Apr 2025

Antiviral activity of eicosapentaenoic acid against zika virus and other enveloped viruses

in Pharmacology of Infectious Diseases

Yifei Feng
Shuqi Qiu
Shuting Zou
Ru Li
Hongyu Chen
Kaitian Chen
Junbo Ma
Jinyu Liu
Xiaoyun Lai
Shuwen Liu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1564504

130 views

Original Research

Published on 04 Apr 2025

Development and validation of hierarchical signature for precision individualized therapy based on the landscape associated with necroptosis in clear cell renal cell carcinoma

in Pharmacology of Anti-Cancer Drugs

Gao-Sheng Yao
Jun-Shang Dai
Liang-Min Fu
Juan Lin
Zhi-Ping Tan
Lei Dai
Wei Chen
Jun-Hang Luo
Jin-Huan Wei

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1470145

Original Research

Published on 04 Apr 2025

Incidence and determinants of excessive weight gain in people living with HIV initiating tenofovir, lamivudine, and dolutegravir-based therapy: a multicenter retrospective study in northwest Ethiopia

in Pharmacoepidemiology

Gashaw Sisay Chanie
Wagaye Atalay
Tirsit Ketsela Zeleke
Zemenu Wube Bayleyegn
Yonas Sisay Aragie
Gizachew Kassahun Bizuneh
Mihret Melese
Rahel Belete Abebe

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1394458

Original Research

Published on 04 Apr 2025

Eculizumab is efficacious and safe in pediatric patients with various forms of hemolytic uremic syndrome: a retrospective clinical experience of a tertiary center

in Renal Pharmacology

Naama Lax
Miriam Davidovits
Gabriel Chodick
Yael Bernfeld
Orit Peled

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1535407

100 views

Original Research

Published on 04 Apr 2025

Bone loss in young adults with HIV following antiretroviral therapy containing tenofovir disoproxil fumarate regimen using machine learning

in Pharmacology of Infectious Diseases

Ling Chen
Jia Tang
Leidan Zhang
Liyuan Zheng
Fada Wang
Fuping Guo
Yang Han
Xiaojing Song
Wei Lv
Wei Cao

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1516013

Original Research

Published on 04 Apr 2025

MiR-3613-5p targets AQP4 to promote the progression of chronic atrophic gastritis to gastric cancer

in Gastrointestinal and Hepatic Pharmacology

Jian Bi
Yufen Wang
Yingde Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1523689

Original Research

Published on 04 Apr 2025

Landscape analysis of m6A modification regulators reveals LRPPRC as a key modulator in tubule cells for DKD: a multi-omics study

in Renal Pharmacology

Li Jiang
Hongda Yu
Jie Jian
Xulin Sai
Yudian Wang
Yufei Zhang
Xiai Wu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1506896

Original Research

Published on 04 Apr 2025

Suppressed intestinal secondary bile acids in moxifloxacin-induced hyperglycemia: studies in normal and diabetic GK rats

in Gastrointestinal and Hepatic Pharmacology

Yewen Sun
Yuchen Qu
Zhuan Yang
Bo Lv
Guanjun Wang
Kai Fan
Yuyuan Wang
Jie Pan
Ziyan Du
Yunli Yu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1569856

Review

Published on 04 Apr 2025

The emerging role of vascular endothelial cell-mediated angiogenesis in the imbalance of RA synovial microenvironment and its clinical relevance

in Inflammation Pharmacology

Xingxing Huo
Yanhui Peng
Hui Li
Chen Li
Faxue Liao
Chenggui Miao
Yurong Huang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1481089

Original Research

Published on 04 Apr 2025

Composite outcome of oral azvudine vs. nirmatrelvir-ritonavir in COVID-19 patients: a retrospective cohort study

in Pharmacology of Infectious Diseases

Jingxia Chen
Zhengyue Liu
Ruolin Liu
Chengxin Su
Yunyun Yang
Zhuo Wang

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1546787

Original Research

Published on 04 Apr 2025

Multi-tissue metabolomics analysis reveals susceptible factors for chemotherapy-induced hepatotoxicity in colorectal cancer patients

in Drug Metabolism and Transport

Huilin Xu
Mingming Li
Houshan Yao
Guoliang Chen
Jiani Chen
Xinyun Hou
Hong Yang
Chenghang Yu
Zeshuai Lin
Jiawei Zhu

Frontiers in Pharmacology

doi 10.3389/fphar.2025.1517446