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Original Research

Published on 21 Mar 2024

Phase 1, first-in-human study of TYRP1-TCB (RO7293583), a novel TYRP1-targeting CD3 T-cell engager, in metastatic melanoma: active drug monitoring to assess the impact of immune response on drug exposure

in Pharmacology of Anti-Cancer Drugs

  • Anna Spreafico
  • Eva Muñoz Couselo
  • Anja Irmisch
  • Juliana Bessa
  • George Au-Yeung
  • Oliver Bechter
  • Inge Marie Svane
  • Miguel F. Sanmamed
  • Valentina Gambardella
  • Meredith McKean
Frontiers in Oncology
doi 10.3389/fonc.2024.1346502
  • 5,717 views
  • 3 citations